- Peroxisome Proliferator-Activated Receptor-Gamma Expression in the Lung Tissue of Obese Rats
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Hwang SJ, Kim JH, Shim JW, Kim DS, Jung HL, Park MS, Lee WY, Kim SY, Shim JY
- KMID: 1777023
- Yonsei Med J.
- 2011 May;52(3):495-501.
- doi: 10.3349/ymj.2011.52.3.495
PURPOSE: Obesity is a risk factor for asthma and type II diabetes. Peroxisome proliferator-activated receptor (PPAR)-gamma has been suggested to regulate inflammatory responses in diabetes and asthma. We investigated whether... -
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- Saccharomyces boulardii Activates Expression of Peroxisome Proliferator-activated Receptor-gamma in HT-29 Cells
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Lee SK, Kim HJ, Chi SG, Jang JY, Nam KD, Kim NH, Joo KR, Dong SH, Kim BH, Chang YW, Lee JI, Chang R
- KMID: 772773
- Korean J Gastroenterol.
- 2005 May;45(5):328-334.
BACKGROUND/AIMS: Saccharomyces boulardii (S. boulardii) has been reported to be beneficial in the treatment of inflammatory bowel disease, however, little is known about its mechanism of action. Peroxisome proliferator-... -
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- Preclinical Study of Cell Therapy for Osteonecrosis of the Femoral Head with Allogenic Peripheral Blood-Derived Mesenchymal Stem Cells
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Fu Q, Tang NN, Zhang Q, Liu Y, Peng JC, Fang N, Yu LM, Liu JW, Zhang T
- KMID: 2374136
- Yonsei Med J.
- 2016 Jul;57(4):1006-1015.
- doi: 10.3349/ymj.2016.57.4.1006
PURPOSE: To explore the value of transplanting peripheral blood-derived mesenchymal stem cells from allogenic rabbits (rPBMSCs) to treat osteonecrosis of the femoral head (ONFH). MATERIALS AND METHODS: rPBMSCs were separated/cultured from... -
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- DNA Methylation Patterns of Ulcer-Healing Genes Associated with the Normal Gastric Mucosa of Gastric Cancers
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Hong SJ, Oh JH, Jung YC, Kim YH, Kim SJ, Kang SJ, Seo EJ, Choi SW, Kang MI, Rhyu MG
- KMID: 1778036
- J Korean Med Sci.
- 2010 Mar;25(3):405-417.
- doi: 10.3346/jkms.2010.25.3.405
Recent evidence suggests that gastric mucosal injury induces adaptive changes in DNA methylation. In this study, the methylation status of the key tissue-specific genes in normal gastric mucosa of healthy... -
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- Modulation of the Transcriptional Activity of Peroxisome Proliferator-Activated Receptor Gamma by Protein-Protein Interactions and Post-Translational Modifications
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Kim TH, Kim MY, Jo SH, Park JM, Ahn YH
- KMID: 1727863
- Yonsei Med J.
- 2013 May;54(3):545-559.
- doi: 10.3349/ymj.2013.54.3.545
Peroxisome proliferator-activated receptor gamma (PPARgamma) belongs to a nuclear receptor superfamily; members of which play key roles in the control of body metabolism principally by acting on adipose tissue. Ligands... -
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- The Effect of Chlamydia pneumoniae on the Expression of Peroxisome Proliferator-Activated Receptor-gamma in Vascular Smooth Muscle Cells
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Kim YH, Choi SY, Suh JH, Kim TK, Seung KB, Wang YP, Chang K
- KMID: 1084495
- Yonsei Med J.
- 2008 Apr;49(2):230-236.
- doi: 10.3349/ymj.2008.49.2.230
PURPOSE: This study was designed to investigate the change of peroxisome proliferator-activated receptor gamma (PPARgamma) after the infection of the human coronary artery smooth muscle cells (HCSMCs) with Chlamydia pneumoniae... -
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- Down-regulation of ATP-binding cassette transporter G1 expression by unmethylated CpG oligodeoxynucleotides in RAW 264.7 macrophages
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Seo JM, Lee JY, Ji GE, You JC
- KMID: 1022127
- Exp Mol Med.
- 2011 Sep;43(9):510-516.
- doi: 10.3858/emm.2011.43.9.058
We have investigated the effect of various forms of phosphodiester cytidine-phosphate-guanosine oligodeoxynucleotides (CpG ODNs) on the production of pro-inflammatory cytokines and related genes in RAW 264.7 macrophages. Treatment with the... -
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- Emodin ameliorates high-glucose induced mesangial p38 over-activation and hypocontractility via activation of PPARgamma
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Liu Y, Jia L, Liu ZC, Zhang H, Zhang PJ, Wan Q, Wang R
- KMID: 756208
- Exp Mol Med.
- 2009 Sep;41(9):648-655.
- doi: 10.3858/emm.2009.41.9.071
Early stage diabetic nephropathy is characterized by elevated glomerular filtration. Recent studies have identified high-glucose induced p38 MAPK (p38) over-activation in mesangial cells. Mesangial hypocontractility is the major underlying mechanism,... -
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