- Neuroprotective Effect of Citicoline on Retinal Cell Damage Induced by Kainic Acid in Rats
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Han YS, Chung IY, Park JM, Yu JM
- KMID: 754428
- Korean J Ophthalmol.
- 2005 Sep;19(3):219-226.
- doi: 10.3341/kjo.2005.19.3.219
PURPOSE: To examine whether citicoline has a neuroprotective effect on kainic acid (KA) -induced retinal damage. METHODS: KA (6 nmol) was injected into the vitreous of rat eyes. Citicoline (500mg/kg,... -
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- Neuroprotective effects of Vitis vinifera extract on prediabetic mice induced by a high-fat diet
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Jin HY, Cha YS, Baek HS, Park TS
- KMID: 1780106
- Korean J Intern Med.
- 2013 Sep;28(5):579-586.
- doi: 10.3904/kjim.2013.28.5.579
BACKGROUND/AIMS: Vitis vinifera grape seed extract (VVE) contains oligomeric proanthocyanidins that show antioxidant and free radical-scavenging activities. We evaluated VVE for its neuroprotective effect in prediabetic mice induce by a... -
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- Neuroprotective Effect of Cycloheximide on Hypoxic-Ischemic Brain Injury in Neonatal Rats
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Park WS, Sung DK, Kang S, Koo SH, Kim YJ, Lee JH, Chang YS, Lee M
- KMID: 1781846
- J Korean Med Sci.
- 2006 Apr;21(2):337-341.
- doi: 10.3346/jkms.2006.21.2.337
This study was done to determine the neuroprotective effect of cycloheximide on neonatal hypoxic-ischemic brain injury. Seven day-old newborn rat pups were subjected to 90 min of 8% oxygen following... -
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- KR-31543 reduces the production of proinflammatory molecules in human endothelial cells and monocytes and attenuates atherosclerosis in mouse model
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Choi JH, Yoo JY, Kim SO, Yoo SE, Oh GT
- KMID: 1402317
- Exp Mol Med.
- 2012 Dec;44(12):733-739.
KR-31543, (2S, 3R, 4S)-6-amino-4-[N-(4-chlorophenyl)-N-(2-methyl-2H-tetrazol-5-ylmethyl) amino]-3,4-dihydro-2-dimethyoxymethyl-3-hydroxy-2-methyl-2H-1-benz opyran is a new neuroprotective agent for ischemia-reperfusion damage. It has also been reported that KR-31543 has protective effects on lipid peroxidation and H2O2-induced reactive... -
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- Effects of alpha-Phenyl-N-tert-Butyl Nitrone (PBN)on Brain Cell Membrane Function and Energy Metabolism during Transient Global Cerebral Hypoxia-Ischemia and Reoxygenation-Reperfusion in Newborn Piglets
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Choi CW, Hwang JH, Chang YS, Shin SM, Park WS, Lee M
- KMID: 1786821
- J Korean Med Sci.
- 2004 Jun;19(3):413-418.
- doi: 10.3346/jkms.2004.19.3.413
We sought to know whether a free radical spin trap agent, alpha-phenyl-N-tert-butyl nitrone (PBN) influences brain cell membrane function and energy metabolism during and after transient global hypoxia-ischemia (HI) in... -
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