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Duodenal Stricture due to Necrotizing Pancreatitis following Endoscopic Ultrasound-Guided Ethanol Ablation of a Pancreatic Cyst: A Case Report

Chun JW, Lee SH, Choi JH, Paik WH, Ryu JK, Kim YT

The frequency of incidental detection of pancreatic cystic lesions (PCLs) is increasing because of the frequent use of cross-sectional imaging. The appropriate treatment for PCLs is challenging, and endoscopic ultrasound-guided...
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Hypertriglyceridemia-induced Severe Necrotizing Pancreatitis Following Low Dose Tamoxifen Administration

Jang YH, Kim HJ

A 51-year-old woman visited the emergency room with severe abdominal pain of acute onset. She had undergone a breast cancer operation one year previously and had been taking a half-dose...
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Feasibility of Adopting the “Step-up Approach” in Managing Necrotizing Pancreatitis-induced Pancreatic-colonic Fistula

Yim SK, Kim SH, Seo SY, Yang HC, Lee SO

Managing acute pancreatitis is clinically challenging because of the generally poor patient condition, the variety of treatment options depending on the severity and complications, and the uncertainty of outcomes. Recently,...
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Severe necrotizing pancreatitis after endoscopic papillectomy in a patient with ampullary adenoma

Jang DK, Moon JY, Lee SH, Lee JK

SUMMARY OF EVENT: A 38-year-old man diagnosed with ampullary adenoma was referred for further treatment, and initially treated with the endoscopic papillectomy without complications. Recurred lesions were found during follow-up...
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Outcomes of Infected versus Symptomatic Sterile Walled-Off Pancreatic Necrosis Treated with a Minimally Invasive Therapy

Hyun JJ, Sahar N, Singla A, Ross AS, Irani SS, Gan SI, Larsen MC, Kozarek RA, Gluck M

BACKGROUND/AIMS: Acute pancreatitis complicated by walled-off necrosis (WON) is associated with high morbidity and mortality, and if infected, typically necessitates intervention. Clinical outcomes of infected WON have been described as...
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Optimal Therapeutic Options for Complex Walled-Off Necrosis: Endoscopic and Percutaneous Drainage

So H, Jo S, Song TJ

Up to 15% of acute pancreatitis can develop to acute necrotizing pancreatitis characterized by necrosis of the pancreas parenchyma and/or the peripancreatic tissue. It is associated with high rates of...
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Intramural Gastric Hematoma after Acute Necrotizing Pancreatitis: A Case Report and Review of Imaging Findings

Lee J, Park SH, Choi SJ, Ahn SJ, Kim HS, Shim Y, Kim YS

Intramural hematoma of the gastrointestinal tract is a rare disease entity. Pancreatitis-induced intramural gastric hematoma (IGH) is far more seldom reported. Here, we report a rare case of a giant...
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Pancreatic Necrosectomy through Sinus Tract Endoscopy

Goenka MK, Goenka U, Mujoo M, Tiwary IK, Mahawar S, Rai VK

BACKGROUND/AIMS: Direct endoscopic pancreatic necrosectomy is increasingly being utilized to treat infected or symptomatic walled-off necrosis (WON) located close to the stomach or duodenum. Laterally-placed WON has traditionally been treated...
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Necrotizing Pancreatitis: Current Management and Therapies

Boumitri C, Brown E, Kahaleh M

Acute necrotizing pancreatitis accounts for 10% of acute pancreatitis (AP) cases and is associated with a higher mortality and morbidity. Necrosis within the first 4 weeks of disease onset is...
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Acute Necrotizing Pancreatitis Caused by Iatrogenic Hypercalcemia

Oh EH, Song TJ, Nam K, Park DH, Lee SS, Seo DW, Lee SK, Kim MH

Gallstones and alcohol consumption are well-known causes of acute pancreatitis, which usually follows a mild and self-limited course. Although extremely rare, hypercalcemia is a possible cause of acute pancreatitis. There...
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Acute Emphysematous Pancreatitis with Fulminant Multi-organ Failure

