- Animal model evaluation of a novel renal denervation system for future laparoscopic treatment of resistant hypertension
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Song WH, Baik J, Yang S, Choi EK, Park SM, Jeong CW
- KMID: 2466799
- Investig Clin Urol.
- 2020 Jan;61(1):107-113.
- doi: 10.4111/icu.2020.61.1.107
PURPOSE: Although percutaneous catheter-based ablation of renal sympathetic nerve fibers has been used in the treatment of patients with resistant hypertension, a recent phase III study did not confirm its... -
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- Anti-arthritic Effects of Oplopanax elatus in a Rat Model of Rheumatoid Arthritis (Adjuvant-induced Arthritis)
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Kwon KS, Lim H, Kwon YS, Choi HR, Kim MJ, Yoo JH, Yoo NH, Kim HP
- KMID: 2468063
- Nat Prod Sci.
- 2019 Dec;25(4):304-310.
- doi: 10.20307/nps.2019.25.4.304
The stems of Oplopanax elatus (OE) have long been used to treat inflammatory disorders in herbal medicine, and in the previous investigation, OE was found to possess anti-inflammatory activity in... -
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- Influence of clozapine on neurodevelopmental protein expression and behavioral patterns in animal model of psychiatric disorder induced by low-level of lead
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Lee H, Lee M, Kim HK, Kim YO, Kwon JT, Kim HJ
- KMID: 2461039
- Korean J Physiol Pharmacol.
- 2019 Nov;23(6):467-474.
- doi: 10.4196/kjpp.2019.23.6.467
Exposure to lead during pregnancy is a risk factor for the development of psychiatric disorders in the offspring. In this study, we investigated whether exposure to low levels of lead... -
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- Therapeutic Effect of Glucosamine on an Atopic Dermatitis Animal Model
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Yoon HS, Byun JW, Shin J, Kim YH, Choi GS
- KMID: 2456231
- Ann Dermatol.
- 2019 Oct;31(5):538-544.
- doi: 10.5021/ad.2019.31.5.538
BACKGROUND: Recent studies have reported that glucosamine (GlcN) showed therapeutic effects in allergic diseases such as asthma and rhinitis, and its mechanisms include the suppression of T helper type 2... -
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- Treatment with low-energy shock wave alleviates pain in an animal model of uroplakin 3A-induced autoimmune interstitial cystitis/painful bladder syndrome
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Li H, Zhang Z, Peng J, Xin Z, Li M, Yang B, Fang D, Tang Y, Guo Y
- KMID: 2455963
- Investig Clin Urol.
- 2019 Sep;60(5):359-366.
- doi: 10.4111/icu.2019.60.5.359
PURPOSE: To investigate whether treatment with low-energy shock wave (LESW) alleviates pain and bladder dysfunction in a mouse model of uroplakin 3A (UPK3A)-induced interstitial cystitis/painful bladder syndrome (IC/PBS). MATERIALS AND METHODS:... -
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- Effect of gemigliptin on cardiac ischemia/reperfusion and spontaneous hypertensive rat models
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Nam DH, Park J, Park SH, Kim KS, Baek EB
- KMID: 2455809
- Korean J Physiol Pharmacol.
- 2019 Sep;23(5):329-334.
- doi: 10.4196/kjpp.2019.23.5.329
Diabetes is associated with an increased risk of cardiovascular complications. Dipeptidyl peptidase-4 (DPP-IV) inhibitors are used clinically to reduce high blood glucose levels as an antidiabetic agent. However, the effect... -
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- Effect of Ambrisentan Therapy on the Expression of Endothelin Receptor, Endothelial Nitric Oxide Synthase and NADPH Oxidase 4 in Monocrotaline-induced Pulmonary Arterial Hypertension Rat Model
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Lee H, Yeom A, Kim KC, Hong YM
- KMID: 2455794
- Korean Circ J.
- 2019 Sep;49(9):866-876.
