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Endogenous Nitric Oxide Inhibits Na,K-ATPase Activity in the Kidney

Kim JW, Kang DG

  • KMID: 2172466
  • Chonnam Med J.
  • 1999 Dec;35(4):553-562.
Nitric oxide (NO) has been suggested to play a role in regulating sodium excretion in the kidney. The present study was aimed at investigating the effect of endogenous NO system...
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Role of Nitric Oxide on the Proliferation of Human Tenon Capsule Fibroblasts

Kim KH, Kim JW

  • KMID: 2125582
  • J Korean Ophthalmol Soc.
  • 2003 Jul;44(7):1670-1674.
PURPOSE: To investigate the role of nitric oxide(NO) on the survival and proliferation of human Tenon capsule fibroblasts(HTCF) in tissue culture. METHODS: Following exposure to NO donor such as sodium...
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The Ototoxicity of Cisplatin is Mediated by NO: A Study using L-NAME and MK-801 in Guinea pigs

Rhee CK, Oh YH, Jeon SJ, Chung SY, Oh CH

  • KMID: 2275942
  • Korean J Otolaryngol-Head Neck Surg.
  • 2002 Aug;45(8):741-746.
BACKGROUND AND OBJECTIVES: Nitric oxide has been suggested to play an important role in the pathogenesis of cisplatin ototoxicity. L-NAME (NG-Nitroarginine Methyl Ester) is an inhibitor of nitric oxide synthase....
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Effect of Nitric Oxide on the Survival of R28 Cells

Lee JI, Kim JW

PURPOSE: To evaluate the effect of nitric oxide (NO) on the survival of R28 cells. METHODS: After immunostaining for GFAP, vimentin, S-100, and neurofilament, R28 cells were exposed to S-nitroso-N-acetyl-D, L-penicillamine...
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Effect of Nitric Oxide on the Permeability of Trabecular Meshwork Cell Monolayer

Kim HY, Kim JW

PURPOSE: To investigate the effects of nitric oxide (NO) on the permeability of cultured human trabecular meshwork cell (HTMC) monolayer. METHODS: HTMCs were cultured until confluency in the Transwell inner chamber...
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Effects of Nitric Oxide Synthesis Inhibition on the Blood Pressure Response to Bradykinin in Rats

Yeum CH, Yang MJ, Jun JY, Yoon PJ, Moon SH, Kim JH, Lee JU

  • KMID: 2079020
  • Korean J Nephrol.
  • 1998 Sep;17(5):667-672.
Bradykinin has been known to elicit a pressor effect when administered centrally, and a depressor effect when administered peripherally. The present study was aimed at investigating whether the blood pressure...
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The Antinociceptive Effect of Intraperitoneally Administered Nonselective Nitric Oxide Synthase Inhibitor on the Rat Formalin Test

Oh M, Lee W, Go Y

BACKGROUND: Nitric oxide (NO) is involved in the transmission and modulation of nociceptive information at the peripheral, spinal cord and supraspinal levels. We conducted this experiment to assess the...
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Nitric Oxide-Mediated Neurotoxicity after Excimer Laser Photorefractive Keratectomy

Joo MJ, Lee KJ, Shin KH, Kim JC

  • KMID: 2205473
  • J Korean Ophthalmol Soc.
  • 1999 Mar;40(3):688-698.
The aim of this study was to evaluate neurotoxicity of Nitric oxide(NO) on cornea after excimer laser photorefractive keratectomy(PRK). PRK was performed on rabbit eyes. According to the time table,...
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Effect of NG-nitro-L-arginine Methyl Ester Pretreatment on Spinal Cord Damage by Aortic Occlusion in Rabbits

Lee JY, Min JH, Kim DU, Park CJ

BACKGROUND: Production of nitric oxide (NO) radicals may contribute to neuronal injury. We examined that the inhibition of NO synthase (NOS) could improve postischemic neurologic outcome after spinal cord ischemia...
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Effect of Hypoxia on the Survival and Production of Nitric Oxide in Trabecular Meshwork Cells

Jin YH, Kim JW

  • KMID: 2125788
  • J Korean Ophthalmol Soc.
  • 2004 Dec;45(12):2127-2132.
PURPOSE: To investigate the effect of hypoxia on the survival and nitric oxide (NO) production of cultured trabecular meshwork (TM) cells. METHODS: After inducing chemical hypoxia with sodium cyanide, the...
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Protective mechanism of nitric oxide and mucus against ischemia/reperfusion-induced gastric mucosal injury

Kim H, Nam K, Kim KH

  • KMID: 2285214
  • Korean J Physiol Pharmacol.
  • 1998 Aug;2(4):511-519.
This study investigated the role of nitric oxide on the oxidative damage in gastric mucosa of rats which received ischemia/reperfusion and its relation to mucus. Nitric oxide synthesis modulators such as L-arginine and...
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The Effect of Nitric Oxide on Mechanical and Theraml Allodynia in Neuropathic Pain Model of Rat

