- The Study on the Effect of Nicorandil in Angina Pectoris
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Chung HC, Kim DM, Moon KS, Lee KS, Kim JS
- KMID: 2145754
- Korean Circ J.
- 1986 Mar;16(1):113-119.
- doi: 10.4070/kcj.1986.16.1.113
Clinical studies were performed that the patient with angina pectoris having no responses to Ca++ antagonist and beta-blocker had been taken nicorandil 5mg bid daily with, beta-blokade and Ca++ antagonists... -
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- Therapeutic Effect of Nicorandil on Angina Pectoris
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Kang JC, Park SJ, Kim SG, Jeong MH, Park JC, Park OK
- KMID: 2229685
- Korean Circ J.
- 1987 Jun;17(2):357-365.
- doi: 10.4070/kcj.1987.17.2.357
The antianginal effect of oral nicorandil was examined on 15 subjects with angina pectoris who had not been improved by previous treatment with beta blocker and/or calcium antagonists. Nicorandil, 5mg... -
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- Clinical Effects of Nicorandil on Angina Pectoris
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Choi YS, Kim CH, Kim YH, Oh BH, Park YB, Seo JD, Lee YW
- KMID: 1668919
- Korean Circ J.
- 1987 Dec;17(4):783-788.
- doi: 10.4070/kcj.1987.17.4.783
The effects of oral nicorandil were evaluated in 32 patients with angina pectoris who were diagnosed by typical chest pain and postitive treadmill exercise test from December 1986 throught May... -
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- Clinical Observation on Effect of Nicorandil in Angina Pectoris
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Lee KH, Chung WT, Park JG, Sohn GI, Shin WW, Shin YK
- KMID: 2093219
- Korean Circ J.
- 1987 Sep;17(3):519-525.
- doi: 10.4070/kcj.1987.17.3.519
We evaluated the clinical effects of Nicorandil in 27 patients (17 male and 10 female) with ischemic heart disease (17 patients of stable effort angina, 3 patients of unstable effort... -
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- Nicorandil alleviated cardiac hypoxia/reoxygenation-induced cytotoxicity via upregulating ketone body metabolism and ACAT1 activity
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Bai YP, Han LS
- KMID: 2443614
- Korean J Physiol Pharmacol.
- 2019 Jan;23(1):37-45.
- doi: 10.4196/kjpp.2019.23.1.37
To study the effect of nicorandil pretreatment on ketone body metabolism and Acetyl-CoA acetyltransferase (ACAT1) activity in hypoxia/reoxygenation (H/R)-induced cardiomyocytes. In our study, we applied H9c2 cardiomyocytes cell line to... -
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- The Effects of Nicorandil on Angina Pectoris: Evaluation by a Double-Blind Cross-Over Study
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Lee WK, Shin GJ, Jang YS, Park KS, Chung NS, Cho SY, Shim WH
- KMID: 2145753
- Korean Circ J.
- 1986 Mar;16(1):103-112.
- doi: 10.4070/kcj.1986.16.1.103
The effect of oral nicorandil were evaluated by a 9-day double-blind cross-over protocol on 16 subjects with angina pectoris referred to our cardiology clinic from June '84 through September '85.... -
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- Hemodynamic Effect of Nicorandil into Pulmonary Artery in Coronary Artery Disease
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Choi BJ, Kim SK, Han DH, Park SH, Bang DW, Kang JH, Kim MK, Byun JD, Shim KH, On YK, Hyon MS, Kwon YJ
- KMID: 1938916
- Korean Circ J.
- 2001 Dec;31(12):1267-1273.
- doi: 10.4070/kcj.2001.31.12.1267
BACKGROUND AND OBJECTIVES: Nicorandil has pharmacologic effects similar to nitroglycerin and potassium in respect to the channel opening action in vascular smooth muscle cells. We examined hemodynamic changes in patients... -
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- Comparison of the Effects of Nicorandil and Cocktail Solution to Prevent Radial Artery Spasm during Coronary Angiography
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Kim SH, Kim EJ, Kim MK, Yun IS, Park WJ, Han SJ, Cho GY, Choi YJ, Hong KS, Han KR, Oh DJ, Rhim CY
- KMID: 2093961
- Korean Circ J.
