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Spontaneous Formation and Action of Cyclic Nucleotides in Gastric Smooth Muscle of Cats

Sim SS, Chon JS, Baek HJ, Rhie DJ, Yoon SH, Hahn SJ, Jo YH, Kim MS

  • KMID: 1547509
  • Korean J Gastroenterol.
  • 1997 Dec;30(6):721-729.
No abstract available.
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Comparative Analysis of Phospholipase D2 Localization in the Pancreatic Islet of Rat and Guinea Pig

Ryu GR, Kim MJ, Song CH, Min DS, Rhie DJ, Yoon SH, Hahn SJ, Kim MS, Jo YH

  • KMID: 2285289
  • Korean J Physiol Pharmacol.
  • 2003 Aug;7(4):211-216.
To examine the localization pattern of phospholipase D2 (PLD2) in the pancreatic islet (the islet of Langerhans) depending on species, we conducted a morphological experiment in the rat and guinea...
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Altered Secretory Pattern of Pancreatic Enzymes and Gastrointestinal Hormones in Streptozotocin-induced Diabetic Rats

Kim MJ, Ryu GR, Yi SY, Min DS, Rhie DJ, Yoon SH, Hahn SJ, Kim MS, Jo YH

  • KMID: 1615198
  • Korean J Physiol Pharmacol.
  • 2002 Dec;6(6):311-317.
This study was performed to investigate the pancreatic exocrine dysfunction in streptozotocin- induced diabetic rats. Changes in pancreatic enzymes secretion and in pancreatic enzymes content were observed. The output and...
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Effect of Fluoxetine on the Induction of Long-term Potentiation in Rat Frontal Cortex

Kim HS, Kim HS, Hahn SJ, Kim MJ, Yoon SH, Jo YH, Kim MS, Rhie DJ

  • KMID: 1611484
  • Korean J Physiol Pharmacol.
  • 2004 Dec;8(6):295-300.
Serotonin (5-hydroxytroptamine, 5-HT) has been shown to affect the induction of long-term potentiation (LTP) in the cortex such as the hippocampus, the visual cortex and the prefrontal cortex. Fluoxetine, as...
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The Role of Intracellular Ca2+ in Inhibiting Somatostatin-Induced Pancreatic Amylase Release

Rhie DJ, Kim HW, Song IY, Yi SY, Yoon SH, Hahn SJ, Sim SS, Kim MS, Jo YH

  • KMID: 2304684
  • Korean J Gastroenterol.
  • 1998 Dec;32(6):782-791.
BACKGROUND/AIMS: We previously found that somotostatin (SS) inhibited amylase release partly by inhibiting basal cellular cAMP formation in pancreatic acini. In the present study, we verified the effect of SS...
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Regulation of Protein Kinase in KCl-induced Contraction of Cat Gastric Smooth Muscle

Kim MS, Jo YH, Yoon SH, Hahn SJ, Sim SS, Shim HS, Rhie DJ, Kim SR

  • KMID: 2304693
  • Korean J Gastroenterol.
  • 1998 Sep;32(3):290-297.
BACKGROUND AND AIMS: Smooth muscle contraction and relaxation are suggested to be modulated by intracellular Ca2+, protein kinases and tyrosine kinases. To investigate whether protein kinases are invelved in the...
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Open channel block of Kv1.4 potassium channels by aripiprazole

Park J, Cho KH, Lee HJ, Choi JS, Rhie DJ

Aripiprazole is a quinolinone derivative approved as an atypical antipsychotic drug for the treatment of schizophrenia and bipolar disorder. It acts as with partial agonist activities at the dopamine D2...
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Effects of Vanadate and Pervanadate on Contraction of Cat Gastric Smooth Muscle

Sim SS, Choi HB, Shim HS, Rhie DJ, Hahn SJ, Yoon SH, Kim MS, Jo YH

  • KMID: 2084877
  • Korean J Gastroenterol.
  • 1999 Jan;33(1):1-10.
BACKGROUND/AIMS: Activated mammalian cells produce the reactive oxygen species from oxygen and they convert vanadate into pervanadate. The aim of the present study was to compare the contactile mechanisms of...
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The Development of Phasic and Tonic Inhibition in the Rat Visual Cortex

Jang HJ, Cho KH, Park SW, Kim MJ, Yoon SH, Rhie DJ

Gamma-aminobutyric acid (GABA)-ergic inhibition is important in the function of the visual cortex. In a previous study, we reported a developmental increase in GABAA receptor-mediated inhibition in the rat visual...
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Effects of Serotonin on the Induction of Long-term Depression in the Rat Visual Cortex

Jang HJ, Cho KH, Park SW, Kim MJ, Yoon SH, Rhie DJ

Long-term potentiation (LTP) and long-term depression (LTD) have both been studied as mechanisms of ocular dominance plasticity in the rat visual cortex. In a previous study, we suggested that a...
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Layer-specific serotonergic induction of long-term depression in the prefrontal cortex of rats

