Skip Navigation
Skip to contents
Results by Year

View Wide

Filter

ARTICLE TYPE

more+
SELECT FILTER
 
Close

PUBLICATION DATE

80 results
Display

Comparison of In Vivo Pharmacokinetics and Pharmacodynamics of Vancomycin Products Available in Korea

Kim HK, Choi SM, Kang G, Park KH, Lee DG, Park WB, Rhee SJ, Lee S, Jung SI, Jang HC

PURPOSE: Few studies have been investigated the in vivo efficacy of generic vancomycin products available outside of the United States. In this study, we aimed to compare the in vivo...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Elucidation of the pathophysiology of intradialytic muscle cramps: pharmacokinetics applied to translational research

Atkinson A

In the conventional concept of translational research, investigations flow from the laboratory bench to the bedside. However, clinical research can also serve as the starting point for subsequent laboratory investigations...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Comments on: Pharmacokinetics of cisplatin during open and minimally-invasive secondary cytoreductive surgery plus HIPEC in women with platinum-sensitive recurrent ovarian cancer: a prospective study

Batista TP, Kusamura S

No abstract available.
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Simultaneous quantification of ticagrelor and its active metabolite, AR-C124910XX, in human plasma by liquid chromatography-tandem mass spectrometry: Applications in steady-state pharmacokinetics in patients

Chae SU, Min KL, Lee CB, Huang Z, Chang MJ, Bae SK

A sensitive and simple liquid chromatography-tandem mass spectrometry method was developed and validated for the simultaneous quantification of ticagrelor and its active metabolite, AR-C124910XX from 50 µL human plasma using...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Pharmacokinetics of cisplatin during open and minimally-invasive secondary cytoreductive surgery plus HIPEC in women with platinum-sensitive recurrent ovarian cancer: a prospective study

Petrillo M, Zucchetti , Cianci S, Morosi L, Ronsini C, Colombo A, D'Incalci , Scambia G, Fagotti A

OBJECTIVE: Evidences from animal models seem to suggest that minimally invasive surgery may enhance cisplatin diffusion when the drug is administered in the context of post-operative hyperthermic intraperitoneal chemotherapy (HIPEC)....
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Understanding the pharmacokinetics of reversible metabolism

Cho S, Yoon YR

This tutorial introduces the mathematical skills required to obtain exact and approximate solutions for reversible reactions and provides graphical insights to help understand the pharmacokinetics of reversible metabolism. The matrix...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Effects of CYP1A enzyme specific inhibitor on pharmacokinetics of para-acetaminophen in Bactrian camel

San R, Yue W, Hasi S

The effects of CYP1A enzyme on the pharmacokinetics of p-acetaminophen were studied in Bactrian camel. Twelve Bactrian camels were divided into 2 groups, then given a single dose of p-acetaminophen...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Pharmacokinetics of enrofloxacin HCl-2Hâ‚‚O (Enro-C) in dogs and pharmacokinetic/pharmacodynamic Monte Carlo simulations against Leptospira spp.

Sumano H, Ocampo L, Tapia G, Mendoza CD, Gutierrez

Pharmacokinetic/pharmacodynamic (PK/PD) ratios of reference enrofloxacin (Enro-R) and enrofloxacin as HCl-2H₂O (Enro-C), as well as Monte Carlo simulations based on composite MIC₅₀ and MIC₉₀ (MIC, minimum inhibitory concentration) vs. Leptospira...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Effect of plasma membrane monoamine transporter genetic variants on pharmacokinetics of metformin in humans

Moon SJ, Oh J, Lee SH, Choi Y, Yu KS, Chung JY

Metformin, an oral hypoglycemic agent belonging to biguanide class, is widely used to treat type 2 diabetes mellitus, and several drug transporters such as organic cation transporters (OCTs), multidrug and...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Pharmacokinetics comparison of solifenacin tartrate and solifenacin succinate: a randomized, open-label, single-dose, 2-way crossover study in healthy male volunteers

