- Role of Prostaglandin D2 in the Pathogenesis of Asthma
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- KMID: 2299463
- Korean J Asthma Allergy Clin Immunol.
- 2012 Sep;32(3):144-149.
Prostaglandin D2 is a major lipid mediator released from activated mast cells of which metabolite 9alpha,11beta-prostaglandin F2 are used as a biomarker of mast cell activation in various type of... -
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- Prostaglandin E2 Receptors on Upper Respiratory Tract
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Kim JK
- KMID: 2074132
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2009 Jul;52(7):553-559.
- doi: 10.3342/kjorl-hns.2009.52.7.553
Prostaglandin (PG) E2 exerts its actions by acting on a group of G-protein-coupled receptors (GPCRs). GPCRs responding to PGE2 consist of four subtypes namely E-prostanoid 1 (EP1), E-prostanoid 2 (EP2),... -
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- Prostaglandin D2 and TH2 Inflammation in the Pathogenesis of Bronchial Asthma
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Arima M, Fukuda T
- KMID: 1036144
- Korean J Intern Med.
- 2011 Mar;26(1):8-18.
- doi: 10.3904/kjim.2011.26.1.8
Prostaglandin D2 (PGD2) is a major prostanoid, produced mainly by mast cells, in allergic diseases, including bronchial asthma. PGD2-induced vasodilatation and increased permeability are well-known classical effects that may be... -
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- Lubiprostone Increases Small Intestinal Smooth Muscle Contractions Through a Prostaglandin E Receptor 1 (EP1)-mediated Pathway
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Chan WW, Mashimo H
- KMID: 2326230
- J Neurogastroenterol Motil.
- 2013 Jul;19(3):312-318.
BACKGROUND/AIMS: Lubiprostone, a chloride channel type 2 (ClC-2) activator, was thought to treat constipation by enhancing intestinal secretion. It has been associated with increased intestinal transit and delayed gastric emptying.... -
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- Effect of Prostaglandin E2 on Gel-forming Mucin Secretion in Normal Human Nasal Epithelial Cells
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Kim JK, Kim CH, Kim K, Jang HV, Kim HJ, Yoon JH
- KMID: 2276604
- Korean J Otolaryngol-Head Neck Surg.
- 2006 Mar;49(3):307-312.
BACKGROUND AND OBJECTIVES: Recently, Prostaglandin E2 (PGE2) was found to induce MUC5AC production via an agonist of E-prostanoid (EP2/EP4), but not EP1/EP3, in normal human airway epithelium. However, the receptor... -
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- Prostagladin E Receptor II and IV Increase the Expression of Martrix Metalloproteinase-7 in PC (Prostate Cancer)-3 Cells
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Kim TH, Kim YS, Myoung SC, Lee JH, Won EH
- KMID: 2293493
- Korean J Urol.
- 2004 May;45(5):478-484.
PURPOSE: The effects of PGE2 receptors (EP1, 2, 3, 4) on the proliferation of prostate cancer cells are still unclear. The degradation of the basement membrane by MMP-2, 7, 9... -
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- The Effects of Selective Cyclooxygenase-2 Inhibitor and Prostaglandin E2 Receptor Agonists on the Endothelin Axis of Prostate Cancer Cells
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Kim TH, Kim YS, Myung SC, Lee SW, Won EH, Kim TH
- KMID: 2294201
- Korean J Urol.
- 2006 Feb;47(2):195-200.
- doi: 10.4111/kju.2006.47.2.195
PURPOSE: The enhanced expression of the cyclooxygenase-2 (COX-2), prostaglandin E2 receptor (EPs) and endothelin-1 (ET-1) axis is known to play a significant role in the development and progression of several... -
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- Prostaglandin F receptor expression in intrauterine tissues of pregnant rats
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Anadol E, Kanca H, Yar AS, Helvacioglu F, Menevse S, Calguner E, Erdogan D
- KMID: 1737618
- J Vet Sci.
- 2014 Mar;15(1):125-131.
- doi: 10.4142/jvs.2014.15.1.125
In this investigation, we studied the expression and localization of rat prostaglandin F (FP) receptor in uterine tissues of rats on gestational Days 10, 15, 18, 20, 21, 21.5 and... -
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- Inhibitory G proteins and their receptors: emerging therapeutic targets for obesity and diabetes
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Kimple ME, Neuman JC, Linnemann , Casey PJ
- KMID: 2155367
- Exp Mol Med.
- 2014 Jun;46(6):e102.
- doi: 10.1038/emm.2014.40
The worldwide prevalence of obesity is steadily increasing, nearly doubling between 1980 and 2008. Obesity is often associated with insulin resistance, a major risk factor for type 2 diabetes mellitus... -
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- The Prostaglandin E Receptor Agonists Increase Granulocyte Macrophage Colony-Stimulating Factor in Prostate Cancer Cells
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Kim TH, Kim YS, Myung SC, Lee DH, Won EH, Lee SY
- KMID: 2293239
- Korean J Urol.
- 2004 Dec;45(12):1272-1278.
PURPOSE: The predilection for prostate carcinoma cells to metastasize to bone suggests the hypothesis that bone and/or bone marrow-derived factors may promote prostate carcinoma cell growth and/or their survival. To... -
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- Paricalcitol attenuates lipopolysaccharide-induced inflammation and apoptosis in proximal tubular cells through the prostaglandin Eâ‚‚ receptor EP4
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Hong YA, Yang KJ, Jung SY, Chang YK, Park CW, Yang CW, Kim SY, Hwang HS
- KMID: 2384617
- Kidney Res Clin Pract.
- 2017 Jun;36(2):145-158.
- doi: 10.23876/j.krcp.2017.36.2.145
BACKGROUND: Vitamin D is considered to exert a protective effect on various renal diseases but its underlying molecular mechanism remains poorly understood. This study aimed to determine whether paricalcitol attenuates... -
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- Lysophosphatidic acid receptor 2 and Gi/Src pathway mediate cell motility through cyclooxygenase 2 expression in CAOV-3 ovarian cancer cells
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Jeong KJ, Park SY, Seo JH, Lee KB, Choi WS, Han JW, Kang JK, Park CG, Kim YK, Lee HY
- KMID: 1072941
- Exp Mol Med.
- 2008 Dec;40(6):607-616.
- doi: 10.3858/emm.2008.40.6.607
Lysophosphatidic acid (LPA) is a bioactive phospholipids and involves in various cellular events, including tumor cell migration. In the present study, we investigated LPA receptor and its transactivation to EGFR... -
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