Shin D, Cho KH, Joo K, Rhie DJ

Layer 2/3 pyramidal neurons (L2/3 PyNs) of the cortex extend their basal dendrites near the soma and as apical dendritic tufts in layer 1, which mainly receive feedforward and feedback...
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Electrophysiological and Morphological Classification of Inhibitory Interneurons in Layer II/III of the Rat Visual Cortex

Rhie DJ, Kang HY, Ryu GR, Kim MJ, Yoon SH, Hahn SJ, Min DS, Jo YH, Kim MS

  • KMID: 1607516
  • Korean J Physiol Pharmacol.
  • 2003 Dec;7(6):317-323.
Interneuron diversity is one of the key factors to hinder understanding the mechanism of cortical neural network functions even with their important roles. We characterized inhibitory interneurons in layer II/III...
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Analysis of Basic Medicine-Related Questions in the Korean Medical Licensing Examination (2016–2018)

Kook H, Oh SO, Rhie DJ, Kee SH, Juhnn YS

Basic medical education is important for developing the competencies of medical doctors, and it includes basic biomedical sciences, preventive medicine, medical ethics, and clinical science. This study aimed to reveal...
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Altered Cholecystokinin-induced Calcium Signal in Streptozotocin-induced Diabetic Rat Pancreatic Acini

Kim MJ, Ryu GR, Sung JH, Min DS, Rhie DJ, Yoon SH, Hahn SJ, Jo YH, Kim MS

  • KMID: 1066043
  • Korean J Gastroenterol.
  • 2003 Dec;42(6):519-526.
BACKGROUND/AIMS: Pancreatic acini of streptozotocin (STZ)-induced diabetic rats release amylase less than normal acini on cholecystokinin (CCK) stimulation. Pancreatic enzyme secretion has been closely related to the intracellular calcium...
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Effect of Somatostatin on Cholecystokinin-Induced Amylase Release in Rat Pancreatic Acini

Rhie DJ, Choi WS, Yi SY, Yoon SH, Hahn SJ, Sim SS, Kim MS, Jo YH

  • KMID: 2304683
  • Korean J Gastroenterol.
  • 1998 Dec;32(6):773-781.
BACKGROUND/AIMS: The inhibitory effect of somatostatin (SS) on cholecystokinin (CCK)-induced amylase release and the role of intracellular cAMP in this process were investigated. METHODS: Pancreatic acini were isolated from rat pancreas...
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Enhancement of GluN2B Subunit-Containing NMDA Receptor Underlies Serotonergic Regulation of Long-Term Potentiation after Critical Period in the Rat Visual Cortex

Joo K, Rhie DJ, Jang HJ

Serotonin [5-hydroxytryptamine (5-HT)] regulates synaptic plasticity in the visual cortex. Although the effects of 5-HT on plasticity showed huge diversity depending on the ages of animals and species, it has...
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Regulation of the contraction induced by emptying of intracellular Ca2+ stores in cat gastric smooth muscle

Baek HJ, Sim SS, Rhie DJ, Yoon SH, Hahn SJ, Jo YH, Kim MS

  • KMID: 1982597
  • Korean J Physiol Pharmacol.
  • 2000 Apr;4(2):113-120.
To investigate the mechanism of smooth muscle contraction induced by emptying of intracellular Ca2+ stores, we measured isometric contraction and 45Ca2+ influx. CaCl2 increased Ca2+ store emptying- induced contraction in dose-dependent manner, but...
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Involvement of Spontaneously Formed Cyclic Nucleotides in Cat Gastric Muscle Relaxation

Sim SS, Baek HJ, Rhie DJ, Yoon SH, Hahn SJ, Jo YH, Kim MS

  • KMID: 2285221
  • Korean J Physiol Pharmacol.
  • 1999 Jun;3(3):275-282.
Muscle strips and muscle cells from cat stomach were used to investigate whether spontaneously formed cyclic nucleotides were involved in the inhibition of gastric smooth muscle contraction. A phosphodiesterase inhibitor, 3-isobutyl-1-methylxanthine (IBMX), increased the...
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Efffects of Fluoxetine on ATP-induced Calcium Signaling in PC12 Cells

Lee YM, Kim HJ, Hong SH, Kim MJ, Min DS, Rhie DJ, Kim MS, Jo YH, Hahn SJ, Yoon SH

  • KMID: 1517038
  • Korean J Physiol Pharmacol.
  • 2004 Feb;8(1):57-63.
Fluoxetine, a widely used anti-depressant compound, has several additional effects, including blockade of voltage-gated ion channels. We examined whether fluoxetine affects ATP-induced calcium signaling in PC12 cells by using fura-2-based...
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Developmental Switch of the Serotonergic Role in the Induction of Synaptic Long-term Potentiation in the Rat Visual Cortex

Park SW, Jang HJ, Cho KH, Kim MJ, Yoon SH, Rhie DJ

Synaptic long-term potentiation (LTP) and long-term depression (LTD) have been studied as mechanisms of ocular dominance plasticity in the rat visual cortex. Serotonin (5-hydroxytryptamine, 5-HT) inhibits the induction of LTP...
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