- doi: 10.4070/kcj.2019.0006
BACKGROUND AND OBJECTIVES: Elevated endothelin (ET)-1 level is strongly correlated with the pathogenesis of pulmonary arterial hypertension (PAH). Expression level of nicotinamide adenine dinucleotide phosphate oxidase (NOX) 4 is increased... -
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- Quantitative Evaluation of Hepatic Steatosis Using Normalized Local Variance in a Rat Model: Comparison with Histopathology as the Reference Standard
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Bae JS, Lee JY, Lee DH, Kim H, Lee Y, Han JK
- KMID: 2455768
- Korean J Radiol.
- 2019 Sep;20(9):1399-1407.
- doi: 10.3348/kjr.2019.0068
OBJECTIVE: To evaluate the diagnostic performance of the normalized local variance (NLV) ultrasound technique in the assessment of hepatic steatosis, and to identify the factors that influence the NLV value... -
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- Effects of dexamethasone and hydrocortisone on rocuronium-induced neuromuscular blockade and reversal by sugammadex in phrenic nerve-hemidiaphragm rat model
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Choi H, Park SY, Kim YB, In J, Yang HS, Lee JS, Kim S, Park S
- KMID: 2458322
- Korean J Anesthesiol.
- 2019 Aug;72(4):366-374.
- doi: 10.4097/kja.d.18.00238
BACKGROUND: The facilitator effects of steroids on neuromuscular transmission may cause resistance to neuromuscular blocking agents. Additionally, steroids may hinder sugammadex reversal of neuromuscular blockade, but these findings remain controversial.... -
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- Influence of Short- and Long-term High-dose Caffeine Administration on Behavior in an Animal Model of Adolescence
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Park JM, Kim Y, Kim H, Kim YJ
- KMID: 2457602
- J Korean Biol Nurs Sci.
- 2019 Aug;21(3):217-223.
- doi: 10.7586/jkbns.2019.21.3.217
PURPOSE: Caffeine is the most widely consumed psychostimulant of the methylxanthine class. Among adolescents, high-dose of caffeine consumption has increased rapidly over the last few decades due to the introduction... -
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- Therapeutic Effect of 308-nm Excimer Laser on Alopecia Areata in an Animal Model
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Moon JH, Bang CY, Kang MJ, Yeom SD, Yoon HS, Kim HJ, Byun JW, Shin J, Choi GS
- KMID: 2451489
- Ann Dermatol.
- 2019 Aug;31(4):463-466.
- doi: 10.5021/ad.2019.31.4.463
No abstract available. -
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- Polydeoxyribonucleotides Improve Diabetic Wound Healing in Mouse Animal Model for Experimental Validation
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Kwon TR, Han SW, Kim JH, Lee BC, Kim JM, Hong JY, Kim BJ
- KMID: 2451477
- Ann Dermatol.
- 2019 Aug;31(4):403-413.
- doi: 10.5021/ad.2019.31.4.403
BACKGROUND: Wound healing mechanisms is believed to have effects similar to wound healing disorders in diabetic patients, including abnormal inflammatory cells, angiogenesis disorders, and reduced collagen synthesis. Therefore, reestablishment of... -
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- Adipose Tissue-Derived Stem Cell Therapy for Cavernous Nerve Injury-Induced Erectile Dysfunction in the Rat Model: A Systematic Review and Meta-Analysis Using Methodological Quality Assessment
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Park HJ, Jeong H, Park YH, Yim HW, Ha US, Hong SH, Kim SW, Kim NJ, Lee JY
- KMID: 2465892
- Int J Stem Cells.
- 2019 Jul;12(2):206-217.
- doi: 10.15283/ijsc18122
BACKGROUND AND OBJECTIVES: Few studies were evaluated the effect of blindness on outcome in animal models, though a potential effect of blinding has been reported in clinical trials. We evaluated... -
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- Synergistic effects of extracorporeal shockwave therapy and modified Ojayeonjonghwan on erectile dysfunction in an animal model of diabetes
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Jeong HC, Bae WJ, Zhu GQ, Jeon SH, Choi SW, Kim SJ, Cho HJ, Hong SH, Lee JY, Hwang SY, Kim SW
- KMID: 2450546
- Investig Clin Urol.
