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Inhibition of melanogenesis by sodium 2-mercaptoethanesulfonate

Kim JH, Oh CT, Kwon TR, Kim JH, Bak DH, Kim H, Park WS, Kim BJ

Sodium 2-mercaptoethanesulfonate (mesna) is a protective agent that is widely used in medicine because of its antioxidant effects. Recently, reactive oxygen species (ROS) were shown to increase pigmentation. Thus, ROS...
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Thyroid-Associated Orbitopathy: Evaluating Microstructural Changes of Extraocular Muscles and Optic Nerves Using Readout-Segmented Echo-Planar Imaging-Based Diffusion Tensor Imaging

Chen HH, Hu H, Chen W, Cui D, Xu XQ, Wu FY, Yang T

OBJECTIVE: We aimed to investigate the ability of readout-segmented echo-planar imaging (rs-EPI)-based diffusion tensor imaging (DTI) in assessing the microstructural change of extraocular muscles (EOMs) and optic nerves in patients...
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Prediction Model for Nursing Work Outcome of Nurses: Focused on Positive Psychological Capital

Lee SN, Kim JA

PURPOSE: The purpose of this study was to construct and test a structural equation model on nursing work outcomes based on Youssef and Luthans' positive psychological capital and integrated conceptual...
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Relationship between job stress, health functional food selection attributes, and consumption values among workers for information technology in Gyeonggi area

Jung JE, Kim SE

PURPOSE: This study examined the relationship between job stress, attributes of health functional food (HFF) selection, and consumption values for information technology (IT) workers, and analyzed the factors influencing the...
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A Structural Model Explaining the Health Behaviors among Adults with Metabolic Syndrome: Theory of Planned Behavior Approach

Jang T, Song R

PURPOSE: This study aimed to identify the factors explaining the performance of health behaviors among adults with metabolic syndrome based on the theory of planned behavior. METHODS: A total of 218...
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Mediating Effects of Self-Care Competence on the Relationship between Uncertainty and Quality of Life in Hemodialysis Patients

Chae YJ, Ahn JH, Kang KP, Jo E

PURPOSE: This study aimed to explore the mediating effect of self-care competence on the relationships between uncertainty, self-care competence, and quality of life in patients undergoing hemodialysis. METHODS: This study used...
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Mediating Effects of Resilience between Nurse's Character and Happiness for Nurses in General Hospitals

Han S, Oh J, Huh B, Kim H

PURPOSE: This study was done to identify the mediating effect of resilience on the relationship between nurse's character and happiness for nurses in general hospitals. METHODS: Participants were 139 nurses working...
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Effects of Gamma-Glutamyl Transferase on Stroke Occurrence Mediated by Atrial Fibrillation

Yang W, Kang DW, Lee SH

BACKGROUND AND PURPOSE: Gamma-glutamyl transferase (GGT) is reported to be associated with stroke independently of the conventional risk factors. However, the underlying mechanism remains to be identified. This study focused...
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Ezrin-radixin-moesin proteins are regulated by Akt-GSK3β signaling in the rat nucleus accumbens core

Kim WY, Cai WT, Jang JK, Kim JH

The ezrin-radixin-moesin (ERM) proteins are a family of membrane-associated proteins known to play roles in cell-shape determination as well as in signaling pathways. We have previously shown that amphetamine decreases...
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Reviews on the Hepatotoxicity of Tyrosine Kinase Inhibitors

Han JM, Gwak HS

BACKGROUND: Small-molecule tyrosine kinase inhibitors (TKIs) have had major impacts on anticancer therapy by targeting the catalytic activities of dysregulated tyrosine kinases. TKIs have not presented traditional toxicities; however, some...
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Factors Affecting of Relevance Index of the Regional Public Hospital: Focused on Refined Diagnosis-Related Group Impacts

Yoon A, Woo KS, Shin YJ

BACKGROUND: An important function of the regional public hospital is to satisfy the basic medical needs of the community through the stable provision of high-quality medical services. The purpose of...
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Mechanisms and therapeutic targets of ischemic acute kidney injury

Han SJ, Lee HT

Acute kidney injury (AKI) due to renal ischemia reperfusion (IR) is a major clinical problem without effective therapy and is a significant and frequent cause of morbidity and mortality during...
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Effects of Emotional Intelligence and Nursing Working Environment on Nursing Performance of Nurses Caring for Cancer Patients in Small and Medium Hospitals: The Mediating Effect of Communication Competence

Kang YJ, Jung KI

PURPOSE: The purpose of this study was to investigate whether the effects of emotional intelligence and working environment on nursing performance of nurses caring for cancer patients in small and...
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Mediating Effect of Meaning in Life on the Relationship between Social Connectedness and Depression among Middle-aged Women

Son JA, Kim J, Hyun MS

PURPOSE: This study was conducted to examine the mediating effect of meaning in life on the relationship between social connectedness and depression among middle-aged women. METHODS: A descriptive correlational design was...
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The Effect of Workplace Violence on Depressive Symptoms and the Mediating Role of Psychological Capital in Chinese Township General Practitioners and Nurses: A Cross-Sectional Study

Tong C, Cui C, Li Y, Wang L

OBJECTIVE: The most existing research has predominantly focused on city rather than township hospitals. This study aimed to explore depressive symptoms and its associated factors among general practitioners and nurses...
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Mediation Effects of Basic Psychological Needs Between Autonomy Support from Healthcare Providers and Self-Management Among Cancer Survivors

Bae EJ, Kim YH

OBJECTIVES: This study examined the mediating effects of basic psychological needs between patient autonomy support from healthcare providers, and self-management among cancer survivors. METHODS: This study collected data from 148 cancer...
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A Literature Review of Research on Leadership of Korean Hospital Nurse

Kim S, Seo MH, Jeong SH, Kim HS, Kim YL

PURPOSE: This study was done to identify trends in leadership-related research by reviewing studies on hospital nurses in South Korea. METHODS: The research was conducted from April 2 to 14, 2018...
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A Critical Role of PCSK9 in Mediating IL-17-Producing T Cell Responses in Hyperlipidemia

Kim YU, Kee P, Danila D, Teng BB

We previously demonstrated that atherogenic Ldlr(−/−)Apobec1(−/−) (LDb) double knockout mice lacking both low-density lipoprotein receptor (LDLR) and apolipoprotein B mRNA-editing catalytic polypeptide-1 (Apobec1) had increased serum IL-17 levels, with T...
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Mediating Effect of Physical Activity in the Relationship between Depressive Symptoms and Health-related Quality of Life in Patients with Coronary Artery Disease: The 2016 Nationwide Community Health Survey in Korea

Won MH

PURPOSE: This study aimed to examine the mediating role of physical activity in the relationship between depressive symptoms and health-related quality of life in patients with coronary artery disease. METHODS: A...
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Mediating Effects of Health Belief on the Correlations among Disease-related Knowledge, eHealth Literacy, and Self-care Behaviors in Outpatients with Hypertension

Cho GY, Ha MN

PURPOSE: This study aimed to identify the mediating effects of health belief on the disease-related knowledge, eHealth literacy, and self-care behavior of hypertension patients. eHealth is an emerging field of...
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