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Association between Obsessive-Compulsive Symptoms and Long-Term Cardiac Outcomes in Patients with Acute Coronary Syndrome: Effects of Depression Comorbidity and Treatment

Lee HJ, Kim JW, Kang HJ, Kim SW, Shin IS, Hong YJ, Ahn YK, Jeong MH, Yoon JS, Kim JM

OBJECTIVE: The role of obsessive-compulsive symptoms (OCS) in patients with acute coronary syndrome (ACS) is not well elucidated. This study investigated the association between OCS and the long-term prognosis of...
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Impact of Repetitive Transcranial Magnetic Stimulation with Computerized Cognitive Enhancement Training on Change in Cognitive Function of Mild Cognitive Impairment Patients : Existing, Sham Treatment Controlled, Pilot Study

Lee SE, Moon HS, Chung ST, Lee CU, Kang DW

OBJECTIVE: This study aimed to investigate the effects of repetitive transcranial magnetic stimulation (rTMS) and computerized cognitive enhancement training combined treatment on cognitive function in mild cognitive impairment (MCI) patients,...
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Treatment of Palmar Hyperhidrosis with Tap Water Iontophoresis: A Randomized, Sham-Controlled, Single-Blind, and Parallel-Designed Clinical Trial

Kim DH, Kim TH, Lee SH, Lee AY

BACKGROUND: Palmar hyperhidrosis is a common disorder of excessive sweating. A number of studies have demonstrated the effectiveness of iontophoresis in the treatment of palmar hyperhidrosis. However, controlled clinical studies...
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Efficacy of Nasal Cellulose Powder in the Symptomatic Treatment of Allergic Rhinitis: A Randomized, Double-Blind, Placebo-Controlled Trial

Manuyakorn W, Klangkalya N, Kamchaisatian W, Benjaponpita S, Sasisakulporn C, Jotikasthira W

PURPOSE: Nasal Cellulose Powder (NCP), which can prevent from binding an allergen to nasal mucosa, may reduce allergic rhinitis (AR) symptoms in dust mite-sensitized children. This study was conducted to...
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Inhibition of Allergic Response by Intranasal Selective NF-κB Decoy Oligodeoxynucleotides in a Murine Model of Allergic Rhinitis

Wee JH, Zhang YL, Rhee CS, Kim DY

PURPOSE: It remains unknown whether local inhibition of Nuclear factor-kappa B (NF-κB) could have therapeutic value in the treatment of allergic rhinitis (AR). This study aimed to evaluate the effect...
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Remote Ischemic Preconditioning Enhances the Expression of Genes Encoding Antioxidant Enzymes and Endoplasmic Reticulum Stress-Related Proteins in Rat Skeletal Muscle

Park UJ, Kim HT, Cho WH, Park JH, Jung HR, Kim MY

PURPOSE: Ischemic preconditioning (IPC), including remote IPC (rIPC) and direct IPC (dIPC), is a promising method to decrease ischemia-reperfusion (IR) injury. This study tested the effect of both rIPC and...
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Pain Management Knowledge, Attitudes, and Performance of Nurses in Long-Term Care Hospitals

Cho H, Kwon SH

PURPOSE: This study investigated long-term care hospital nurses' knowledge and practice of pain management and their attitudes towards the job with an ultimate aim to provide fundamental information for development...
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Efficacy of Ginseng Supplements on Fatigue and Physical Performance: a Meta-analysis

Bach HV, Kim J, Myung SK, Cho YA

We conducted a meta-analysis to investigate the efficacy of ginseng supplements on fatigue reduction and physical performance enhancement as reported by randomized controlled trials (RCTs). RCTs that investigated the efficacy...
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Direct vascular actions of quercetin in aorta from renal hypertensive rats

Choi S, Ryu KH, Park SH, Jun JY, Shin BC, Chung JH, Yeum CH

BACKGROUND: Chronic treatment with the dietary flavonoid quercetin is known to lower blood pressure and restore endothelial dysfunction in animal models of hypertension. This study investigated the direct effects of...
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Effect of Indacaterol on Cough and Phlegm in Chronic Obstructive Pulmonary Disease Patients: A Meta-Analysis of Five Randomized Controlled Trials

Park J, Lee JS, Rhee C, Oh YM

We investigated the effects of indacaterol on cough and phlegm in patients with stable chronic obstructive pulmonary disease (COPD). We performed a meta-analysis with five randomized controlled trials (RCTs) of...
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Munchausen Stridor-A Strong False Alarm of Anaphylaxis

