- Stereoselective Microbial Hydroxylation of Progestin, Norethisterone by Using Aspergillus niger and Penicillium citrinum
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A, Iqbal M, Musharraf SG, Shahzad S
- KMID: 2511946
- Nat Prod Sci.
- 2020 Dec;26(4):283-288.
- doi: 10.20307/nps.2020.26.4.283
Microbial transformation of a potent progestin, norethisterone (17β-hydroxy-19-nor-17α-pregn-4-en-20-yn-3-one) (1) was carried out by using two filamentous fungi Aspergillus niger and Penicillium citrinum. Biotransformation of 1 with A. niger yielded a hydroxylated... -
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- A New Coumestan Glucoside from Eclipta prostrata
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Seo YJ, Kil HW, Rho T, Yoon KD
- KMID: 2511947
- Nat Prod Sci.
- 2020 Dec;26(4):289-294.
- doi: 10.20307/nps.2020.26.4.289
Eclipta prostrata is an annual herb, belonging to Asteraceae family, and has been traditionally used to improve immunity and treat hepatitis and bacterial disease in Korea. In this study, a... -
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- A New Cytotoxic Compound from Methanol Extract of Koordersiodendron pinnatum Merr. Leaves
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Fajriah S, Megawati M, Darmawan A, Lotulung PDN, Salahuddin S, Hanafi M
- KMID: 2511945
- Nat Prod Sci.
- 2020 Dec;26(4):279-282.
- doi: 10.20307/nps.2020.26.4.279
Chemical investigation of the methanol extract of Koordersiodendron pinnatum Merr. leaves resulted a new naphthalene derivative, (Z)-4-(tetradec-3-enyl)naphthalene-1,2,7-triol (1), together with three known compounds, β-sitosterol (2), 20-epibryonolic acid (3), and scopoletin... -
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- Calyxaprenols A-D, New Merohexaprenoid Metabolites from the Marine Sponge Calyx sp.
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Kim CK, Gustafson KR
- KMID: 2511949
- Nat Prod Sci.
- 2020 Dec;26(4):303-310.
- doi: 10.20307/nps.2020.26.4.303
Four new merohexapenoids named calyxaprenols A-D (1 - 4), together with the known compound haliclotriol A (5), have been isolated from the marine sponge Calyx sp. which was collected from... -
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- Snake Venom Phospholipase A2 and its Natural Inhibitors
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Singh P, Yasir M, Khare R, Tripathi MK, Shrivastava R
- KMID: 2511943
- Nat Prod Sci.
- 2020 Dec;26(4):259-267.
- doi: 10.20307/nps.2020.26.3.259
Snakebite is a severe medical, economic, and social problem across the world, mostly in the tropical and subtropical area. These regions of the globe have typical of the world's venomous... -
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- Molecular Networking-based De-replication Strategy Leads to the Isolation of a New Chromone from Pleosporales sp.
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Kwon H, Kim JG, Oh JJ, Kim JJ, Kim GH, Hwang BY, Yim JH, Lee D
- KMID: 2511963
- Nat Prod Sci.
- 2020 Dec;26(4):340-344.
- doi: 10.20307/nps.2020.26.4.340
A new chromone analogue (1) was isolated from an EtOAc-extract of Pleosporales sp. culture medium, together with five known chromones (2 – 6). The isolation workflow was guided by... -
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- Antiplatelet Effect of Cudraxanthone L Isolated from Cudrania tricuspidata via Inhibition of Phosphoproteins
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Shin JH, Rhee MH, Kwon HW
- KMID: 2511948
- Nat Prod Sci.
- 2020 Dec;26(4):295-302.
- doi: 10.20307/nps.2020.26.4.295
Cudrania tricuspidata (C. tricuspidata) is a deciduous tree found in Japan, China and Korea. The root, stems, bark and fruit of C. tricuspidata has been used as traditional herbal remedies... -
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- Four Dammarane Triterpenes and Their Inhibitory Properties Against Eight Receptor Tyrosine Kinases
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Heliawati L, Khatimah H, Hermawati E, Syah YM
- KMID: 2511967
- Nat Prod Sci.