- 2006 Feb;36(2):133-139.
- doi: 10.4070/kcj.2006.36.2.133
BACKGROUND AND OBJECTIVES: A radial artery spasm is one of the most common complications of coronary angiography during a transradial, causing considerable patient discomfort, which sometimes disturbs the procedure. This... -
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- The Effect of Intra-coronary Nicorandil Prior to Reperfusion in Acute ST Segment Elevation Myocardial Infarction
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An SG, Park TI, Hwang KW, Choi JH, Lee TK, Lee HC, Kim J, Kim JH, Chun KJ, Hong TJ, Shin YW
- KMID: 2225844
- Korean Circ J.
- 2008 Feb;38(2):95-100.
- doi: 10.4070/kcj.2008.38.2.95
BACKGROUND AND OBJECTIVES: Intravenous nicorandil infusion with percutaneous coronary intervention (PCI) has been reported to reduce reperfusion injury events and to improve cardiac function in patients with an acute myocardial... -
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- The Clinical Effects and Radial Artery Vasodilation After High Dose Nicorandil Solution During Coronary Angiography via the Radial Artery
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Cho YC, Kim W, Kim JT, Jeong AD, Cho SC, Kang WY, Whang SH, Kim W
- KMID: 2225816
- Korean Circ J.
- 2008 Apr;38(4):191-196.
- doi: 10.4070/kcj.2008.38.4.191
BACKGROUND AND OBJECTIVES: A spasm of the radial artery is one of the most common complications of coronary angiography (CAG) via the transradial approach (TR), and this spasm sometimes disturbs... -
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- Comparison between Nicorandil and Adenosine in the Measurement of Coronary Flow Reserve Using a Doppler Guide Wire
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Jung HO, Seung KB, Kim PJ, Ihm SH, Kang DH, Youn HJ, Chae JS, Kim JH, Hong SJ, Choi KB
- KMID: 2227266
- Korean Circ J.
- 2002 May;32(5):391-397.
- doi: 10.4070/kcj.2002.32.5.391
BACKGROUND AND OBJECTIVES: Coronary flow reserve (CFR) is the capability of coronary arteriolar bed to dilate in response to increased cardiac metabolic demand. Nocorandil, a hybrid of ATP-sensitive K+ channel... -
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- The Cardioprotective Effect of Intravenous Nicorandil for Ischemia/Reperfusion Injury
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Rim SJ, Hong GR, Im JW, Min PK, Mun JY, Seo HS, Chung N
- KMID: 2093917
- Korean Circ J.
- 2005 Jan;35(1):88-93.
- doi: 10.4070/kcj.2005.35.1.88
BACKGROUND AND OBJECTIVES: Nicorandil is a potassium channel opener, and it has been known to have a cardioprotective effect against ischemia/reperfusion injury. However, the exact mechanisms of the effect are... -
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- The Effect of Nicorandil on the Pharmacodynamics of Rocuronium
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Lee SI, Lee JH, Lee SC, Lee JM
- KMID: 2092093
- Korean J Anesthesiol.
- 2006 May;50(5):567-571.
- doi: 10.4097/kjae.2006.50.5.567
BACKGROUND: Some investigators have shown that nicorandil, a K(ATP) channel opener, depresses the neuromuscular transmission contraction of the skeletal muscle. However, others have reported that it improves the recovery of... -
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- No-Reflow Phenomenon During Treatment of Coronary In-Stent Restenosis With a Paclitaxel-Coated Balloon Catheter
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Chung HH, Moon KW, Jung MH, Yang HK, Park KS, Yoo KD
- KMID: 1433865
- Korean Circ J.
- 2012 Jun;42(6):431-433.
