- Oxidative Stress Modulates the Expression Pattern of Peroxiredoxin-6 in Peripheral Blood Mononuclear Cells of Asthmatic Patients and Bronchial Epithelial Cells
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Shim HJ, Park SY, Kwon HS, Song WJ, Kim TB, Moon KA, Choi JP, Kim SJ, Cho YS
- KMID: 2471234
- Allergy Asthma Immunol Res.
- 2020 May;12(3):523-536.
- doi: 10.4168/aair.2020.12.3.523
PURPOSE: Reduction-oxidation reaction homeostasis is vital for regulating inflammatory conditions and its dysregulation may affect the pathogenesis of chronic airway inflammatory diseases such as asthma. Peroxiredoxin-6, an important intracellular anti-oxidant... -
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- Effects of Particulate Respirator Use on Cardiopulmonary Function in Elderly Women: a Quasi-Experimental Study
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Lim YH, Kim W, Choi Y, Kim HC, Na G, Kim HR, Hong YC
- KMID: 2471798
- J Korean Med Sci.
- 2020 Mar;35(10):e64.
- doi: 10.3346/jkms.2020.35.e64
BACKGROUND: Individual particulate respirator use may offer protection against exposure to particulate matter < 2.5 µm in diameter (PM(2.5)). Among elderly Korean women, we explored individual particulate respirator use and... -
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- Mitochondrial Mechanisms in Diabetic Cardiomyopathy
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Gollmer J, Zirlik A, Bugger H
- KMID: 2470953
- Diabetes Metab J.
- 2020 Feb;44(1):33-53.
- doi: 10.4093/dmj.2019.0185
Mitochondrial medicine is increasingly discussed as a promising therapeutic approach, given that mitochondrial defects are thought to contribute to many prevalent diseases and their complications. In individuals with diabetes mellitus... -
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- Neuroprotective effects of urolithin A on Hâ‚‚Oâ‚‚-induced oxidative stress-mediated apoptosis in SK-N-MC cells
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Kim KB, Lee S, Kim JH
- KMID: 2468507
- Nutr Res Pract.
- 2020 Feb;14(1):3-11.
- doi: 10.4162/nrp.2020.14.1.3
BACKGROUND/OBJECTIVES: Oxidative stress causes cell damage and death, which contribute to the pathogenesis of neurodegenerative diseases. Urolithin A (UA), a gut microbial-derived metabolite of ellagitannins and ellagic acid, has high... -
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- A Comparative Study of the Effect of Flaxseed Oil and Sunflower Oil on the Coagulation Score, Selected Oxidative and Inflammatory Parameters in Metabolic Syndrome Patients
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Akrami A, Makiabadi , Askarpour , Zamani K, Hadi A, Mokari-Yamchi A, Babajafari S, Faghih S, Hojhabrimanesh A
- KMID: 2468665
- Clin Nutr Res.
- 2020 Jan;9(1):63-72.
- doi: 10.7762/cnr.2020.9.1.63
Metabolic syndrome (MetS) is a chronic disease with inflammatory and hypercoagulable states. The current study aimed to compare the effects of flaxseed oil and sunflower oil consumption on the coagulation... -
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- Effects of Quercetin Supplementation on Hematological Parameters in Non-Alcoholic Fatty Liver Disease: a Randomized, Double-Blind, Placebo-Controlled Pilot Study
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Pasdar Y, Oubari F, Zarif MN, Abbasi M, Pourmahmoudi A, Hosseinikia M
- KMID: 2468660
- Clin Nutr Res.
- 2020 Jan;9(1):11-19.
- doi: 10.7762/cnr.2020.9.1.11
Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease which has become a public health concern. Since oxidative stress plays a crucial role in the pathogenesis of NAFLD,... -
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- Spatiotemporal expression of RCAN1 and its isoform RCAN1-4 in the mouse hippocampus after pilocarpine-induced status epilepticus
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Cho KO, Jeong KH, Cha JH, Kim SY
- KMID: 2466572
- Korean J Physiol Pharmacol.
