- P53 expression in hepatocellular carcinoma: influence on the radiotherapeutic response of the hepatocellular carcinoma
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Lee YR, Park SY
- KMID: 2351022
- Clin Mol Hepatol.
- 2015 Sep;21(3):230-231.
- doi: 10.3350/cmh.2015.21.3.230
No abstract available. -
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- p53 protein overexpression in astrocytic neoplasms
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Cho MY, Jung SH, Kim TS
- KMID: 699864
- Yonsei Med J.
- 1995 Dec;36(6):521-526.
- doi: 10.3349/ymj.1995.36.6.521
Abnormalities of the p53 gene are the most common molecular change in human cancer. In the central nervous system, mutant p53 gene is frequently identified in the tumors with astrocytic... -
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- p53 and DNA-dependent protein kinase catalytic subunit independently function in regulating actin damage-induced tetraploid G1 arrest
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Chae HD, Kim SY, Park SE, Kim J, Shin DY
- KMID: 1245266
- Exp Mol Med.
- 2012 Mar;44(3):236-240.
- doi: 10.3858/emm.2012.44.3.018
We previously reported that the p53 tumor suppressor protein plays an essential role in the induction of tetraploid G1 arrest in response to perturbation of the actin cytoskeleton, termed actin... -
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- Expression of pRb, p53, p16 and Cyclin D1 and Their Clinical Implications in Urothelial Carcinoma
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Lee K, Jung ES, Choi YJ, Lee KY, Lee A
- KMID: 2157848
- J Korean Med Sci.
- 2010 Oct;25(10):1449-1455.
- doi: 10.3346/jkms.2010.25.10.1449
The aim of this study was to assess immunohistochemical expression of p53, pRb, p16, and cyclin D1, alone or in combination, as prognostic indicators and to investigate their correlation with... -
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- Immunohistochemical Expression of Bcl-2, Bcl-xL, Bax, p53 Proteins in Gastric Adenoma and Adenocarcinoma
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Lee DS, Kang SB, Baek JT, Nam SW, Lee KM, Ahn BM, Lee EH, Han SW, Chung IS
- KMID: 772786
- Korean J Gastroenterol.
- 2005 Jun;45(6):394-400.
BACKGROUND/AIMS: The aim of this study was to investigate the immunohistochemical expression of bcl-2, bcl-xL, bax, and p53 proteins according to the pathological parameters such as grade of dysplasia,... -
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- Cyclooxygenase-2 and p53 Expression as Prognostic Indicators in Conventional Renal Cell Carcinoma
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Cho DS, Joo HJ, Oh DK, Kang JH, Kim YS, Lee KB, Kim SJ
- KMID: 2158123
- Yonsei Med J.
- 2005 Feb;46(1):133-140.
- doi: 10.3349/ymj.2005.46.1.133
The aim of this study was to investigate the relationship of cyclooxygenase (COX) -2 and p53 expression with prognosis in patients with conventional renal cell carcinoma (RCC). Formalin-fixed, paraffin-embedded tissue... -
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- Prognostic Significance of p53 Overexpression after Hepatic Resection of Hepatocellular Carcinoma
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Sung CO, Yoo BC, Koh KC, Cho JW, Park CK
- KMID: 772790
- Korean J Gastroenterol.
- 2005 Jun;45(6):425-430.
BACKGROUND/AIMS: p53 mutation is the most common genetic abnormality in human cancers. However, although it has been reported that p53 overexpression in hepatocellular carcinoma (HCC) is associated with the... -
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- Prognostic Implications of Cyclin B1, p34cdc2, p27(Kip1) and p53 Expression in Gastric Cancer
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Kim DH
- KMID: 2158177
- Yonsei Med J.
- 2007 Aug;48(4):694-700.
- doi: 10.3349/ymj.2007.48.4.694
PURPOSE: Cell cycle progression is regulated by interactions of specific cyclins and cyclin dependent kinases (CDKs) at the G1-S and G2-M checkpoints and cell cycle deregulation plays a major role... -
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- Distinct Patterns of Cleavage and Translocation of Cell Cycle Control Proteins in CD95-induced and p53-induced apoptosis
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Park WS, Jung KC, Chung DH, Nam WD, Choi WJ, Bae Y
- KMID: 648894
- J Korean Med Sci.
