- Oxidative Stress in Vivax Malaria
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Bilgin R, Yalcin MS, Yucebilgic G, Koltas IS, Yazar S
- KMID: 1792135
- Korean J Parasitol.
- 2012 Dec;50(4):375-377.
Malaria is still a leading cause of morbidity and mortality. The increase in lipid peroxidation reported in malaria infection and antioxidant status may be a useful marker of oxidative stress... -
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- Antioxidant activity of extracts from Euryale ferox seed
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Lee SE, Ju EM, Kim JH
- KMID: 1081458
- Exp Mol Med.
- 2002 May;34(2):100-106.
Euryale ferox has been widely used in traditional oriental medicine to treat a variety of illness. However, very little is known about the cellular actions by which this plant mediates... -
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- Ischemic preconditioning in the rat hippocampus increases antioxidant activities but does not affect the level of hydroxyl radicals during subsequent severe ischemia
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Choi YS, Cho KO, Kim EJ, Sung KW, Kim SY
- KMID: 756079
- Exp Mol Med.
- 2007 Aug;39(4):556-563.
Several studies have demonstrated that ischemic preconditioning increases superoxide dismutase activity, but it is unclear how ischemic preconditioning affects events downstream of hydrogen peroxide production during subsequent severe ischemia and... -
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- Superoxide Anion Production by Human Neutrophils Activated by Trichomonas vaginalis
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Song HO, Ryu JS
- KMID: 1715697
- Korean J Parasitol.
- 2013 Aug;51(4):479-484.
- doi: 10.3347/kjp.2013.51.4.479
Neutrophils are the predominant inflammatory cells found in vaginal discharges of patients infected with Trichomonas vaginalis. In this study, we examined superoxide anion (O2(.-)) production by neutrophils activated by T.... -
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- Bisphenol A Impairs Mitochondrial Function in the Liver at Doses below the No Observed Adverse Effect Level
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Moon MK, Kim MJ, Jung IK, Koo YD, Ann HY, Lee KJ, Kim SH, Yoon YC, Cho BJ, Park KS, Jang HC, Park YJ
- KMID: 1421617
- J Korean Med Sci.
- 2012 Jun;27(6):644-652.
- doi: 10.3346/jkms.2012.27.6.644
Bisphenol A (BPA) has been reported to possess hepatic toxicity. We investigated the hypothesis that BPA, below the no observed adverse effect level (NOAEL), can induce hepatic damage and mitochondrial... -
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- Grape extracts suppress the formation of preneoplastic foci and activity of fatty acid synthase in rat liver
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Kweon S, Kim Y, Choi H
- KMID: 1093609
- Exp Mol Med.
- 2003 Oct;35(5):371-378.
This study was conducted to examine the effects of dietary grape extracts on preneoplastic foci formation in rat hepatocarcinogenesis, and related hepatic enzymes. Male Sprague-Dawley rats were fed basal diet... -
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- Phytotherapeutic effects of Echinacea purpurea in gamma-irradiated mice
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Abouelella AM, Shahein YE, Tawfik SS, Zahran AM
- KMID: 1106213
- J Vet Sci.
- 2007 Dec;8(4):341-351.
- doi: 10.4142/jvs.2007.8.4.341
Echinacea (E.) purpurea herb is commonly known as the purple coneflower, red sunflower and rudbeckia. In this paper, we report the curative efficacy of an Echinacea extract in gamma-irradiated mice.... -
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- Ethyl Pyruvate Has Anti-Inflammatory and Delayed Myocardial Protective Effects after Regional Ischemia/Reperfusion Injury
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Jang IS, Park MY, Shin IW, Sohn JT, Lee HK, Chung YK
- KMID: 1779628
- Yonsei Med J.
- 2010 Nov;51(6):838-844.
- doi: 10.3349/ymj.2010.51.6.838
PURPOSE: Ethyl pyruvate has anti-inflammatory properties and protects organs from ischemia/reperfusion (I/R)-induced tissue injury. The aim of this study was to determine whether ethyl pyruvate decreases the inflammatory response after... -
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- Ginsenoside Rb1 attenuates intestinal ischemia-reperfusion- induced liver injury by inhibiting NF-kappa B activation
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Wang J, Qiao L, Li Y, Yang G
- KMID: 1072949
- Exp Mol Med.
- 2008 Dec;40(6):686-698.
- doi: 10.3858/emm.2008.40.6.686
Intestinal ischemia-reperfusion (I/R) is an important event in the pathogenesis of multiple organ dysfunction syndrome (MODS). The aim of this study is to determine the effects of ginsenoside Rb1 on... -
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- Difficult Establishment of a Chronic Nonsteroidal Anti-inflammatory Drugs Induced Gastric Inflammation Rat Model due to Gastric Adaptation and Small Bowel Damage
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Lee BH, Kim N, Nam RH, Lee JY, Lee HS, Lee CH, Park JH, Lee DH
- KMID: 2234034
- Korean J Gastroenterol.
- 2014 Jun;63(6):341-347.
- doi: 10.4166/kjg.2014.63.6.341
BACKGROUND/AIMS: The prevalence of peptic ulcer disease has not decreased mainly due to an increase in the use of NSAIDs. This study was conducted in order to determine whether a... -
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- Açaà Berries Inhibit Colon Tumorigenesis in Azoxymethane/Dextran Sulfate Sodium-Treated Mice
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Choi YJ, Choi YJ, Kim N, Nam RH, Lee S, Lee HS, Lee HN, Surh YJ, Lee DH
- KMID: 2412191
- Gut Liver.
- 2017 Mar;11(2):243-252.
