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Back out of Locking Pin with Hinge Fracture after High Tibial Osteotomy

Otsuki S, Murakami T, Morikura R, Nakagawa K, Okamoto Y, Neo M

Low-profile fixation devices for medial opening wedge high tibial osteotomy (OWHTO) were developed in order to avoid skin irritation and additional invasion. However, the low-profile system is associated with additional...
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200 mL Rapid Drink Challenge During High-resolution Manometry Best Predicts Objective Esophagogastric Junction Obstruction and Correlates With Symptom Severity

Woodland P, Gabieta-Sonmez S, Arguero J, Ooi J, Nakagawa K, Glasinovic E, Yazaki E, Sifrim D

  • KMID: 2417385
  • J Neurogastroenterol Motil.
  • 2018 Jul;24(3):410-414.
  • doi: 10.5056/jnm18038
BACKGROUND/AIMS: Single swallow integrated relaxation pressure (IRP) on high-resolution manometry (HRM) does not always accurately predict esophagogastric outflow obstruction on timed barium esophagogram (TBE). Furthermore, neither single swallow IRP or...
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Neural Mechanisms of Discogenic Back Pain: How Does Nerve Growth Factor Play a Key Role?

Aoki Y, Ohtori S, Nakagawa K, Nakajima A, Inoue G, Miyagi M, Takahashi

It was reported that nerve fibers were present in the inner part of lumbar intervertebral discs from patients with discogenic pain. Because there are no nerve fibers in the inner...
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A single immunization with recombinant rabies virus (ERAG3G) confers complete protection against rabies in mice

Yang DK, Nakagawa K, Ito N, Kim HH, Hyun BH, Nah JJ, Sugiyama M, Song JY

PURPOSE: New alternative bait rabies vaccines applicable to pet dogs and wild animals are needed to eradicate rabies in Korea. In this study, recombinant rabies virus, ERAG3G strain was constructed...
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Transesophageal Echocardiographic Findings Are Independent and Relevant Predictors of Ischemic Stroke in Patients with Nonvalvular Atrial Fibrillation

Takashima , Nakagawa K, Hirai T, Dougu N, Taguchi Y, Sasahara E, Ohara K, Fukuda N, Inoue H, Tanaka K

BACKGROUND AND PURPOSE: Not only clinical factors, including the CHADS2 score, but also echocardiographic findings have been reported to be useful for predicting the risk of ischemic stroke in patients...
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Details of recurrence sites after definitive radiation therapy for cervical cancer

Kobayashi , Yamashita , Okuma K, Ohtomo K, Nakagawa K

OBJECTIVE: This is a retrospective study aimed at clarifying the details of recurrence patterns and sites in patients with cervical cancer treated with definitive radiation therapy (RT). METHODS: Data were analyzed...
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Assessment of the Initial Diagnostic Accuracy of a Fragility Fracture of the Sacrum: A Study of 56 Patients

Umeda R, Iijima Y, Yamakawa N, Kotani T, Sakuma T, Kishida S, Ueno K, Kajiwara D, Akazawa T, Shiga Y, Minami S, Ohtori S, Nakagawa K

Study Design: Retrospective study. Purpose: To investigate the clinical manifestations of a fragility fracture of the sacrum (FFS) and the factors that may contribute to a misdiagnosis. Overview of Literature: The number...
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Existence of a Neuropathic Pain Component in Patients with Osteoarthritis of the Knee

Ohtori S, Orita S, Yamashita , Ishikawa T, Ito T, Shigemura , Nishiyama , Konno S, Ohta H, Takaso M, Inoue G, Eguchi Y, Ochiai N, Kishida S, Kuniyoshi , Aoki Y, Arai G, Miyagi M, Kamoda H, Suzkuki M, Nakamura J, Furuya T, Kubota G, Sakuma Y, Oikawa Y, Suzuki M, Sasho T, Nakagawa K, Toyone T, Takahashi

PURPOSE: Pain from osteoarthritis (OA) is generally classified as nociceptive (inflammatory). Animal models of knee OA have shown that sensory nerve fibers innervating the knee are significantly damaged with destruction...
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Pemetrexed Continuation Maintenance in Patients with Nonsquamous Non-small Cell Lung Cancer: Review of Two East Asian Trials in Reference to PARAMOUNT

Yang JC, Ahn MJ, Nakagawa K, Tamura T, Barraclough H, Enatsu S, Cheng R, Orlando M

PURPOSE: A recent phase III study (PARAMOUNT) demonstrated that pemetrexed continuation maintenance therapy is a new treatment paradigm for advanced nonsquamous non-small cell lung cancer (NSCLC). The majority of patients...
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Crizotinib versus Chemotherapy in Asian Patients with ALK-Positive Advanced Non-small Cell Lung Cancer

Nishio M, Kim DW, Wu YL, Nakagawa K, Solomon BJ, Shaw AT, Hashigaki , Ohki E, Usari T, Paolini J, Polli A, Wilner KD, Mok T

PURPOSE: Crizotinib has demonstrated superior progression-free survival (PFS) and objective response rates (ORRs) versus chemotherapy in previously treated and untreated patients with anaplastic lymphoma kinase (ALK)-positive advanced non-small cell lung...
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