- 2020 Jan;24(1):81-88.
- doi: 10.4196/kjpp.2020.24.1.81
Regulator of calcineurin 1 (RCAN1) can be induced by an intracellular calcium increase and oxidative stress, which are characteristic features of temporal lobe epilepsy. Thus, we investigated the spatiotemporal expression... -
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- Proteomic Signatures in Spermatozoa Reveal the Role of Paternal Factors in Recurrent Pregnancy Loss
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Mohanty G, Jena SR, Nayak J, Kar S, Samanta L
- KMID: 2465415
- World J Mens Health.
- 2020 Jan;38(1):103-114.
- doi: 10.5534/wjmh.190034
PURPOSE: To identify the paternal factors responsible for aberrant embryo development leading to loss of foetus in recurrent pregnancy loss (RPL) through proteomic analysis of ejaculated spermatozoa. MATERIALS AND METHODS: This... -
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- Ritalinic Acid Stimulates Human Sperm Motility and Maintains Vitality In Vitro
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Harlev A, Henkel R, Samanta L, Agarwal A
- KMID: 2465410
- World J Mens Health.
- 2020 Jan;38(1):61-67.
- doi: 10.5534/wjmh.180127
PURPOSE: To evaluate the in vitro impact of ritalinic acid (RA), a major metabolite of methylphenidate (drug to treat attention-deficit hyperactivity disorder), on sperm motility, vitality and oxidative stress. MATERIALS AND... -
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- The Protective Effect of Green Tea Extract on Alpha-amanitin Induced Hepatotoxicity
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An SH, Sun KH, Hong R, Lee BR, Park Y
- KMID: 2470188
- J Korean Soc Clin Toxicol.
- 2019 Dec;17(2):58-65.
- doi: 10.22537/jksct.2019.17.2.58
PURPOSE: Alpha-amanitin induces potent oxidative stress and apoptosis, and may play a significant role in the pathogenesis of hepatotoxicity. This study examined the mechanisms of α-amanitin-induced apoptosis in vitro, and... -
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- The role of oxidative stress and hypoxia in renal disease
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Honda T, Hirakawa Y, Nangaku M
- KMID: 2469372
- Kidney Res Clin Pract.
- 2019 Dec;38(4):414-426.
- doi: 10.23876/j.krcp.19.063
Oxygen is required to sustain aerobic organisms. Reactive oxygen species (ROS) are constantly released during mitochondrial oxygen consumption for energy production. Any imbalance between ROS production and its scavenger system... -
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- Anti-Helicobacter pylori, Anti-apoptotic, and Cytoprotective Effects of Threonine Synthesized from Corynebacterium glutamicum in Gastric Epithelial Cells
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An JM, Kim YS, Hong YG, Hah BS, Sohn MS, Hahm KB
- KMID: 2469316
- Korean J Helicobacter Up Gastrointest Res.
- 2019 Dec;19(4):245-256.
- doi: 10.7704/kjhugr.2019.0011
BACKGROUND/AIMS: Among irritants causing gastric ulcer, Helicobacter pylori (H. pylori) might be pivotal, after which eradication became essential way in either inhibiting ulcerogenesis or preventing ulcer recurrence. Since threonine is... -
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- Autophagy, Cellular Aging and Age-related Human Diseases
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Cheon SY, Kim H, Rubinsztein DC, Lee JE
- KMID: 2468882
- Exp Neurobiol.
- 2019 Dec;28(6):643-657.
- doi: 10.5607/en.2019.28.6.643
Macroautophagy/autophagy is a conserved degradation system that engulfs intracytoplasmic contents, including aggregated proteins and organelles, which is crucial for cellular homeostasis. During aging, cellular factors suggested as the cause of... -
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- Two New Caffeoyl Threonate Esters from the Leaves of Toxicodendron vernicifluum
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Jang JY, Ahn JH, Jo YH, Turk A, Kang SY, Hwang BY, Lee MK
- KMID: 2468070
- Nat Prod Sci.
