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Mechanism of the Potentiating Effect of Secretin-CCK in Rat Pancreas

Lee DK, Kim JM, Kwon SO, Park KS, Chung JB, Kang JK, Kim KH

  • KMID: 2143777
  • Korean J Gastroenterol.
  • 1997 Mar;29(3):380-393.
BACKGROUND/AIMS: The rnechanism of secretin and CCK potentiation effect was evaluated in the dispersed pancreatic acini of rat. METHODS: To observe the presence of potentiating effect of secretin and insulin...
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The Effects of Silica Nanoparticles in Macrophage Cells

Kim S, Jang J, Kim H, Choi H, Lee K, Choi IH

Silica nanoparticles, which are applicable in many industrial fields, have been reported to induce cellular changes such as cytotoxicity in various cells and fibrosis in lungs. Because the immune system...
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The Role of Intracellular Ca2+ in Inhibiting Somatostatin-Induced Pancreatic Amylase Release

Rhie DJ, Kim HW, Song IY, Yi SY, Yoon SH, Hahn SJ, Sim SS, Kim MS, Jo YH

  • KMID: 2304684
  • Korean J Gastroenterol.
  • 1998 Dec;32(6):782-791.
BACKGROUND/AIMS: We previously found that somotostatin (SS) inhibited amylase release partly by inhibiting basal cellular cAMP formation in pancreatic acini. In the present study, we verified the effect of SS...
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Effect of Gabexate Mesilate on Exocrine Pancreatic Secreation in Rats

Kim SJ, Yoon CM, Choi SK, Kim HS, Cho CY, Rew JS

  • KMID: 2304703
  • Korean J Gastroenterol.
  • 1998 Sep;32(3):376-382.
BACKGROUND AND AIMS: Gabexate mesilate, a serine protease inhibitor, is a synthetic compound which is not antigenic and diffuses easily. We have investigated the effect of gabexate mesilate on exocrine...
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The MicroRNA hsa-let-7g Promotes Proliferation and Inhibits Apoptosis in Lung Cancer by Targeting HOXB1

Cui F, Zhou Q, Xiao K, Ma S

PURPOSE: The goal of this study was to explore the effects of hsa-let-7g on cell proliferation and apoptosis, and elucidate its role in lung cancer development. MATERIALS AND METHODS: The expression...
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Effects of cholecystokinin octapeptide on neuronal activities in the rat nucleus tractus solitarius

Rhim H, Park CW

  • KMID: 1917020
  • Korean J Physiol Pharmacol.
  • 2000 Aug;4(4):275-281.
Cholecystokinin (CCK) is a gastrointestinal hormone which plays an important role in satiety and gastric motility. It is also widely distributed throughout the central nervous system, where it appears to be involved in...
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Effect of Somatostatin on Cholecystokinin-Induced Amylase Release in Rat Pancreatic Acini

Rhie DJ, Choi WS, Yi SY, Yoon SH, Hahn SJ, Sim SS, Kim MS, Jo YH

  • KMID: 2304683
  • Korean J Gastroenterol.
  • 1998 Dec;32(6):773-781.
BACKGROUND/AIMS: The inhibitory effect of somatostatin (SS) on cholecystokinin (CCK)-induced amylase release and the role of intracellular cAMP in this process were investigated. METHODS: Pancreatic acini were isolated from rat pancreas...
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Contractile Effects of Cholecystokinin on the Muscle Strips of Gallstone Disease

Rew JS, Choi SK, Kim SJ, Yoon CM, Kim HJ

  • KMID: 2275029
  • Chonnam Med J.
  • 1997 Dec;33(2):213-220.
Cholecystokinin(CCK), a hormone and potential neurotransmitter that is released after meals, plays an important role in the control of gallbladder(GB) contractility. Decreased contractility of the GB is believed as...
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Knockdown of LncRNA H19 Relieves LPS-Induced Damage by Modulating miR-130a in Osteoarthritis

Hu Y, Li S, Zou Y

PURPOSE: Osteoarthritis (OA) is a commonly occurring illness without a definitive cure, at present. Long non-coding RNAs (lncRNAs) have been widely confirmed to be involved in the modulation of OA...
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Mechanism of Action of Cholecystokinin on Colonic Motility in Isolated, Vascularly Perfused Rat Colon

Ko BS, Han JH, Jeong JI, Chae HB, Park SM, Youn SJ, Lee KY

  • KMID: 2326192
  • J Neurogastroenterol Motil.
  • 2011 Jan;17(1):73-81.
BACKGROUND/AIMS: It is generally believed that cholecystokinin (CCK) stimulates colonic motility, although there are controversial reports. It has also been suggested that postprandial peptide YY (PYY) release is CCK-dependent. Using...
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The Effects of Mistletoe Extract and Anti-cancer Drugs on the Apoptosis of Gastric Cancer Cells

