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The clinical effects and serum concentrations of sulpiride ib positive and negative symptom schizophrenics

Ahn YY, Hahn KH

  • KMID: 1692544
  • J Korean Neuropsychiatr Assoc.
  • 1993 Nov;32(6):983-990.
No abstract available.
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Sulpiride in Meige's Syndrome: Possible Role of Glutamate

Lee SA, Kim JS, Ahn JH, Choi KG

Sulpiride, a selective antagonist for adenylate cyclase-independent dopamine receptors, was administrated to 25 patients with blepharospasm and oromandibular dystonia(Meige's syndrome). Of the 25, 7 patients (28%) exhibited marked and lasting...
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Influence of Diazepam, Cimetidine and Sulpiride on the Level of Hepatic Microsomal Cytochrome P-450 in Rats

Kim BH, Ham YA, Hong YS, Sung NE

Cytochrome P-450 is a terminal oxidase of the hepatic microsomal monooxygenase system associated with the oxidative biotransformation of a varity of lipophilic endogenous and exogenous compounds, and generally is assayed...
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Clinical Experience of Clozapine Discontinuation: Comparison between Sulpiride and Thioridazine Switch Group

Lee HS, Koo MS, Cho HS, Park IH, Kim CH

  • KMID: 1985327
  • Korean J Psychopharmacol.
  • 2002 Jun;13(2):104-112.
OBJECTIVE: Several reports have found that withdrawal symptoms of clozapine are more severe and common than that of the typical antipsychotics. The objective of this study was to report the...
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Response of I(Kr) and hERG Currents to the Antipsychotics Tiapride and Sulpiride

Jo SH, Lee SY

The human ether-a-go-go-related gene (hERG) channel is important for repolarization in human myocardium and is a common target for drugs that prolong the QT interval. We studied the effects of...
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A Case of Atypical Neuroleptic Malignant Syndrome following Rebound Psychosis during Withdrawal of Clozapine

Kim CH, Lee HS

  • KMID: 1985346
  • Korean J Psychopharmacol.
  • 1998 Oct;9(2):188-192.
We experienced one case of neuroleptic malignant syndrome (NMS) caused by a discontinuation of clozapine and rapid initiation of sulpiride and haloperidol injection. The patient was a 37-year-old man with...
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Dopamine Modulates Corticostriatal Synaptic Transmission through Both D1 and D2 Receptor Subtypes in Rat Brain

Lee HH, Choi SJ, Kim KJ, Cho HS, Kim SY, Sung KW

  • KMID: 1600108
  • Korean J Physiol Pharmacol.
  • 2005 Oct;9(5):263-268.
Striatum has important roles in motor control, habitual learning and memory. It receives glutamatergic inputs from neocortex and thalamus, and dopaminergic inputs from substantia nigra. We examined effects of dopamine...
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Differential Effects of Antipsychotic Drugs on Dopamine D1 and D2 Receptor mRNAs in the Rat Brain

Kim MO, Kim YS, Park CH, Yang YA, Kang SS, Cho GJ, Roh GS, Choi WS

  • KMID: 1564378
  • Korean J Anat.
  • 2005 Aug;38(4):363-370.
The principal aim of this study was to determine the effects of antipsychotics (haloperidol, sulpiride, and clozapine) on regulating dopamine (DA) D1 and D2 receptor mRNA levels in the rat...
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The Role of Spinal Dopaminergic Transmission in the Analgesic Effect of Nefopam on Rat Inflammatory Pain

Kim DY, Chae JW, Lim CH, Heo BH, Park KS, Lee HG, Choi JI, Yoon MH, Kim WM

BACKGROUND: Nefopam has been known as an inhibitor of the reuptake of monoamines, and the noradrenergic and/or serotonergic system has been focused on as a mechanism of its analgesic action....
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A Case of Very-late-onset Schizophrenia-like Psychosis

Son JH, Kee BS

  • KMID: 2171266
  • Clin Psychopharmacol Neurosci.
  • 2011 Aug;9(2):91-93.
This paper presents the case of a 67-year-old woman who visited the Psychiatry Department complaining of persecutory ideas and auditory hallucinations after a buccal cancer operation. On neuropsychological testing, she...
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The effect of typical and atypical antipsychotic drugs on the mRNA expression of rat mesencephalic D2 receptor

