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Transition of Marker Enzymes of Rat Hepatocyte Organelles in Culture

Song IH, Kim JY, Sung EK, Lee YC

To investigate recovery, growth, and activity of hepatocyte in primary culture after cell separation, the authors followed up the marker enzyme activities of golgi complex, mitochondria and biologic membrane. Thiamine pyrophosphatase,...
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Pathologic Findings of Mitochondrial Myopathy

Kim L, Kim TS

  • KMID: 2037275
  • Korean J Pathol.
  • 2000 Jan;34(1):77-84.
Mitochondrial myopathy (MM) has been applied to muscle disease in which mitochondria have abnormal structure, function or both. To characterize the pathologic findings of MM, we examined the ultrastructural and...
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In Vitro Study On The Cytotoxicity Of The Differently Sterilized Demineralized Bone Powder

Woo KS, Yim CJ, Kim SW, Kim JY

  • KMID: 1960896
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 1997 Aug;19(3):287-299.
Procurement, cutting, cleansing. freezing. freeze-drying, and demineralization of the allogeneic bone must be under the germ-free stable condition without bacterial and/or viral contamination. Even though the bone is procured under...
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A Histological(Histochemical) Study of the Structural and Functiona1 Unit of the Liver of the Mouse II. On the Distribution of Succinic Dehydrogenase

Pak SY

The hepatic structural and functional unit of the mouse was demonstrated by the relative enzymatic activity of succinic dehydrogenase in the hepatic parenchyma, empIoying the method for succinic dehydrogenase of...
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Update on Gastrointestinal Stromal Tumors for Radiologists

Tirumani S, Baheti AD, Tirumani H, O'Neill A, Jagannathan JP

The management of gastrointestinal stromal tumors (GISTs) has evolved significantly in the last two decades due to better understanding of their biologic behavior as well as development of molecular targeted...
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Enzyme Histochemical Study for the Estimation of the Lapse of Time in Brain Injury

Kim CH, Shin H, Cho KH, Kim HK

  • KMID: 2068160
  • J Korean Neurosurg Soc.
  • 1984 Mar;13(1):61-69.
This experiment was designed for the evaluation of the usefulness of enzyme histochemistry in the determination of the lapse of time in brain wound, and also for the establishment of...
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Mitochondrial myopathies caused by prolonged use of telbivudine

Lee JM, Shin JH, Park YE, Kim DS

BACKGROUND: Telbivudine is a nucleoside analogue used for the treatment of chronic hepatitis B, but it often develops mitochondrial toxicity leading to symptomatic myopathy. In this study, three patients with...
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Mitochondrial Dysfunction and Apoptosis Related Gene Expression in A beta(25-35)-Treated Human Neuroblastoma Cell Line, SK-N-SH

Choi YS, Kim SH

  • KMID: 2338986
  • J Korean Geriatr Soc.
  • 2009 Sep;13(3):142-151.
BACKGROUND: Mitochondrial dysfunction plays an important role in Abeta-induced neuronal toxicity in Alzheimer's disease (AD). We measured the membrane potentials of mitochondria (delta psim) and assessed the genetic expressions of...
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Measurements of Malonate Concentration in Rabbit with Experimental SAH

Kim JJ, Ha YS, Paik SR, Chang CS, Kim YS

  • KMID: 1955077
  • J Korean Neurosurg Soc.
  • 1995 Oct;24(10):1121-1129.
Malonate is regarded as a reversible competitive inhibitor of succinate dehydrogenase and malate transport in the Krebs cycle and showed neurotoxicity by persistent NMDA receptor activation due to inhibition of...
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Expression of Apurinic/apyrimidinic Endonuclease and Neuronal Apoptosis in the Striatum after Treatment of 3-Nitropropionic Acid in Mice

