- Comparison of oligonucleotide-microarray and serial analysis of gene expression (SAGE) in transcript profiling analysis of megakaryocytes derived from CD34+ cells
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Kim HL
- KMID: 1093620
- Exp Mol Med.
- 2003 Oct;35(5):460-466.
For the comprehensive analysis of transcript expression, the array-based hybridization analysis and the serial analysis of gene expression (SAGE) are commonly used platforms. The SAGE is based on a high-throughput... -
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- Microarray Analysis of Papillary Thyroid Cancers in Korean
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Kim HS, Kim DH, Kim JY, Jeoung NH, Lee IK, Bong JG, Jung ED
- KMID: 964721
- Korean J Intern Med.
- 2010 Dec;25(4):399-407.
- doi: 10.3904/kjim.2010.25.4.399
BACKGROUND/AIMS: Papillary thyroid cancer (PTC) is the most common malignancy of the thyroid gland. It involves several molecular mechanisms. The BRAF V600E mutation has been identified as the most common... -
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- Application of DNA chip techniques for Yq microdeletion analysis in infertile males
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Lee S, Joo HS, Lee SH, Park JE, Kim JM, Hwang JH, Cho KS, Hwang SY
- KMID: 1380213
- Exp Mol Med.
- 2004 Apr;36(2):179-184.
Our aim was to apply DNA chip technology as a diagnostic tool in infertility research and clinics. Six loci, including a sex-determining region on the Y chromosome and five sequence-tagged... -
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- A novel method using edge detection for signal extraction from cDNA microarray image analysis
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Kim JH, Kim HY, Lee YS
- KMID: 1085744
- Exp Mol Med.
- 2001 Jun;33(2):83-88.
Gene expression analyses by probes of hybridization from mRNA to cDNA targets arrayed on membranes or activated glass surfaces have revolutionized the way of profiling mega level gene expression. The... -
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- CpG Array Analysis of Histone H3 Lysine 4 Trimethylation by Chromatin Immunoprecipitation Linked to Microarrays Analysis in Peripheral Blood Mononuclear Cells of IgA Nephropathy Patients
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Qi S, Sui W, Yang M, Chen J, Dai Y
- KMID: 1120206
- Yonsei Med J.
- 2012 Mar;53(2):377-385.
- doi: 10.3349/ymj.2012.53.2.377
PURPOSE: The purpose of the present study was to investigate the aberrance of histone H3 lysine 4 trimethylation (H3K4me3) in patients with IgA Nephropathy (IgAN). MATERIALS AND METHODS: In this study,... -
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- Effect of local background intensities in the normalization of cDNA microarray data with a skewed expression profiles.
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KIm JH, Shin DM, Lee YS
- KMID: 1380230
- Exp Mol Med.
- 2002 Jul;34(3):224-232.
Normalization of the data of cDNA microarray is an obligatory step during microarray experiments due to the relatively frequent non-specific errors. Generally, normalization of microarray data is based on the... -
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- Microarray for Genes Associated with Signal Transduction in Diabetic OLETF Keratocytes
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Lee JE, Lee JS, Hwang SH
- KMID: 1101914
- Korean J Ophthalmol.
- 2007 Jun;21(2):111-119.
- doi: 10.3341/kjo.2007.21.2.111
PURPOSE: The purpose of this study was to identify differences in signal transduction gene expression between normal and diabetic keratocytes stimulated with interleukin-1alpha (IL-1alpha) and tumor necrosis factor-alpha (TNF-alpha). ... -
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