- doi: 10.5009/gnl16068
BACKGROUND/AIMS: The aim of this study was to investigate the protective effect of açaà against azoxymethane (AOM)/dextran sulfate sodium (DSS)-induced colorectal cancer development. METHODS: The effect of açaà on tumorigenesis was... -
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- Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) Augments Acute Lung Injury via Its Neutrophil Priming Effects
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Choi JC, Jung JW, Kwak HW, Song JH, Jeon EJ, Shin JW, Park IW, Choi BW, Kim JY
- KMID: 1713463
- J Korean Med Sci.
- 2008 Apr;23(2):288-295.
- doi: 10.3346/jkms.2008.23.2.288
Granulocyte macrophage-colony stimulating factor (GM-CSF) has immuno-stimulatory effects. We hypothesized that GM-CSF plays an important role both in lipopolysaccharide (LPS)- and hemorrhage-induced acute lung injury (ALI). We also postulated that... -
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- Discrepant Immunophenotypic Characteristics between the Lymph Node and Bone Marrow in Two Mixed-Phenotype Acute Leukemia Patients
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Song MJ, Kim HJ, Ko YH, Kim SH
- KMID: 1077414
- Korean J Lab Med.
- 2009 Oct;29(5):396-401.
- doi: 10.3343/kjlm.2009.29.5.396
The immunophenotypic profile of hematological malignancies is usually consistent among different sites of involvement; this consistency allows reliable diagnosis from peripheral blood, bone marrow, or lymph node, especially in cases... -
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- Alteration of nitrergic neuromuscular transmission as a result of acute experimental colitis in rat
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Sung TS, La JH, Kim TW, Yang IS
- KMID: 1059200
- J Vet Sci.
- 2006 Jun;7(2):143-150.
- doi: 10.4142/jvs.2006.7.2.143
Nitric oxide (NO) is a non-adrenergic, non-cholinergic neurotransmitter found in the enteric nervous system that plays a role in a variety of enteropathies, including inflammatory bowel disease. Alteration of nitrergic neurons has been reported... -
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- Down-regulation of survivin suppresses uro-plasminogen activator through transcription factor JunB
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Lee KH, Choi EY, Koh SA, Kim MK, Kim KO, Lee SH, Jang BI, Kim SW, Kim SW, Song SK, Choi JH, Kim JR
- KMID: 1022126
- Exp Mol Med.
- 2011 Sep;43(9):501-509.
- doi: 10.3858/emm.2011.43.9.057
Survivin, a member of the inhibitors of apoptosis protein family, is expressed during development and in various human cancers. However, the clinical relevance of survivin in cancer is still a... -
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- The Effect of High Dose Melatonin on Cardiac Ischemia-reperfusion Injury
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Ceyran H, Narin F, Narin N, Akgun H, Ceyran AB, Ozturk F, Akcali Y
- KMID: 2158191
- Yonsei Med J.
- 2008 Oct;49(5):735-741.
- doi: 10.3349/ymj.2008.49.5.735
PURPOSE: Melatonin, the most potent scavenger of toxic free radicals, has been found to be effective in protecting against pathological states due to the release of reactive oxygen species. This... -
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- Gastroprotective Effects of PMK-S005 against Ethanol-Induced Acute Gastric Damage in Rats
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Choi YJ, Kim N, Lee JY, Nam RH, Seo JH, Lee S, Kim HJ, Choi YJ, Lee HS, Lee DH
- KMID: 2411960
- Gut Liver.
- 2016 May;10(3):348-355.
- doi: 10.5009/gnl14509
BACKGROUND/AIMS: This study aimed to examine the gastroprotective effects of PMK-S005, which is a synthetic S-allyl-L-cysteine (SAC; a sulfur-containing amino acid), against acute ethanol-induced gastric damage in rats. METHODS: Sprague-Dawley rats... -
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- The functional role of the CARM1-SNF5 complex and its associated HMT activity in transcriptional activation by thyroid hormone receptor
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Choi HK, Choi KC, Oh SY, Kang HB, Lee YH, Haam S, Ahn YH, Kim KS, Kim K, Yoon HG
- KMID: 756078
- Exp Mol Med.
- 2007 Aug;39(4):544-555.
We have investigated the function and mechanisms of the CARM1-SNF5 complex in T3-dependent transcriptional activation. Using specific small interfering RNAs (siRNA) to knock down coactivators in HeLa alpha2 cells, we... -
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- Grifola frondosa water extract alleviates intestinal inflammation by suppressing TNF-alpha production and its signaling
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Lee JS, Park SY, Thapa D, Choi MK, Chung IM, Park YJ, Yong CS, Choi HG, Kim JA
- KMID: 983987
- Exp Mol Med.
- 2010 Feb;42(2):143-154.
- doi: 10.3858/emm.2010.42.2.016
TNF-alpha is a major cytokine involved in inflammatory bowel disease (IBD). In this study, water extract of Grifola frondosa (GFW) was evaluated for its protective effects against colon inflammation through... -
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- Granulocyte Colony Stimulating Factor Attenuates Hyperoxia-Induced Lung Injury by Down-Modulating Inflammatory Responses in Neonatal Rats
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Jeon GW, Sung DK, Jung YJ, Koo SH, Choi SH, Chang YS, Sin JB, Park WS
- KMID: 1106439
- Yonsei Med J.
- 2011 Jan;52(1):65-73.
- doi: 10.3349/ymj.2011.52.1.65
PURPOSE: Granulocyte colony stimulating factor (G-CSF) has been known to increase neutrophil production and have anti-inflammatory properties, but the effect of G-CSF on pulmonary system is in controversy. We investigated... -
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