- Conditional knockout of brca1/2 and p53 in mouse ovarian surface epithelium: Do they play a role in ovarian carcinogenesis?
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Kim KY, Park DW, Jeung EB, Choi KC
- KMID: 1072177
- J Vet Sci.
- 2010 Dec;11(4):291-297.
- doi: 10.4142/jvs.2010.11.4.291
Alterations of genes are known to be critical for the induction of tumorigenesis, but the mechanism of ovarian carcinogenesis is little understood and remains to be elucidated. In this study,... -
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- Expression of p53 and NDP-K/nm23 in gastric carcinomas: association with metastasis and clinicopathologic parameters
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Kim KM, Lee A, Chae HS, Shim SI
- KMID: 927171
- J Korean Med Sci.
- 1995 Dec;10(6):406-413.
- doi: 10.3346/jkms.1995.10.6.406
To evaluate the role of p53 and NDP-K/nm23(nm23) protein as a prognostic factor and their relation to metastasis of cancer, we studied metastatic and nonmetastatic gastric carcinoma specimens by immunohistochemical... -
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- p53 Genetic Polymorphism of Gastric cancer in Korea
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Chung WC, Lee KM, Lee BI, Chun JS, Lee SY, Chang UI, Park SH, Yang JM, Choi KY, Chung IS
- KMID: 1782248
- Korean J Intern Med.
- 2006 Mar;21(1):28-32.
- doi: 10.3904/kjim.2006.21.1.28
BACKGROUND: Deletion or functional loss of the p53 tumor suppression gene plays a role in oncogenic transformation. The codon 72 polymorphism on exon 4 in the p53 gene produces... -
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- Immunohistochemical Expression of p53, Bcl-2, and Ki-67 Proteins in Traditional Serrated Adenomas of Colon
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Jung JH, Kwon HJ, Kim TJ, Cho HJ, Kim HK, Cheung DY, Kim JI, Kim JK
- KMID: 1711289
- Korean J Gastroenterol.
- 2013 Dec;62(6):336-343.
- doi: 10.4166/kjg.2013.62.6.336
BACKGROUND/AIMS: Serrated adenomas of the colon show mixed characteristics of both hyperplastic and adenomatous polyps. Serrated adenomas are known to progress via the serrated pathway than the adenoma-carcinoma pathway. The... -
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- Overexpressions of Cyclin B1, cdc2, p16 and p53 in Human Breast Cancer: The Clinicopathologic Correlations and Prognostic Implications
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Chae SW, Sohn JH, Kim DH, Choi YJ, Park YL, Kim K, Cho YH, Pyo JS, Kim JH
- KMID: 1777016
- Yonsei Med J.
- 2011 May;52(3):445-453.
- doi: 10.3349/ymj.2011.52.3.445
PURPOSE: The molecular mechanisms that are responsible for the initiation and progression of breast cancers are largely unknown. This study was to analyze the cyclin B1, cdc2, p53 and p16... -
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- In vivo Recombinant Adenovirus-mediated p53 Gene Therapy in a Syngeneic Rat Model for Colorectal Cancer
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Baek JH, Agarwal ML, Tubbs RR, Vladisavljevic A, Tomita H, Bukowski R, Milsom JW, Kim JM, Kwak JY
- KMID: 1778565
- J Korean Med Sci.
- 2004 Dec;19(6):834-841.
- doi: 10.3346/jkms.2004.19.6.834
The p53 gene has a significant role in controlling genomic stability of cancer. The purpose of this study was to evaluate the tumor response of allograft colorectal tumor treated with... -
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- [6]-Gingerol Induces Cell Cycle Arrest and Cell Death of Mutant p53-expressing Pancreatic Cancer Cells
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Park YJ, Wen J, Bang S, Park SW, Song SY
- KMID: 1381250
- Yonsei Med J.
- 2006 Oct;47(5):688-697.
- doi: 10.3349/ymj.2006.47.5.688
[6]-Gingerol, a major phenolic compound derived from ginger, has anti-bacterial, anti-inflammatory and anti-tumor activities. While several molecular mechanisms have been described to underlie its effects on cells in vitro and... -
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- TP53 Polymorphisms allow for genetic sub-grouping of the canine transmissible venereal tumor
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Sanchez-Servin A, Martinez S, Cordova-Alarcon E, Fajardo R
- KMID: 1726910
- J Vet Sci.
- 2009 Dec;10(4):353-355.
- doi: 10.4142/jvs.2009.10.4.353
The canine transmissible venereal tumor (CTVT) is found mainly in dogs' sexual organs. Currently, it is widely accepted that all samples of CTVT show similar histopathological characteristics and share common... -
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- TP53 Mutations in Korean Patients with Non-small Cell Lung Cancer
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Lee EB, Jin G, Lee SY, Park JY, Kim MJ, Choi JE, Jeon HS, Cha SI, Cho S, Kim CH, Park TI, Jung TH, Son JW, Park JY
- KMID: 1713952
- J Korean Med Sci.
- 2010 May;25(5):698-705.
- doi: 10.3346/jkms.2010.25.5.698
Although TP53 mutations have been widely studied in lung cancer, the majority of studies have focused on exons 5-8 of the gene. In addition, TP53 mutations in Korean patients with... -
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- Germline TP53 Mutation and Clinical Characteristics of Korean Patients With Li-Fraumeni Syndrome
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Park KJ, Choi HJ, Suh SP, Ki CS, Kim JW
- KMID: 2373577
- Ann Lab Med.
- 2016 Sep;36(5):463-468.
- doi: 10.3343/alm.2016.36.5.463
BACKGROUND: Little is known of the mutation and tumor spectrum of Korean patients with Li-Fraumeni syndrome (LFS). Owing to the rarity of LFS, few cases have been reported in Korea... -
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- Erratum: Panton-Valentine Leukocidin Positive Staphylococcus aureus Isolated from Blood in Korea
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Kim JS, Park JS, Song W, Kim HS, Cho HC, Lee KM, Kim EC
- KMID: 1781586
- Korean J Lab Med.
- 2008 Dec;28(6):498-498.
- doi: 10.3343/kjlm.2008.28.6.498
This erratum is being published to correct the printing error on page 286 of the article entitled 'Panton-Valentine leukocidin positive Staphylococcus aureus isolated from blood in Korea' by Kim JS,... -
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- Genetic Counseling Can Influence the Course of a Suspected Familial Cancer Syndrome Patient: From a Case of Li-Fraumeni Like Syndrome with a Germline Mutation in the TP53 Gene
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Hwang SM, Lee ES, Shin SH, Kong SY
- KMID: 1781585
- Korean J Lab Med.
- 2008 Dec;28(6):493-497.
- doi: 10.3343/kjlm.2008.28.6.493
We report a 26-yr-old female patient with bilateral breast cancer who was clinically diagnosed with Li-Fraumeni like syndrome (LFL) and subsequently found to have a germline mutation of the TP53... -
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