Kim YM, Jeon JY, Moon SJ, Jung J, Son H, Kim MG

Solifenacin is a muscarinic antagonist indicated for the treatment of overactive bladder with symptoms. Solifenacin tartrate is a newly developed salt formulation of solifenacin. This study compared the pharmacokinetic and...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Pharmacokinetics of fixed-dose combination of rosuvastatin 20 mg and ezetimibe 10 mg compared to concurrent administration of individual tablets in healthy Korean subjects

Hwang I, Park SI, Lee S, Lee B, Yu KS, Jeon JY, Kim MG

This study aimed to compare the pharmacokinetics of fixed-dose combination (FDC) tablet of rosuvastatin 20 mg/ezetimibe 10 mg with that of concurrent administration of individual rosuvastatin 20 mg tablet and...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Understanding the pharmacokinetics of prodrug and metabolite

Cho S, Yoon YR

This tutorial explains the pharmacokinetics of a prodrug and its active metabolite (or parent drug) using a two-step, consecutive, first-order irreversible reaction as a basic model for prodrug metabolism. In...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Comparison of pharmacokinetics and safety of fixed-dose combination of SKI306X and aceclofenac versus separate tablets in healthy subjects

Meng X, Oh ES, Park MS, Kim D, Kim JH, Kim CO

JOINS (SKI306X) is an herbal anti-arthritic medicine that is widely used with aceclofenac for treating osteoarthritis in Korea. A fixed-dose combination (FDC) tablet containing SKI306X and aceclofenac was developed to...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Pharmacokinetics of atorvastatin and sustained-release metformin fixed-dose combination tablets: two randomized, open-label, 2-way crossover studies in healthy male subjects under fed conditions

Choi YK, Park SE, Kim EY, Park HJ, Kim EJ, Song GS, Ghim JL

Two separate studies were conducted to establish bioequivalence (BE) for two doses of atorvastatin/metformin sustained-release (SR) fixed dose combination (FDC) versus the same dosage of the individual component (IC) tablets...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Screening study for genetic polymorphisms affecting pharmacokinetics of talniflumate

Jin LH, Kim BH, Lee JH, Lee K, Kwack K, Yim SV

Talniflumate is a phthalidyl ester of niflumic acid, which has potent analgesic and anti-inflammatory effects and is widely used to treat inflammatory disorders, such as rheumatoid arthritis. To screen the...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Pharmacokinetics of tilmicosin in healthy pigs and in pigs experimentally infected with Haemophilus parasuis

Zhang L, Zhao L, Liu Y, Liu J, Li X

A comparative in vivo pharmacokinetic (PK) study of tilmicosin (TIL) was conducted in 6 crossbred healthy pigs and 6 crossbred pigs infected with Haemophilus (H.) parasuis following oral administration of...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Role of the ABCB1 Drug Transporter Polymorphisms in the Pharmacokinetics of Oseltamivir in Humans: a Preliminary Report

Cha YJ, Ghim JL

Oseltamivir is a substrate of P-glycoprotein, an efflux drug transporter encoded by ABCB1. The objective of this study was to assess the role of ABCB1 (c.1236C>T, c.2677G>T/A, and c.3435C>T) polymorphisms...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Pharmacokinetics and drug therapy in neonates

Cho HJ

Neonates include both full term and preterm infants up to 28 days of age. The heterogeneity and rapid physiologic change of neonates affect all aspects of pharmacokinetics such as absorption,...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Clinical Pharmacokinetics of Caffeine in Korean Preterm Infants with Apnea of Prematurity

Lim MS, Son MJ, Shin JE, Lee SM, Eun HS, Park MS, Park KI, Namgung R

PURPOSE: Caffeine shows wide interindividual pharmacokinetic (PK) variation, and therapeutic drug monitoring (TDM) may be needed. The PK profile of caffeine in Korean preterm neonates was investigated, and factors influencing...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Experience and pharmacokinetics of Levetiracetam in Korean neonates with neonatal seizures

Shin JW, Jung YS, Park K, Lee SM, Eun HS, Park MS, Park KI, Namgung R

PURPOSE: The aims of this study were to evaluate the safety and pharmacokinetics of levetiracetam (LEV) in neonates with seizures and to establish a population pharmacokinetics (PPK) model by using...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2023 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr