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Establishment of External Quality Assessment Material Preparation Method for Next-Generation Sequencing-Based Liquid Biopsy Scheme

Hong J, Yu J, Gu H, Lee J, Lee W, Chun S, Min WK

Background: Next-generation sequencing (NGS)-based liquid biopsy testing using peripheral blood is a minimally invasive technique that can identify the characteristics of tumor-derived circulating tumor DNA (ctDNA) in cellfree DNA (cfDNA)....
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Commutability Assessment of Frozen Human Serum Pools for External Quality Assessment of Tumor Markers

Cho Ej, Kim SH, Hong J, Lee H, Hyun J, Cho SE, Lee W, Kim HS, Oh EJ, Chun S, Min WK

Background: Commutability is essential to harmonize different measuring systems and to evaluate the performance of participating laboratories in external quality assessment (EQA). This study aims to assess the com mutability...
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Spontaneous Rib Fracture during Boston Brace Treatment for Adolescent Idiopathic Scoliosis

Park EJ, Min WK, Chung S

Brace treatment is a well-documented conservative treatment method for adolescent idiopathic scoliosis. On the other hand, previous studies reported skin problems, decreased lung capacity, and chest wall deformity as complications....
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Investigation to Reduce Delivery Delay Rate of Proficiency Test Materials and Maintaining Materials in Proper Temperature Ranges during Delivery

Ahn S, Oh Y, Chun S, Min WK

Background: The Korean Association of External Quality Assessment Service provides proficiency test (PT) materials through a logistics company. We investigated the delivery times of PT materials in 2020 and the...
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Recent Trends in Creatinine Assays in Korea: LongTerm Accuracy-Based Proficiency Testing Survey Data by the Korean Association of External Quality Assessment Service (2011–2019)

Jeong TD, Cho EJ, Lee K, Lee W, Yun YM, Chun S, Song J, Min WK

Background: Accurate serum creatinine (Cr) concentration measurement is essential for evaluating kidney function. In 2011, the Korean Association of External Quality Assessment Service (KEQAS) launched an accuracy-based Cr proficiency testing...
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Standardization Status of Total Cholesterol Concentration Measurement: Analysis of Korean External Quality Assessment Data

Yoon YA, Lee YW, Kim S, Lee K, Park HD, Chun S, Min WK

Background: Total cholesterol concentration measurement is important in the diagnosis of dyslipidemia and evaluation of cardiovascular disease risk factors. Measurement reliability for obtaining an accurate total cholesterol concentration requires procedure...
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Development of a Method for Manufacturing External Quality Assessment Material for Genetic Testing of Solid Tumors Using Mutant and Wild-Type Cell Lines

Hong J, Kim JH, Park S, Lee SG, Lee W, Chun S, Min WK

Background: DNA extracted from mutant cell lines is frequently used as an external quality assessment (EQA) material for genetic testing of solid tumors because it is easy to obtain. However,...
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Schemes and Performance Evaluation Criteria of Korean Association of External Quality Assessment (KEQAS) for Improving Laboratory Testing

Kim S, Lee K, Park HD, Lee YW, Chun S, Min WK

External quality assessment (EQA) is important for evaluating clinical laboratories and enhancing their testing quality. EQA schemes are variable; thus, it is crucial that the EQA organizers share their experiences...
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A Novel Splice Variant (c.438T>A) of APC, Suspected by Family History and Confirmed by RNA Sequencing

Lee H, Kim HK, Yang DH, Hong YS, Lee W, Lim SB, Byeon JS, Chun S, Min WK

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Clinical Outcomes of Cervical Transforaminal Epidural Block Using Local Anesthetics with or without a Steroid for Cervical Spondylotic Radiculopathy

Park EJ, Kim SM, Chung S, Min WK

Objectives: To evaluate and compare the clinical outcomes of cervical transforaminal epidural block (CTEB) using local anesthetics with or without a steroid for cervical spondylotic radiculopathy (CSR). Summary of Literature Review:...
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Identification of a Novel Splice Variant (c.423-8A>G) of APC by RNA Sequencing

