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Thromboxane A2 Receptor (T924C) Polymorphism is Associated with Lower Pulmonary Function in Korean Children with Asthma

  • KMID: 2299780
  • Korean J Asthma Allergy Clin Immunol.
  • 2005 Mar;25(1):34-38.
BACKGROUND: Thromboxane A2 and its receptor (TBXA2R) are involved in the constriction of vascular and respiratory smooth muscle, which may play a role in the thickening and remodeling of the...
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Role of Prostaglandin D2 in the Pathogenesis of Asthma

  • KMID: 2299463
  • Korean J Asthma Allergy Clin Immunol.
  • 2012 Sep;32(3):144-149.
Prostaglandin D2 is a major lipid mediator released from activated mast cells of which metabolite 9alpha,11beta-prostaglandin F2 are used as a biomarker of mast cell activation in various type of...
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PGF2 alpha causes bronchoconstriction and pulmonary vasoconstriction via thromboxane receptors in rat lung

Kang KH, Shim JJ, Banerjee M, Newman JH

  • KMID: 1038466
  • Korean J Intern Med.
  • 1996 Jan;11(1):74-81.
We determined the vascular and airway effects of PGF2 alpha and its mechanism of action on isolated-perfused lungs of rats were isolated and perfused at 50 ml/kg/min with Krebs-Henseleit bicarbonate...
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Nicotine in High Concentration Causes Contraction of Isolated Strips of Rabbit Corpus Cavernosum

Nguyen HB, Lee SY, Park SH, Han JH, Lee MY, Myung SC

It is well known that cigarette smoke can cause erectile dysfunction by affecting the penile vascular system. However, the exact effects of nicotine on the corpus cavernosum remains poorly understood....
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Stroke Update 2011: New Antithrombotics

Seo KD, Lee KY

  • KMID: 2288709
  • Korean J Stroke.
  • 2012 Aug;14(2):62-66.
Several new antithrombotic drugs have been developed and approved to use in clinical practice recently. Dabigatran, a direct thrombin inhibitor, and rivaroxaban, a factor Xa inhibitor, have been approved in...
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Thromboxane A2 modulates migration, proliferation, and differentiation of adipose tissue-derived mesenchymal stem cells

Yun DH, Song HY, Lee MJ, Kim MR, Kim MY, Lee JS, Kim JH

Prostanoid metabolites are key mediators in inflammatory responses, and accumulating evidence suggests that mesenchymal stem cells (MSCs) can be recruited to injured or inflamed tissues. In the present study, we...
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rBMSCs/ITGA5B1 Promotes Human Vascular Smooth Muscle Cell Differentiation via Enhancing Nitric Oxide Production

Zhang Y, Ding J, Xu C, Yang H, Xia P, Ma S, Chen H

BACKGROUND AND OBJECTIVES: Previous studies have shown that integrins alpha5beta1 (ITGA5B1) gene-modified rat bone marrow mesenchymal stem cells (rBMSCs) could prevent cell anoikis and increase the nitric oxide (NO) production....
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