- Dual-Blocking of PI3K and mTOR Improves Chemotherapeutic Effects on SW620 Human Colorectal Cancer Stem Cells by Inducing Differentiation
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Kim MJ, Koo JE, Han GY, Kim B, Lee YS, Ahn C, Kim CW
- KMID: 2363495
- J Korean Med Sci.
- 2016 Mar;31(3):360-370.
- doi: 10.3346/jkms.2016.31.3.360
Cancer stem cells (CSCs) have tumor initiation, self-renewal, metastasis and chemo-resistance properties in various tumors including colorectal cancer. Targeting of CSCs may be essential to prevent relapse of tumors after... -
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- Proliferation of Toxoplasma gondii Suppresses Host Cell Autophagy
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Lee YJ, Song HO, Lee YH, Ryu JS, Ahn MH
- KMID: 1715701
- Korean J Parasitol.
- 2013 Jun;51(3):279-287.
- doi: 10.3347/kjp.2013.51.3.279
Autophagy is a process of cytoplasmic degradation of endogenous proteins and organelles. Although its primary role is protective, it can also contribute to cell death. Recently, autophagy was found to... -
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- Cap-independent protein translation is initially responsible for 4-(N-methylnitrosamino)-1-(3-pyridyl)-butanone (NNK)-induced apoptosis in normal human bronchial pithelial cells
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Moon SH, Kim HW, Kim JS, Park JH, Kim H, Eu GJ, Cho HS, Kang GM, Lee KH, Cho MH
- KMID: 1093633
- J Vet Sci.
- 2004 Dec;5(4):369-378.
Evidences show that eukaryotic mRNAs can perform protein translation through internal ribosome entry sites (IRES). 5'-Untranslated region of the mRNA encoding apoptotic protease-activating factor 1 (Apaf-1) contains IRES, and, thus,... -
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- Short-term Efficacy of Topical Immunosuppressive Agents on the Survival of Cultivated Allo-Conjunctival Equivalents
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Shin YJ, Kim MK, Oh JY, Wee WR, Lee JH, Ko JH, Lee HJ, Lee JL, Min BM, Sohn YS
- KMID: 1099007
- Korean J Ophthalmol.
- 2008 Jun;22(2):123-129.
- doi: 10.3341/kjo.2008.22.2.123
PURPOSE: To investigate the short-term efficacy of topical immunosuppressive agents on the survival of cultivated allo-conjunctival equivalents. METHODS: Twenty-five eyes of New Zealand white rabbits were included. Temporal... -
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