Bahna SL, Oldham JL

The diagnosis of anaphylaxis is often based on reported symptoms which may not be accurate and lead to major psychosocial and financial impacts. We describe two adult patients who were...
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Placebo Effect in Clinical Trial Design for Irritable Bowel Syndrome

Shah E, Pimentel M

  • KMID: 2381168
  • J Neurogastroenterol Motil.
  • 2014 Apr;20(2):163-170.
Ongoing efforts to improve clinical trial design in irritable bowel syndrome have been hindered by high placebo response rates and ineffective outcome measures. We assessed established strategies to minimize placebo...
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Psychiatric Applications of Placebos

Sohn I, Kim I

  • KMID: 2287778
  • Korean J Psychopharmacol.
  • 2014 Apr;25(2):37-42.
As the placebo effect is inevitable in almost all types of treatment implemented in the context of the doctor-patient relationship, it would be a wise strategy to try to enhance...
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Effects of oxidative stress on endothelial modulation of contractions in aorta from renal hypertensive rats

Choi S, Shin HR, Kim SH, Lee MJ, Jun JY, Kim HL, Chung JH, Yeum CH

  • KMID: 2224282
  • Kidney Res Clin Pract.
  • 2014 Mar;33(1):19-25.
BACKGROUND: Endothelial dysfunction is linked to exaggerated production of superoxide anions. This study was conducted to examine the effects of oxidative stress on endothelial modulation of contractions in chronic two-kidney,...
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Evidence-Based, Non-Pharmacological Treatment Guideline for Depression in Korea

Park SC, Oh HS, Oh DH, Jung SA, Na KS, Lee HY, Kang RH, Choi YK, Lee MS, Park YC

Although pharmacological treatment constitutes the main therapeutic approach for depression, non-pharmacological treatments (self-care or psychotherapeutic approach) are usually regarded as more essential therapeutic approaches in clinical practice. However, there have...
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Endothelium-dependent vasodilation by ferulic acid in aorta from chronic renal hypertensive rats

Choi S, Kim HI, Park SH, Lee MJ, Jun JY, Kim HL, Chung JH, Yeum CH

  • KMID: 1426333
  • Kidney Res Clin Pract.
  • 2012 Dec;31(4):227-233.
BACKGROUND: Ferulic acid (FA) is a naturally occurring nutritional compound. Although it has been shown to have antihypertensive effects, its effects on vascular function have not been intensively established. The...
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Efficacy of Ronidazole for Treatment of Cats Experimentally Infected with a Korean Isolate of Tritrichomonas foetus

Lim S, Park SI, Ahn KS, Oh DS, Shin SS

To evaluate the efficacy of ronidazole for treatment of Tritrichomonas foetus infection, 6 Tritrichomonas-free kittens were experimentally infected with a Korean isolate of T. foetus. The experimental infection was confirmed...
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Pharmacologic and Complementary and Alternative Medicine Therapies for Irritable Bowel Syndrome

Chey WD, Maneerattaporn M, Saad R

  • KMID: 2284205
  • Gut Liver.
  • 2011 Sep;5(3):253-266.
Irritable bowel syndrome (IBS) is a chronic functional gastrointestinal disorder characterized by episodic abdominal pain or discomfort in association with altered bowel habits (diarrhea and/or constipation). Other gastrointestinal symptoms, such...
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Direct Vascular Actions of Indapamide in Aorta from Renal Hypertensive Rats

Choi S, Whi HW, Lee MJ, Jun JY, Kim HL, Chung JH, Shin HR, Oh HJ, Yeum CH

  • KMID: 2252634
  • Korean J Nephrol.
  • 2011 Sep;30(5):459-467.
PURPOSE: Thiazide diuretics exert their hypotensive efficacy through a combined vasodilator and diuretic effect. The present study was conducted to assess the inhibitory effect of thiazide diuretic, hydrochlorothiazide, and the...
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The Role of Oxygen-Derived Free Radicals in Vascular Relaxations to Pinacidil in Renal Hypertensive Rats

Choi S, Yoo IJ, Whi HW, Jun JY, Kim HI, Shin HR, Oh HJ, Chung JH, Yeum CH

  • KMID: 2080107
  • Korean J Nephrol.
  • 2010 Nov;29(6):695-701.
PURPOSE: Evidence has emerged that oxygen-derived free radicals may induce vascular relaxations via ATP-sensitive K+ (K(ATP)) channels and the level of free radicals is increased in animal models of hypertension....
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