Kim A, Kim HK, Ahn S, Hong YS, Lim SB, Byeon JS, Chun S, Min WK, Lee W

No abstract available.
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Development of an Operational Plan for the Liquid Biopsy External Quality Assessment Program in Korea

Ahn S, Kim HK, Kim JH, Lee W, Chun S, Lee WG, Min WK

Background: Liquid biopsy is a useful assay for the diagnosis, treatment, and prognosis prediction of solid tumors and its clinical application is expanding. Therefore, the need for developing an External...
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A Case of Lynch Syndrome with the Deletion of Multiple Exons of the MLH1 Gene, Detected by Next-Generation Sequencing

Hong J, Kim H, Hong YS, Lee W, Lim SB, Byeon JS, Chun S, Min WK

A 26-year-old man underwent colonoscopy to investigate weight loss and a lesion suspicious of colorectal cancer was detected. He had a family history of colorectal cancer and hepatocellular carcinoma. The...
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Performance Evaluation of the Total Prostate- Specific Antigen (PSA), Free PSA, and [–2]proPSA Assay for Calculation of the Prostate Health Index Using the UniCel DxI 800 Analyzer

Choi WK, Kim HK, Lee W, Chun S, Min WK

BACKGROUND: Prostate-specific antigen (PSA) is widely used as a tumor marker of prostate cancer, but it is not specific for cancer. Numerous efforts have been made to find another tumor...
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Current Status of Estimated Glomerular Filtration Rate Reporting in Korea

Kim SK, Jeong TD, Park S, Lee YW, Min WK

BACKGROUND: We aimed to investigate the current status of estimated glomerular filtration rate (eGFR) reporting in clinical laboratories for the first time in Korea. METHODS: The eGFR proficiency testing data obtained...
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Clinical Efficacy of Cages in Anterior Cervical Fusion for Degenerative Cervical Disease

Park MS, Min WK, Ko SB, Kim YY, Choi BW, Ko JH

STUDY DESIGN: Review of the literature. OBJECTIVES: To present up-to-date information on the use of cages in anterior cervical fusion for degenerative cervical disease. SUMMARY OF LITERATURE REVIEW: The use of cages...
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Comparison of Magnetic Resonance Imaging and Operation Waiting Times in Patients Having Traumatic Cervical Spinal Cord Injury; with or without Bony Lesions

Heo J, Min WK, Oh CW, Kim JW, Park KH, Seo I, Park EK

PURPOSE: To compare the time intervals to magnetic resonance imaging (MRI) and surgical treatment in patients having traumatic cervical spinal cord injury (SCI) with and without bony lesions. METHODS: Retrospectively analyzed...
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Analytical and Clinical Performance of the Nanopia Krebs von den Lungen 6 Assay in Korean Patients With Interstitial Lung Diseases

Cho EJ, Park KJ, Ko DH, Koo HJ, Lee SM, Song JW, Lee W, Lee HK, Do KH, Chun S, Min WK

BACKGROUND: Krebs von den Lungen 6 (KL-6) is a sensitive marker for diagnosing, monitoring, and predicting the prognoses of interstitial lung diseases (ILDs). This study aimed to evaluate the performance...
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Essential Elements for Establishing Clinical Next-generation Sequencing Testing

Park KJ, Lee W, Chun S, Min WK

Over the past decade, next-generation sequencing (NGS) has evolved at an astonishing pace and has revolutionized clinical medicine as well as genomics research. The rapid advancements in NGS technologies have...
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Performance Evaluation of the Stat Profile pHOx Ultra Blood Gas Analyzer

Lee HY, Ahn S, Kim HK, Lee W, Chun S, Min WK

The objective of this study was to evaluate the analytical performance of the Stat Profile pHOx Ultra Blood Gas Analyzer (Nova Biomedical, USA), a new blood gas/chemistry analyser, including its...
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