J Korean Epilepsy Soc.  2004 Dec;8(2):103-107.

Epilepsy and Oxidative Stress

Affiliations
  • 1Department of Pediatrics, Chungbuk National University College of Medicine, Cheongju, Korea. wskim@chungbuk.ac.kr

Abstract

Epilepsy is arising from many molecular and biochemical events. In the underlying mechanisms of epilepsy, oxidative stress plays an important role in seizure-induced brain damage and neuronal death. Also epileptic seizures are noted in mitochondrial diseases with problems in oxidative phosphorylation. So oxidative stress is an important emerging cause of seizure-induced neuronal death as well as a result of epileptic seizure event.

Keyword

Epilepsy; Oxidative stress; Neuronal death; Mitochondri

MeSH Terms

Brain
Epilepsy*
Mitochondrial Diseases
Neurons
Oxidative Phosphorylation
Oxidative Stress*
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