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Significance of Intratumoral Fibrosis in Clear Cell Renal Cell Carcinoma

Joung JW, Oh HK, Lee SJ, Kim YA, Jung HJ

BACKGROUND: Intratumoral fibrosis (ITF) is a frequent histologic finding in solid organ tumors. Renal cell carcinoma (RCC) is a highly vascularized tumor with different shapes and degrees of ITF and...
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The Differential Expression of Lysyl Oxidase in Keratoacanthoma and Squamous Cell Carcinoma

Nam HM, Choi KH, Park K, Park SD

  • KMID: 2301656
  • Korean J Dermatol.
  • 2012 Mar;50(3):220-226.
BACKGROUND: Because keratoacanthoma (KA) and squamous cell carcinoma (SCC) are very similar with respect to clinical and histological features but are different with respect to prognosis and treatment, it is...
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The Role of the Lysyl Oxidases in Tissue Repair and Remodeling: A Concise Review

Cai L, Xiong X, Kong X, Xie J

Tissue injury provokes a series of events containing inflammation, new tissue formation and tissue remodeling which are regulated by the spatially and temporally coordinated organization. It is an evolutionarily conserved,...
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Changes of Gene Expression in NIH3T3 Cells Exposed to Osmotic and Oxidative Stresses

Lee JS, Jung JH, Kim TH, Seo JS

  • KMID: 2166167
  • Genomics Inform.
  • 2004 Jun;2(2):67-74.
Cells consistently face stressful conditions, which cause them to modulate a variety of intracellular processes and adapt to these environmental changes via regulation of gene expression. Hyperosmotic and oxidative stresses...
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A Novel Association between Lysyl Oxidase Gene Polymorphism and Intracranial Aneurysm in Koreans

Hong EP, Jeon JP, Kim SE, Yang JS, Choi HJ, Kang SH, Cho YJ

PURPOSE: Lysyl oxidase (LOX) controls the cross-linking and maturation of elastin and collagen fibers. In this study, we investigated the association between LOX gene polymorphisms and intracranial aneurysm (IA) formation...
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A Catalogue of Gene Expression Difference in Biliary Cirrhosis due to Biliary Atresia Using Differential Expressed Sequence Tags(EST) Screening

Choe BH, Lee HM, Kim MK, Kim JC

  • KMID: 1946275
  • J Korean Pediatr Soc.
  • 2000 Jan;43(1):60-69.
PURPOSE: Extrahepatic biliary atresia is the most common indication for liver transplantation in children, but the etiology of this disorders remains unknown. It would be very signficant to identify genes...
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Conditional knockout of brca1/2 and p53 in mouse ovarian surface epithelium: Do they play a role in ovarian carcinogenesis?

Kim KY, Park DW, Jeung EB, Choi KC

Alterations of genes are known to be critical for the induction of tumorigenesis, but the mechanism of ovarian carcinogenesis is little understood and remains to be elucidated. In this study,...
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