Cho KJ, Lee DJ, Lee BI, Kim GW

  • KMID: 2185341
  • J Korean Neurol Assoc.
  • 2005 Aug;23(4):510-518.
BACKGROUND: 3-Nitroporpionic acid (3-NP) is an irreVersible inhibitor of succinate dehydrogenase in mitochondria and can induce apoptosis-like cell death in the striatum. It has been reported that oxidative stress plays...
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Clinical Manifestations of Mitochondrial Diseases

Kwon SU, Lee KH, Kim DE, Hwang YS, Chun YK, Chi JG, Lee KW

  • KMID: 2066017
  • J Korean Neurol Assoc.
  • 1995 Dec;13(4):941-953.
According to the recently published reports about mitochondrial diseasbl the clinical manifestations are more various than expected. There have been no clinical studies covering whole spectrum of mitochond7iral disease except...
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ACN9 Regulates the Inflammatory Responses in Human Bronchial Epithelial Cells

Jeong JH, Kim J, Kim J, Heo HR, Jeong JS, Ryu YJ, Hong Y, Han SS, Hong SH, Lee SJ, Kim WJ

BACKGROUND: Airway epithelial cells are the first line of defense, against pathogens and environmental pollutants, in the lungs. Cellular stress by cadmium (Cd), resulting in airway inflammation, is assumed to...
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Enzyme histochemical study of germanium dioxide-induced mitochondrial myopathy in rats

Yim SY, Lee IY, Kim TS

The purpose of this study were 1) to determine the earliest pathological changes of germanium dioxide (GeO2)-induced myopathy; 2) to determine the pathomechanism of GeO2-induced myopathy; and 3)...
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Application of Hemin-Agarose Affinity Chromatography to Enrich Proteome Components of Helicobacter pylori Strain 26695

Kang HL, Baik SC

  • KMID: 1574111
  • J Bacteriol Virol.
  • 2005 Jun;35(2):77-85.
The whole cell extract of Helicobacter pylori strain 26695 was treated with the hemin-agarose resin and the bound fraction was analyzed by 2-Dimensional electrophoresis. The 2-D-PAGE-displayed spots were eluted and...
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Gallbladder Paraganglioma Associated with SDHD Mutation: a Potential Pitfall on ¹⁸F-FDOPA PET Imaging

Sater ZA, Jha A, Mandl A, Mangelen S, Carrasquillo JA, Ling A, Gonzales M, Lopes Abath Neto O, Miettinen , Adams KT, Nockel P, El Lakis M, Pacak K

A 36-year-old male patient initially presented with hypertension, tinnitus, bilateral carotid masses, a right jugular foramen, and a periaortic arch mass with an elevated plasma dopamine level but an otherwise...
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Devrease of Mitochondrial DNA Content in Non-Insulin Dependent Diabetic Rats

Song JH, Yim SH, Han BG, Lee HK, Kim YM, Park KS, Suzuki S

  • KMID: 2177908
  • J Korean Diabetes Assoc.
  • 2000 Apr;24(2):202-215.
BACKGROUND: Although genetic disorder in diabetes mellitus (DM) is not well understood, it has been suggested that the maternally inherited mitochondrial DNA which does not follow the Mendel's laws is...
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Effect of Ovariectomy and Genistein on Hepatic Mitochondrial Function

Lee YM, Jung MH, Lee YS, Song J

  • KMID: 2269803
  • Korean J Nutr.
  • 2004 Nov;37(9):786-793.
Women with menopause or rats with ovariectomy is associated with increased body weight, body fat and insulin resistance, which are components of metabolic syndrome. Increased prevalence of metabolic syndrome after...
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Interaction of Sodium Selenite on Neurotoxicity Induced by Methylmercuric Chloride

Park JS, Lee HM, Chung Y, Shin DC, Roh JH, Moon YH

  • KMID: 2282585
  • Korean J Prev Med.
  • 1992 Mar;25(1):13-25.
This study was conducted to investigate the mechanism of protective effect by sodium selenite in Methylmercuric chloride neurotoxicity, increasing intracellular Ca2+ concentration of the neuron. Methylmercuric chloride of 3 mg/kg...
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