- 2019 Dec;25(4):354-357.
- doi: 10.20307/nps.2019.25.4.354
Toxicodendron vernicifluum, also called as Rhus verniciflua is a deciduous tree belonging to Anacardiaceae family. Two new caffeoyl threonate esters, rhuseols A (1) and B (2), together with 5-O-(E)-caffeoylquinic acid... -
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- Regulatory Pathway of Ion-Transporter Genes through Nrf2 Transcription Factor in Hypokalemic Condition
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Cho HJ, Ahn KY
- KMID: 2467467
- Anat Biol Anthropol.
- 2019 Dec;32(4):141-149.
- doi: 10.11637/aba.2019.32.4.141
The Nuclear factor-erythroid-2-related factor 2 (Nrf2) plays a key role in the cellular defense against oxidative stress. Low K+ increased the reactive oxygen species and it stimulate Nrf2 activation. Previous... -
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- Extraneural CGRP Induces Oxidative Stress in Kidney Proximal Tubule Epithelial Cells
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Moon D, Yoon SP, Jang HS, Noh MR, Ha L, Padanilam , Kim J
- KMID: 2467465
- Anat Biol Anthropol.
- 2019 Dec;32(4):121-128.
- doi: 10.11637/aba.2019.32.4.121
Calcitonin gene-related peptide (CGRP) is the most abundant neuropeptide in primary afferent sensory neurons. Exogenous CGRP can induce cell death in kidney tubular cells. The objective of this study was... -
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- Cancer Conditioned Medium Modulates Functional and Phenotypic Properties of Human Decidua Parietalis Mesenchymal Stem/Stromal Cells
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Bahattab E, Khatlani T, Abomaray F, Messaoudi , Abumaree M
- KMID: 2467054
- Tissue Eng Regen Med.
- 2019 Dec;16(6):615-630.
- doi: 10.1007/s13770-019-00207-w
BACKGROUND: Mesenchymal Stem/Stromal Cells (MSCs) from the decidua parietalis (DPMSCs) of human term placenta express several molecules with important biological and immunological properties. DPMSCs induce natural killer cell expression of... -
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- Antioxidant and antiobesity activities of oral treatment with ethanol extract from sprout of evening primrose (Oenothera laciniata) in high fat diet-induced obese mice
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Kwak CS, Kim MJ, Kim SG, Park S, Kim IG, Kang HS
- KMID: 2466667
- J Nutr Health.
- 2019 Dec;52(6):529-539.
- doi: 10.4163/jnh.2019.52.6.529
PURPOSE: Sprouts of evening primrose (Oenothera laciniata, OL) were reported to have high contents of flavonoids and potent antioxidant activity. This study examined the antioxidant and antiobesity activities of OL... -
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- Three Months Monitored Metabolic Fitness Modulates Cardiovascular Risk Factors in Diabetic Patients
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Cirilli I, Silvestri , Marcheggiani F, Olivieri F, Galeazzi R, Antonicelli R, Recchioni , Marcheselli F, Bacchetti , Tiano L, Orlando P
- KMID: 2466509
- Diabetes Metab J.
- 2019 Dec;43(6):893-897.
- doi: 10.4093/dmj.2018.0254
Cardiovascular diseases represent the leading cause of death and moderate physical exercise is associated with a reduction in cardiovascular risk. The aim of the study was to evaluate the correlation... -
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- Metformin Ameliorates Lipotoxic β-Cell Dysfunction through a Concentration-Dependent Dual Mechanism of Action
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Kim HI, Lee JS, Kwak BK, Hwang WM, Kim MJ, Kim YB, Chung SS, Park KS
- KMID: 2466506
- Diabetes Metab J.
- 2019 Dec;43(6):854-866.
- doi: 10.4093/dmj.2018.0179
BACKGROUND: Chronic exposure to elevated levels of free fatty acids contributes to pancreatic β-cell dysfunction. Although it is well known that metformin induces cellular energy depletion and a concomitant activation... -
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