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Severe Chronic Active EBV Infection in an Adult Patient: Case Report

Ha SY, Chung CW, Ko YH

Severe chronic active Epstein-Barr virus (EBV) infection is a rare and life-threatening illness. Although the criteria for diagnosis include chronic or recurrent infectious mononucleosis-like symptoms lasting more than 6 months...
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Effects of Propofol on Endotoxin-Induced Acute Lung Injury in Rabbit

Kwak SH, Choi JI, Park JT

This study was undertaken to clarify the effects of propofol on endotoxin-induced acute lung injury. Rabbits were randomly assigned to one of four groups. Each group received intravenous infusion of...
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Grape extracts suppress the formation of preneoplastic foci and activity of fatty acid synthase in rat liver

Kweon S, Kim Y, Choi H

  • KMID: 1093609
  • Exp Mol Med.
  • 2003 Oct;35(5):371-378.
This study was conducted to examine the effects of dietary grape extracts on preneoplastic foci formation in rat hepatocarcinogenesis, and related hepatic enzymes. Male Sprague-Dawley rats were fed basal diet...
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Fenofibrate regulates obesity and lipid metabolism with sexual dimorphism

Yoon MC, Jeong SH, Nicol CJ, Lee HH, Han MY, Kim JJ, Seo YJ, Ryu CY, Oh GT

  • KMID: 1121103
  • Exp Mol Med.
  • 2002 Dec;34(6):481-488.
To determine whether the PPARalpha agonist fenofibrate regulates obesity and lipid metabolism with sexual dimorphism, we examined the effects of fenofibrate on body weight, white adipose tissue (WAT) mass,...
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Aspartate modulates the ethanol-induced oxidative stress and glutathione utilizing enzymes in rat testes.

Oh SI, Lee MS, Kim CI, Song KY, Park SC

  • KMID: 1093597
  • Exp Mol Med.
  • 2002 Mar;34(1):47-52.
In order to develop a preventive strategy against ethanol-induced oxidative damages on various tissues and organs, we have examined the protective effect of aspartate on the pathogenesis of testes in...
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Development of Rat Prostatitis Model by Oral Administration of Isoflavone and Its Characteristics

Kwon SM, Kim SI, Chun DC, Cho NH, Chung BC, Park BW, Hong SJ

Inflammation of the prostate can be induced experimentally in rats by the subcutaneous administration of estrogen. However, it is usually achieved at the price of some alteration in the sex...
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Relationship between normal heart size and body indices in Korean

Seo JS, Lee SY, Won KJ, Kim DJ, Sohn DS, Yang KM, Cho SH, Park JD, Lee KH, Kim HD

We provided a curve-fit equation to predict the normal heart weight (g) in Koreans by examining 422 autopsies (215 males and 207 females, from newborn to age 77 yr) who...
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Dehydroepiandrosterone-dependent induction of peroxisomal proliferation can be reduced by aspartyl esterification without attenuation of inhibitory bone loss in ovariectomy animal model

Kwak CS, Kang CM, Kang HS, Song KY, Lee MS, Seong SC, Park SC

The purpose of this study was to determine whether esterification of dehydroepiandrosterone with aspartate (DHEA-aspartate) could reduce peroxisomal proliferation induced by DHEA itself, without loss of antiosteoporotic activity. Female Sprague-Dawley...
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Early ultrastructural changes of apoptosis induced by fumonisin B1 in rat liver

Moon WS, Kim JH, Kang MJ, Lee DG

A time sequential study was performed to investigate the histological and ultrastructural findings of fumonisin B1-induced apoptosis in the male Sprague-Dawley rat liver. Six hours after administration of FB1, marked...
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Augmented expression of cardiac atrial natriuretic peptide system in hypertensive rats

An MR, Chung YJ, Kang DG, Nam SC, Lee JU

The present study was aimed at investigating the regulation of atrial natriuretic peptide (ANP) system in association with either enhanced or attenuated activity of the renin-angiotensin system (RAS). The cardiac...
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Correlation of changes in natural killer cell activity and glutathione S-transferase placental form positive hepatocytes in diethylnitrosamine-induced rat hepatocarcinogenesis

Lee YS, Choe GY, Kim YI, Park SH, Park IA, Lee MJ, Jang JJ

To evaluate the induction of preneoplastic hepatic foci in relation to natural killer cell (NK) activity, we sequentially analyzed glutathione S-transferase placental form positive (GST-P+) hepatocytes and NK activity during ...
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Effect of cholestyramine on the formation of pigment gallstone in high carbohydrate diet-fed hamsters

Lee YC, Song DK, Kim JS, Choi CS

This study was designed to investigate the effect of cholestyramine on the formation of pigment gallstones in high carbohydrate diet-fed hamsters and whether that effect occurred because of cholecystokinin action....
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Development of altered hepatocyte foci by separate and combined treatments with radiation and diethylnitrosamine in neonatal rats

Kim SH, Lee YS, Lee MS, Kim TH, Jang JJ

To establish an in vivo radiation carcinogenesis model using glutathione S-transferase placental form positive (GST-P+) hepatic foci, newborn rats were irradiated once by 0.5 Gy and 2 Gy of gamma...
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Splenic lymphoid change in abdominal neoplasmic patients: analysis of 121 cases

Cho HJ, Ko IH

Because the spleen is likely to play a specific role in immunity, we have tried to observe the influence of the abdominal neoplasms on splenic lymphoid tissue as well as...
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Clinical Studies on Biometrics of the Placenta

Chung SO, Park KH

With increasing concern for the study of the fetal aspects of pregnancy and child-birth the availability of normal standards becomes more and more important. It is very difficult to test...
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Effect of Cold and Hot Environments on the Exocrine Pancreas of Rats

Kim YS, Kim WJ, Kim HK, Hong SS

Male albino rats fed 8 or 25% casein as a source of protein (designated here as low and high protein diet) were exposed to cold(4-5 degrees C) or heat (36-38...
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Effect of Long-Term Administration of Secretory Suppressives on Rat Pancreas (1)

Lee YS, Lee YB, Hong SS

Atropine (2.5 mg/kg), hexamethonium (1 mg/kg), Trasylol (1,000 u/kg), acetazolamide (100 mg/kg), cortisone (5 mg /kg) or procaine (5 mg/kg) were injected intraperitoneally once a day for 21 days into...
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Influence of Corticosteroids on the Hepatic Cell and Bile Secretion (1)

Kim YH, Lee YB, Hong SS

Daily administration of glucocorticoids for 10 days to dogs resulted in a significant increase in the hepatic bile secretion in response to secretory stimulants. The response of hepatic bile in...
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