- doi: 10.4070/kcj.2012.42.6.431
Drug-eluting balloon (DEB) with angioplasty a paclitaxel-coated balloon catheter is an effective treatment option in patients with in-stent restenosis (ISR) after a drug-eluting stent (DES). We describe a case in... -
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- A Case of Successful Recovery from High Dose Intravenous Nicorandil Infusion in Refractory Coronary Vasospasm with Hemodynamic Collapse
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Koh WJ, Cho JH, Lee JH, Kang WS, Lee MK, Kim JH, Cho DK
- KMID: 2049813
- Yeungnam Univ J Med.
- 2012 Dec;29(2):129-131.
- doi: 10.12701/yujm.2012.29.2.129
A 70-year-old male came to the emergency room of the authors' hospital because of sudden cardiac arrest due to inferior wall ST elevation myocardial infarction. His coronary angiography revealed multiple... -
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- Myocardial protective effects of nicorandil and verapamil during ischemia-reperfusion in an isolated perfused rat heart
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Kim HS, Cho YK, Kim BS, Kim SO
- KMID: 2046780
- Anesth Pain Med.
- 2008 Oct;3(4):270-276.
BACKGROUND: To reduce or prevent myocardial injury during an ischemia-reperfusion episode, some pharmacological interventions, including administering nicorandil or verapamil, have becomepopular in clinical situations. Nicorandil is a N-(2-hydroxyethyl)- nicotinamide nitrate... -
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- Preventive Effect of Pretreatment with Intravenous Nicorandil on Contrast-Induced Nephropathy in Patients with Renal Dysfunction Undergoing Coronary Angiography (PRINCIPLE Study)
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Ko YG, Lee BK, Kang WC, Moon JY, Cho YH, Choi SH, Hong MK, Jang Y, Kim JY, Min PK, Kwon HM, PRINCIPLE Investigators
- KMID: 2158232
- Yonsei Med J.
- 2013 Jul;54(4):957-964.
- doi: 10.3349/ymj.2013.54.4.957
PURPOSE: To investigate the effect of pretreatment with intravenous nicorandil on the incidence of contrast-induced nephropathy (CIN) in patients with renal dysfunction undergoing coronary angiography. MATERIALS AND METHODS: This randomized controlled... -
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- A Systematic Review on Drug Safety for Molsidomine, Nicorandil and Trimetazidine
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Jeong KH, Lee E
- KMID: 2358069
- Korean J Clin Pharm.
- 2016 Jun;26(2):172-180.
- doi: 10.0000/kjcp.2016.26.2.172
BACKGROUND: Ischemic heart disease is the most common type of heart disease and an important cause of death in Korea. Among marketed anti-anginal medications, molsidomine, nicorandil, and trimetazidine are approved... -
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- Influence of Nicorandil on Catecholamine Release in the Perfused Rat Adrenal Medulla
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Koh YY, Lee ES, No HJ, Woo SC, Chung JW, Seoh YS, Lim DY
- KMID: 2285332
- Korean J Physiol Pharmacol.
- 2007 Jun;11(3):97-106.
The present study was attempted to investigate the effect of nicorandil, which is an ATP-sensitive potassium (KATP) channel opener, on secretion of catecholamines (CA) evoked by cholinergic stimulation and membrane... -
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- The Clinical Effects of Nicorandil during Percutaneous Coronary Intervention in Patients with Unstable Angina
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Kim JH, Jeong MH, Lim SY, Lee SH, Lee YS, Yoon KH, Kang DG, Kim KH, Hong YJ, Park HW, Park OY, Kim W, Ahn YK, Cho JG, Park JC, Kang JC
- KMID: 2029736
- Korean Circ J.
- 2005 Apr;35(4):322-327.
- doi: 10.4070/kcj.2005.35.4.322
BACKGROUND AND OBJECTIVES: The purpose of the study was to evaluate the clinical effect of Nicorandil during percutaneous coronary intervention (PCI) in patients with unstable angina (UA). SUBJECTS AND METHODS:... -
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