Lee YJ, Heo SH, Shin DG, Kang SK, Kim IM, Kim TH

  • KMID: 2372877
  • J Korean Gastric Cancer Assoc.
  • 2008 Sep;8(3):120-128.
PURPOSE: Mistletoe extract was widely used for cancer treatment as complementary or alternative therapy in European area from early twenty century. It is currently used as alternative anti-cancer remedy by...
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Effects of Free Anthraquinones Extract from the Rhubarb on Cell Proliferation and Accumulation of Extracellular Matrix in High Glucose Cultured-Mesangial Cells

Wang J, Fang H, Dong B, Wang D, Li Y, Chen X, Chen L, Wei T, Wei Q

Diabetic nephropathy (DN) is the leading cause of end-stage failure of the kidney, but the efficacy of currently available strategies for the prevention of DN remains unsatisfactory. In this study,...
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RPS15a Silencing Suppresses Cell Proliferation and Migration of Gastric Cancer

Shi D, Liu J

PURPOSE: Information on the possible role of the ribosomal protein S15a (RPS15a) in gastric cancer is scarce. The aim of this study was to evaluate the impact of RPS15a gene...
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miR-379 Inhibits Cell Proliferation, Invasion, and Migration of Vascular Smooth Muscle Cells by Targeting Insulin-Like Factor-1

Li K, Wang Y, Zhang A, Liu B, Jia L

PURPOSE: MicroRNAs are small non-coding RNAs that play important roles in vascular smooth muscle cell (VSMC) function. This study investigated the role of miR-379 on proliferation, invasion, and migration of...
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DAMGO, a micro-opioid agonist and cholecystokinin-octapeptide have dual modulatory effects on capsaicin-activated current in rat dorsal root ganglion neurons

Eun SY, Kim J, Lee J, Jung SJ, Park JM, Park YK, Kim D, Kim SJ, Kwak J, Kim J

  • KMID: 1606841
  • Korean J Physiol Pharmacol.
  • 2001 Feb;5(1):71-78.
Capsaicin, a pungent ingredient of hot pepper, elicits an intense burning pain when applied cutaneously and intradermally. Activation of capsaicin-gated channel in. C-type dorsal root ganglion (DRG) neurons produces nonselective cationic currents. Although...
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Comparative Analysis about the Effect of Isolated Phosphatidylcholine and Sodium Deoxycholate for the Viability of Adipocyte

Rha EY, Kang JA, Lee JH, Oh DY, Seo JW, Moon SH, Ahn ST, Rhie JW

  • KMID: 2322268
  • J Korean Soc Plast Reconstr Surg.
  • 2010 Sep;37(5):531-534.
PURPOSE: Lipobean(R)s, widely used in lipodissolving techniques, contain phosphatidylcholine and sodium deoxycholate as its main substances. They have been approved only as medication for liver disease by the FDA. However,...
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What's the Clinical Implications of the Overactive Gallbladder?

Kim MH, Kim I, Park DH, Park SH, Lee SS, Park JS, Jeong SH, Hwang CY, Kim KP, Seo DW, Lee SK, Min YI

  • KMID: 2304982
  • Korean J Gastrointest Motil.
  • 2002 Jun;8(1):37-43.
BACKGROUND/AIMS: At present, the gallbladder dysfunction implies a disorder of decreased gallbladder contractility. Other motor disorder such as overactive gallbladder which shows excessive contraction cannot be excluded in the motility...
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The Effect of Nitric Oxide on Gallbladder Motility

Hong SC, Chang KC

  • KMID: 2244446
  • Korean J Hepatobiliary Pancreat Surg.
  • 1999 Feb;3(1):11-18.
BACKGROUND/AIM: Abnormality in GB motility is related with many gallbladder diseases including GB stone. Gallbladder motility is controlled by both hormonal and neural mechanisms. CCK, gastrin, motilin play a role...
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Expression and Function of Plexin A1 in Rheumatoid Synoviocytes

Yoon HJ, Kim HS, Kwok SK, Cho CS, Kim WU

Objective: To investigate the expression and function of plexin A1, a transmembrane protein involving cell survival and cell-to cell interaction, in the rheumatoid synoviocytes. Methods: Immunohistochemical staining using anti-plexin A1 antibody...
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The Long Noncoding RNA NEAT1 Targets miR-34a-5p and Drives Nasopharyngeal Carcinoma Progression via Wnt/β-Catenin Signaling

Ji Y, Wang M, Li X, Cui F

PURPOSE: Long noncoding RNA nuclear paraspeckle assembly transcript 1 (NEAT1) has been deemed an oncogene in many human cancers. However, the underlying mechanism of NEAT1 in nasopharyngeal carcinoma (NPC) progression...
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