Shon YH, Kim JS

  • KMID: 1536883
  • J Korean Neurol Assoc.
  • 1997 Oct;15(5):1022-1041.
Recently various types of dopamine receptors have been proved to exist in human central nervous system. And the understanding of the of specific function is expected to improve therapeutic effect...
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Recent Trends of Antipsychotics Polypharmacy in Schizophrenia

Chang JG, Roh D, Kim CH

  • KMID: 2287447
  • Korean J Psychopharmacol.
  • 2013 Oct;24(4):137-146.
Antipsychotics polypharmacy is a common practice in clinical settings despite the opposition of most guidelines for treatment of schizophrenia. This article reviews the evidence of antipsychotics polypharmacy and summarizes advantages...
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Dopaminergic inhibition of dorsal horn cell activity in the cat

Kim KC, Shin HK, Kim KS

  • KMID: 2071824
  • Korean J Physiol Pharmacol.
  • 1998 Dec;2(6):661-670.
Dopamine has been generally known to exert antinociceptive action in behavioral pain test, such as tail flick and hot plate test, but there appears to be a great variance in the reports...
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Pharmacological Treatments for Tinnitus

Park SY

Pharmacotherapy has been constantly chosen by the clinician among the available treatment options for tinnitus. Medications that have been prescribed off-label to treat tinnitus can be grouped into several categories:...
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Effects of Central Dopaminergic Receptor-Activation on the Cardiovascular System

Kim SM, Park YK, Lee SS, Ko CM

  • KMID: 1957399
  • J Korean Neurol Assoc.
  • 1992 Sep;10(3):308-315.
The central dopaminergic receptor is believed to suppress the cardiovascular system So it may be involved in the blood pressure regulation But, it's action is still controversial. Furthermore, the mechanisms...
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A Case of Amisulpride Induced Tardive Blepharospasm in Schizophrenia

Park WR, Kong SW, Yu JC, Lee CH, Choi KS

  • KMID: 2287500
  • Korean J Psychopharmacol.
  • 2012 Jul;23(3):122-125.
Tardive blepharospam is characterized by repetitive, forceful, and sustained involuntary contractions of the orbicularis oculi. We report here one case of neuroleptic-induced tardive blepharospasm that developed during high-dose amisulpride treatment...
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Exposure to Extremely Low Frequency Magnetic Fields Induces Fos-Related Antigen-Immunoreactivity Via Activation of Dopaminergic D1 Receptor

Shin EJ, Nguyen XK, Nguyen TT, Pham DT, Kim HC

We previously demonstrated that repeated exposure to extremely low frequency magnetic fields (ELF-MF) increases locomotor activity via stimulation of dopaminergic D1 receptor (J. Pharmacol. Sci., 2007;105:367-371). Since it has been...
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Gap Junction Contributions to the Goldfish Electroretinogram at the Photopic Illumination Level

Kim DY, Jung CS

Understanding how the b-wave of the electroretinogram (ERG) is generated by full-field light stimulation is still a challenge in visual neuroscience. To understand more about the origin of the b-wave,...
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Effects of levosulpiride in patients with functional dyspepsia accompanied by delayed gastric emptying

Song CW, Chun HJ, Kim CD, Ryu HS, Choe JG, Hyun JH

  • KMID: 759060
  • Korean J Intern Med.
  • 1998 Feb;13(1):15-21.
OBJECTIVES: Levosulpiride is the levo-enantiomer of sulpiride, a well-known antiemetic, antidyspeptic and antipsychotic drug. This study was undertaken to investigate the effects of levosulpiride on dyspeptic symptoms and gastric motor ...
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Antipsychotic-Induced Sexual Dysfunction and Its Management

Park YW, Kim Y, Lee JH

  • KMID: 2320871
  • World J Mens Health.
  • 2012 Dec;30(3):153-159.
Sexual dysfunction is a common condition in patients taking antipsychotics, and is the most bothersome symptom and adverse drug effect, resulting in a negative effect on treatment compliance. It is...
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