- 2019 Jul;60(4):285-294.
- doi: 10.4111/icu.2019.60.4.285
PURPOSE: We investigated the synergy effect of extracorporeal shock wave therapy (ESWT) with modified Ojayeonjonghwan (Korean herbal formula, KH-204) in an animal model of diabetes mellitus (DM)-induced erectile dysfunction (ED). MATERIALS... -
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- Supplementation with psyllium seed husk reduces myocardial damage in a rat model of ischemia/reperfusion
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Lim SH, Lee J
- KMID: 2453284
- Nutr Res Pract.
- 2019 Jun;13(3):205-213.
- doi: 10.4162/nrp.2019.13.3.205
BACKGROUND/OBJECTIVES: Myocardial infarction (MI) is caused by extensive myocardial damage attributed to the occlusion of coronary arteries. Our previous study in a rat model of ischemia/reperfusion (I/R) demonstrated that administration... -
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- Effect of Pyunkang-tang on Inflammatory Aspects of Chronic Obstructive Pulmonary Disease in a Rat Model
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Seo HS, Lee HJ, Lee CJ
- KMID: 2452778
- Nat Prod Sci.
- 2019 Jun;25(2):103-110.
- doi: 10.20307/nps.2019.25.2.103
We investigated the anti-inflammatory effect of Pyunkang-tang extract (PGT), a complex herbal extract based on traditional Chinese medicine that is used in Korea for controlling diverse pulmonary diseases, on cigarette... -
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- Effect of Ghrelin on Memory Impairment in a Rat Model of Vascular Dementia
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Park JM, Kim YJ
- KMID: 2451299
- J Korean Acad Nurs.
- 2019 Jun;49(3):317-328.
- doi: 10.4040/jkan.2019.49.3.317
PURPOSE: The purpose of this study was to identify the effect of ghrelin on memory impairment in a rat model of vascular dementia induced by chronic cerebral hypoperfusion. METHODS: Randomized controlled... -
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- The Evaluation of Exogenous Melatonin Administration in Supraspinatus Overuse Tendinopathy in an Experimental Rat Model
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Kocadal O, Pepe M, Akyurek N, Gunes Z, Surer H, Aksahin E, Ogut B, Aktekin CN
- KMID: 2449434
- Clin Should Elbow.
- 2019 Jun;22(2):79-86.
- doi: 10.5397/cise.2019.22.2.79
BACKGROUND: Increased oxidative stress and inflammation play a critical role in the etiopathogenesis of chronic tendinopathy. Melatonin is an endogenous molecule that exhibits antioxidant and anti-inflammatory activity. The aim of... -
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- Therapeutic Effect of Fimasartan in a Rat Model of Myocardial Infarction Evaluated by Cardiac Positron Emission Tomography with [¹â¸F]FPTP
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Park H, Kim HS, Hong YJ, Min JJ, Kim HB, Kim MC, Sim DS, Kim JH, Kim DY, Lee JS, Ahn Y, Jeong MH
- KMID: 2447213
- Chonnam Med J.
- 2019 May;55(2):109-115.
- doi: 10.4068/cmj.2019.55.2.109
We evaluated the efficacy of fimasartan on perfusion defects and infarction size in an animal model of myocardial infarction (MI), with echocardiography and positron emission tomography (PET) using a ¹â¸F-labeled... -
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- Effect of sec-O-glucosylhamaudol on mechanical allodynia in a rat model of postoperative pain
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Koh GH, Song H, Kim SH, Yoon MH, Lim KJ, Oh SH, Jung KT
- KMID: 2449821
- Korean J Pain.
- 2019 Apr;32(2):87-96.
- doi: 10.3344/kjp.2019.32.2.87
BACKGROUND: This study was performed in order to examine the effect of intrathecal sec-O-glucosylhamaudol (SOG), an extract from the root of the Peucedanum japonicum Thunb., on incisional pain in a... -
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