- 2003 Aug;18(4):467-472.
- doi: 10.3346/jkms.2003.18.4.467
Apoptotic cell death induced by p53 occurs at a late G1 cell cycle checkpoint termed the restriction(R)point, and it has been proposed that p53-induced apoptosis causes upregulation of CD95. However,... -
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- Tissue Microarray Analysis of Fas and FasL Expressions in Human Non-small Cell Lung Carcinomas; with Reference to the p53 and bcl-2 Overexpressions
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Myong NH
- KMID: 1781759
- J Korean Med Sci.
- 2005 Oct;20(5):770-776.
- doi: 10.3346/jkms.2005.20.5.770
Lack of surface Fas expression is a main route for apoptotic resistance which is considered an important mechanism of tumorigenesis and tumor progression. Fas and FasL expressions in 110 non-small... -
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- Influence of P53 on the radiotherapy response of hepatocellular carcinoma
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Gomes AR, Abrantes A, Brito AF, Laranjo M, Casalta-Lopes JE, Goncalves , Sarmento-Ribeiro AB, Botelho MF, Tralhao JG
- KMID: 2351026
- Clin Mol Hepatol.
- 2015 Sep;21(3):257-267.
- doi: 10.3350/cmh.2015.21.3.257
BACKGROUND/AIMS: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, and it has a poor prognosis and few therapeutic options. Radiotherapy is one of the most effective forms... -
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- Human telomerase catalytic subunit (hTERT) suppresses p53-mediated anti-apoptotic response via induction of basic fibroblast growth factor
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Jin X, Beck S, Sohn YW, Kim JK, Kim SH, Yin J, Pian X, Kim SC, Choi YJ, Kim H
- KMID: 1104384
- Exp Mol Med.
- 2010 Aug;42(8):574-582.
- doi: 10.3858/emm.2010.42.8.058
Although human telomerase catalytic subunit (TERT) has several cellular functions including telomere homeostasis, genomic stability, cell proliferation, and tumorigenesis, the molecular mechanism underlying anti-apoptosis regulated by TERT remains to be... -
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- Prognostic Significance of Immunohistochemical Expression of p53 and Retinoblastoma Gene Protein (pRB) in Curatively Resected Gastric Cancer
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Song HS, Kim IH, Sohn SS, Kwon KY, Lee WS
- KMID: 1776689
- Korean J Intern Med.
- 2005 Mar;20(1):1-7.
- doi: 10.3904/kjim.2005.20.1.1
BACKGROUND: The aim of this study was to determine the prognostic significance of the expression of p53 and retinoblastoma (Rb) gene products in cases of curatively resected gastric adenocarcinoma, by... -
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- Immunohistochemical Expression of the p53 and Ki-67 Proteins in Barrett's Esophagus in Korea
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Kim CW, Lee BI, Kim BW, Kim JI, Park SH, Kim JK, Han SW, Jung IS, Sun HS, Lee AW, Lee KY
- KMID: 935210
- Korean J Gastroenterol.
- 2005 Sep;46(3):189-195.
BACKGROUND/AIMS: Barrett's esophagus is a premalignant lesion of the esophagus in which normal squamous epithelium is replaced by intestinalized columnar epithelium. In Korea, adenocarcinoma associated with Barrett's esophagus is rare... -
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- CD34 and p53 Immunohistochemical Stains Differentiate Hypocellular Myelodysplastic Syndrome (hMDS) from Aplastic Anemia and a CD34 Immunohistochemical Stain Provides Useful Survival Information for hMDS
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Cha CH, Park CJ, Chi HS, Seo EJ, Jang S, Cho YU, Lee KH, Lee JH, Lee JH, Im HJ, Seo JJ
- KMID: 2129567
- Ann Lab Med.
- 2014 Nov;34(6):426-432.
- doi: 10.3343/alm.2014.34.6.426
BACKGROUND: The presence of significant dysplasia in bone marrow (BM) aspirates helps to distinguish between hypocellular myelodysplastic syndrome (hMDS) and aplastic anemia (AA). Occasionally, diluted BM aspirates make it difficult... -
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