Kim SH, Jung SJ

  • KMID: 2195075
  • J Korean Neurol Assoc.
  • 2003 Jun;21(3):283-288.
BACKGROUND: Nitric oxide (NO) is known to play causative role in the development of neuropathic pain following peripheral nerve injury. However, it is yet to be investigated whether the role...
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Blunted Indomethacin-Induced Downregulation of Aquaporins by Nitric Oxide Synthesis Inhibition in Rats

You JH, Lee S, Bae EH, Ma SK, Kim SW, Lee JU

  • KMID: 1587400
  • Korean J Physiol Pharmacol.
  • 2006 Aug;10(4):213-216.
The present study was aimed to determine whether nitric oxide (NO) plays a role in the regulation of aquaporin (AQP) channels in the kidney. Male Brattleboro rats (250~300 g body...
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Effect of NG-nitro-L-arginine methyl ester and Methylene Blue on the Endotoxin-induced Vascular Hyporesponsiveness

Choi HC, Ha JH, Lee KY, Kim WJ, Sohn UD

  • KMID: 2320331
  • Yeungnam Univ J Med.
  • 1997 Dec;14(2):337-349.
The study was undertaken to examine the intensity of involvement of inducible nitric oxide synthase(iNOS) and cyclic GMP signal transduction pathway as one of the mechanisms of vaso-relaxative action of...
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Effect of Nitric Oxide on the Proliferation of Cultured Human Tenon Capsule Fibroblasts Exposed to Benzalkonium Chloride

Kim JW, Kim KH, Cho BJ

  • KMID: 2206656
  • J Korean Ophthalmol Soc.
  • 2003 Aug;44(8):1908-1913.
PURPOSE: To investigate whether the effect of benzalkonium chloride (BAK) on the proliferation of human Tenon capsule fibroblasts (HTCF) is mediated by nitric oxide (NO) in tissue culture . METHODS:...
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Effects of Nitric Oxide Synthesis Inhibition on Indomethacin-Induced Downregulation of Renal Aquaporins in Rats

Bae EH, Park CH, Kim SW, Ma SK, Kim NH, Choi KC, Lee JU

  • KMID: 1867691
  • Korean J Nephrol.
  • 2006 Nov;25(6):887-892.
BACKGROUND:The present study aimed to determine whether there is a regulatory mechanism exerted by endogenous nitric oxide (NO) in the regulation of aquaporin (AQP) water channels in the kidney. METHODS:Male Sprague-Dawley...
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The hyperthermic effect of nitric oxide in central nervous system

Jung JK, Sohn UD, Lee SY

  • KMID: 1606844
  • Korean J Physiol Pharmacol.
  • 2001 Feb;5(1):93-98.
The precise mechanism of set-point regulation in hypothalamus was not elucidated. Nitric oxide synthases (NOS) were detected in hypothalamus, however, the roles of NO in hypothalamus was not fully studied. So, we tested...
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Neuroprotective Effects of MK-801 (Dizocilpine) on Bilirubin Neurotoxicity in Mouse Cortical Cell Culture

Hwang JH, Choi CW, Chang YS, Park WS

  • KMID: 1609582
  • Korean J Perinatol.
  • 2004 Mar;15(1):34-40.
OBJECTIVE: To evaluate whether MK-801, N-methyl-D-aspartate (NMDA) receptor antagonist, could protect against bilirubin neurotoxicity in mouse neuronal cells. METHODS: Mouse cerebral cortical cells were obtained from 14 day-old mouse fetal cerebral...
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Blockade of Nitric Oxide Synthesis Further Diminishes Aquaporin Water Channels in Rat Kidney Subjected to Ischemia/reperfusion Injury

Ma SK, Oh YW, Park C, Lee YK, Kim SW, Kim NH, Choi KC, Lee J

  • KMID: 2079573
  • Korean J Nephrol.
  • 2006 Jan;25(1):7-12.
BACKGOUND: The present study examined whether a blockade of nitric oxide (NO) synthesis affects the regulation of aquaporin (AQP) water channels in rats subjected to renal ischemia/reperfusion (I/R). METHODS: Renal...
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L - NAME Inhibits Hyperalgesia Induced by Freund's Complete Adjuvant in Rat Paw

Leem JW, Choi Y, Lee C, Song MH, Lee DM, Raja SN

  • KMID: 2425666
  • J Korean Pain Soc.
  • 1998 Oct;11(2):194-200.
BACKGROUND: Effect of nitric oxide on the hyperalgesia induced by inflammation is controversial. We attempted to find out the peripheral effects of nitric oxide (NO) on hyperalgesia induced by Freund's eomplete...
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