Hong SW, Kang J, Youk J, Hwang JH, Kim J

An emphysematous pancreatitis is a rare, but fatal subtype of acute pancreatitis. Gas-forming bacteria from the bowel may penetrate the pancreas to cause emphysematous pancreatitis. It is characterized by the...
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Acute Pancreatitis and Gastroduodenal Intussusception Induced by an Underlying Gastric Gastrointestinal Stromal Tumor: A Case Report

Yildiz MS, DoÄŸan A, Koparan IH, Adin ME

Gastrointestinal stromal tumors (GISTs) are rare tumors of the gastrointestinal system and comprise only 1% to 3% of all gastrointestinal tract tumors, with the majority of them arising in the...
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Multiple Ascending Aortic Mural Thrombi and Acute Necrotizing Mediastinitis Secondary to Acute Pancreatitis

Chong BK, Yun JK, Kim JB, Park DH

The formation of aortic thrombi is an extremely rare complication of acute pancreatitis. Here we report a case of acute pancreatitis complicated by a paraesophageal pseudocyst, necrotizing mediastinitis, and the...
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Wernicke Encephalopathy after Endoscopic Necrosectomy in Acute Necrotizing Pancreatitis with WOPN: A Case Report

Kim M, Kang EK, Kim SY, Kim JY, Moon SM, Seo YH, Cho JH, Park YS

Infected walled-off pancreatic necrosis (WOPN) is dangerous complication of acute pancreatitis. Open necrosectomy and post-operative irrigation of necrotic cavity have been conventional treatment for infected pancreatic necrosis, however, recently minimally...
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Acute Necrotizing Pancreatitis Associated with Mycoplasma pneumoniae Infection in a Child

Yang A, Kang B, Choi SY, Cho JB, Kim YJ, Jeon TY, Choe YH

Mycoplasma pneumoniae is responsible for approximately 20% to 30% of community-acquired pneumonia, and is well known for its diverse extrapulmonary manifestations. However, acute necrotizing pancreatits is an extremely rare extrapulmonary...
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Pyrrolidine Dithiocarbamate Inhibits Nuclear Factor kappaB and Toll-Like Receptor 4 Expression in Rats with Acute Necrotizing Pancreatitis

Xu M, Wang KN, Wu K, Wang XP

BACKGROUND/AIMS: To investigate the expression of Toll-like receptor 4 (TLR4) in the pancreases of rats with acute necrotizing pancreatitis (ANP) and any changes upon treatment with pyrrolidine dithiocarbamate (PDTC), an...
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Acute Necrotizing Pancreatitis during L-asparaginase Treatment in a Patient with Acute Lymphoblastic Leukemia

Lee JA, Kim HJ, Kim JS, Lee JM, Kim JE, Lim SY, Kim SM, Lee YH

L-asparaginase is an important component of antileukemic therapy in patients with acute lymphoblastic leukemia. The degree of L-asparaginase toxicity is variable. Several cases of L-asparaginase related pancreatitis have been reported...
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Balloon Occlusion Retrograde Transvenous Obliteration of Gastric Varices in Two Non-Cirrhotic Patients with Portal Vein Thrombosis

Borghei P, Kim SK, Zuckerman

This report describes two non-cirrhotic patients with portal vein thrombosis who underwent successful balloon occlusion retrograde transvenous obliteration (BRTO) of gastric varices with a satisfactory response and no complications. One...
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A Case of Colonic Perforation after Acute Necrotizing Pancreatitis

Song YJ, Choi JS, Park SY, Park YJ, An MS, Bae KB, Hong KH

Colonic perforation after acute necrotizing pancreatitis is a very rare but critical complication. The mortality rate is greater than 50%. Therefore, a high index of suspicion is needed for early...
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N-Acetylcysteine Improves Pancreatic Microcirculation and Alleviates the Severity of Acute Necrotizing Pancreatitis

Du BQ, Yang YM, Chen YH, Liu XB, Mai G

BACKGROUND/AIMS: To investigate the beneficial effect of N-Acetylcysteine (NAC) on pancreatic microvascular perfusion in acute necrotizing pancreatitis (ANP). METHODS: Fifty-four rats were divided into a control group, an ANP group and...
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