- Expression of Heat Shock Protein 70 Modulates the Chemoresponsiveness of Pancreatic Cancer
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Hyun JJ, Lee HS, Keum B, Seo YS, Jeen YT, Chun HJ, Um SH, Kim CD
- KMID: 1712336
- Gut Liver.
- 2013 Nov;7(6):739-746.
BACKGROUND/AIMS: Heat shock protein (HSP) 70 is constitutively overexpressed in pancreatic cancer cells (PCCs) and appears to confer protection against chemotherapeutics. We investigated whether modulating HSP 70 increases chemoresponsiveness to... -
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- Mutation and expression of the p27KIP1 and p57KIP2 genes in human gastric cancer
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Shin JY, Kim HS, Lee KS, Kim JB, Park JB, Won MH, Chae SW, Choi YH, Choi KC, Park YE, Lee JY
- KMID: 1109306
- Exp Mol Med.
- 2000 Jun;32(2):79-83.
Cyclin-dependent kinase inhibitors (CDKI) are negative regulators of cell cycle progression by binding the cyclin-CDK complex and inhibiting the CDK activity. Genetic alteration in the CDKI genes has been implicated... -
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- Histamine and spontaneously released mast cell granules ffect the cell growth of human hepatocellular carcinoma cells
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Lampiasi N, Azzolina A, Montalto G, Cervello M
- KMID: 1047079
- Exp Mol Med.
- 2007 Jun;39(3):284-294.
The role of mast cells in tumor growth is still controversial. In this study we analyzed the effects of both histamine and pre-formed mediators spontaneously released by mast cells on... -
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- Cell proliferation and neuroblast differentiation in the dentate gyrus of high-fat diet-fed mice are increased after rosiglitazone treatment
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Yoo DY, Kim W, Kim DW, Nam SM, Jung HY, Kim JW, Lee CH, Choi JH, Won MH, Yoon YS, Hwang IK
- KMID: 1737607
- J Vet Sci.
- 2014 Mar;15(1):27-33.
- doi: 10.4142/jvs.2014.15.1.27
In this study, we determined how rosiglitazone (RSG) differentially affected hippocampal neurogenesis in mice fed a low-fat diet (LFD) or high-fat diet (HFD; 60% fat). LFD and HFD were given... -
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- Fast neutron irradiation deteriorates hippocampus-related memory ability in adult mice
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Yang M, Kim H, Kim J, Kim SH, Kim JC, Bae CS, Kim JS, Shin T, Moon C
- KMID: 1364996
- J Vet Sci.
- 2012 Mar;13(1):1-6.
- doi: 10.4142/jvs.2012.13.1.1
Object recognition memory and contextual fear conditioning task performance in adult C57BL/6 mice exposed to cranial fast neutron irradiation (0.8 Gy) were examined to evaluate hippocampus-related behavioral dysfunction following acute... -
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