- 2020 Dec;26(4):345-350.
- doi: 10.20307/nps.2020.26.4.345
In recent years, tyrosine kinases (TKs) have been the target to combat cancers, and most of the developed inhibitors are of synthetic origin. Natural compounds that have the properties as... -
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- Lanostane Triterpenoids from Ganoderma tropicum Collected in Vietnam and Their Nitroblue Tetrazolium Reductive Activity In Vitro
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Duyen NT, Khoi NM, Truong Thang PN, Tan DM, Hung TV, Ha DT
- KMID: 2511960
- Nat Prod Sci.
- 2020 Dec;26(4):334-339.
- doi: 10.20307/nps.2020.26.4.334
A new compound, 3β-acetoxylanosta-7,9(11),24-triene-26-al (3), and seven known compounds (1 – 2 and 4 – 8) were isolated from Ganoderma tropicum (Jung.) Bres. collected in Tay Nguyen, Vietnam. The structures... -
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- Development and Validation of an HPLC-PDA Method for Quantitation of Ten Marker Compounds from Eclipta prostrata (L.) and Evaluation of Their Protein Tyrosine Phosphatase 1B, α-Glucosidase, and Acetylcholinesterase Inhibitory Activities
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Nguyen DH, Le DD, Ma ES, Min BS, Woo MH
- KMID: 2511958
- Nat Prod Sci.
- 2020 Dec;26(4):326-333.
- doi: 10.20307/nps.2020.26.4.326
The aerial parts of Eclipta prostrata is used as a traditional medicine and vegetable. In traditional folk medicine, it is used for treatment of hemorrhages, hepatic, disease, renal injuries, hair... -
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- Chemical Composition of Artemisia argyi Extract (RW0117) and Protective Effects against Gastric Lesions in vivo
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Lee JW, Park SH, Jegal CM, Choi KY, Jung HY, Choi JA, Lee CK, Kim HK, Lee JS, Lee IK
- KMID: 2511944
- Nat Prod Sci.
- 2020 Dec;26(4):268-278.
- doi: 10.20307/nps.2020.26.4.268
In this study, we investigated the chemical profile and effects of RW0117 (Artemisia argyi 65 .5 % ethanol extract) on gastric lesions in rats. We optimized and validated a method... -
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- Chemicals Constituents from Leaves of Diospyros iturensis (Gürke) Letouzey & F. White and their Biological Activities
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Feumo Feusso HM, Dongmo Jdd, Djomkam HLM, Akak CM, Lateef M, Ahmed A, Blaise Azebaze AG, Kamdem Waffo AF, Shaiq Ali M, Vardamides JC
- KMID: 2511951
- Nat Prod Sci.
- 2020 Dec;26(4):311-316.
- doi: 10.20307/nps.2020.26.4.311
he chemical investigation of the methanolic crude extract of leaves of Diospyros iturensis gave us 15 known secondary metabolites identified as mixture of α-amyrenone (1) and β-amyrenone (2), β-amyrin (3),... -
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- A New Stilbene Dimer and Other Chemical Constituents from Monanthotaxis littoralis with Their Antimicrobial Activities
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Nguetse Dongmo AJ, Ekom SE, Tamokou edD, Tagousop CN, Harakat D, Voutquenne-Nazabadioko L, Ngnokam D
- KMID: 2511955
- Nat Prod Sci.
- 2020 Dec;26(4):317-325.
- doi: 10.20307/nps.2020.26.4.317
A new dimer stilbene [Monalittorin (1)] and ten known compounds [engeletin (2), aurantiamide acetate (3), lupeol (4), friedelin (5), quercetin (6), tiliroside (7), rutoside (8), astragalin (9), isoquercitrin (10) and... -
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