- Select Macrophage Noncoding RNAs of Interest in Cardiovascular Disease
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Enchill Z, Lantz C, Thorp EB
- KMID: 2470807
- J Lipid Atheroscler.
- 2020 Jan;9(1):153-161.
- doi: 10.12997/jla.2020.9.1.153
Cardiovascular disease remains a leading cause of morbidity and mortality worldwide. Aspects of disease severity that are associated with heightened inflammation, such as during atherosclerosis or after myocardial infarction, are... -
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- Differential Activation of Macrophages Based on Their Environment in Advanced Age
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Lee DY, Lim JS, Cho KA
- KMID: 2468141
- Chonnam Med J.
- 2020 Jan;56(1):12-19.
- doi: 10.4068/cmj.2020.56.1.12
The macrophage displays functional and phenotypic diversity, which appears, in no small part, to stem from the ability of macrophages to adapt functionally to changes in their tissue microenvironment. Here,... -
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- Polymorphism in Macrophage Migration Inhibitory Factor -173GC in Pediatric Patients with Autoimmune Hepatitis
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Alsayed MA, Elbeah SM, El-Desoky , Elziny SM, Megahed A
- KMID: 2467894
- Pediatr Gastroenterol Hepatol Nutr.
- 2020 Jan;23(1):63-71.
- doi: 10.5223/pghn.2020.23.1.63
PURPOSE: Autoimmune hepatitis (AIH) is a chronic disease that may lead to cirrhosis. The immunopathogenesis of AIH is not fully understood and it mainly involves T-cell mediated mechanism. Macrophage migration... -
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- Macrophages in xenotransplantation
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Kim JY
- KMID: 2468157
- Korean J Transplant.
- 2019 Dec;33(4):74-82.
- doi: 10.4285/jkstn.2019.33.4.74
Xenotransplantation refers to organ transplantation across species. Immune rejection of xenografts is stronger and faster than that of allografts because of significant molecular differences between species. Recent studies have revealed... -
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- PD-1: A Negative Regulator of Phagocytosis by Tumour-Associated Macrophages in Colon Cancer
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Islam Tultul MS, Koh YS
- KMID: 2468029
- J Bacteriol Virol.
- 2019 Dec;49(4):230-236.
- doi: 10.4167/jbv.2019.49.4.230
Programmed cell death protein 1 (PD-1) is an immuno-inhibitory cell surface receptor protein of the myeloid, and lymphoid cell. PD-L1 is the ligand of PD-1, which is abundant in different... -
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- Aralia cordata Extract Activates NF-κB and MAPK Signaling Pathways and Induces Pro-inflammatory Changes in RAW264.7 Macrophages
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Seo DW, Cho YI, Yi YJ, Lee SM
- KMID: 2468022
- J Bacteriol Virol.
- 2019 Dec;49(4):153-161.
- doi: 10.4167/jbv.2019.49.4.153
Macrophages play essential roles in innate immune responses by producing various immune mediators. Therefore, modulating macrophage function is an attractive strategy to treat immune disorders. Aralia cordata var. continentalis (AC),... -
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- An Important Role of Macrophages for Wound Margin Regeneration in a Murine Flap Model
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Won HR, Seo C, Lee HY, Roh J, Kim CH, Jang JY, Shin YS
- KMID: 2467058
- Tissue Eng Regen Med.
- 2019 Dec;16(6):667-674.
- doi: 10.1007/s13770-019-00214-x
BACKGROUND: Macrophages have been known to have diverse roles either after tissue damage or during the wound healing process; however, their roles in flap wound healing are poorly understood. In... -
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- Perivascular Stem Cells Suppress Inflammasome Activation during Inflammatory Responses in Macrophages
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Kim J, Kim WJ, Ha KS, Han ET, Park WS, Yang SR, Hong SH
- KMID: 2465882
- Int J Stem Cells.
- 2019 Nov;12(3):419-429.
- doi: 10.15283/ijsc19115
BACKGROUND AND OBJECTIVES: Perivascular stem cells (PVCs) have been identified as precursors of mesenchymal stem cells (MSCs) that offer promising prospects for application in the development of cellular therapies. Although... -
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- Rhodanthpyrone A and B play an anti-inflammatory role by suppressing the nuclear factor-κB pathway in macrophages
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Kim KS, Han CY, Han YT, Bae EJ
- KMID: 2461042
- Korean J Physiol Pharmacol.
- 2019 Nov;23(6):493-499.
- doi: 10.4196/kjpp.2019.23.6.493
Macrophage-associated inflammation is crucial for the pathogenesis of diverse diseases including metabolic disorders. Rhodanthpyrone (Rho) is an active component of Gentiana rhodantha, which has been used in traditional Chinese medicine... -
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- Ubiquitin E3 Ligase Pellino-1 Inhibits IL-10-mediated M2c Polarization of Macrophages, Thereby Suppressing Tumor Growth
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Kim D, Koh J, Ko JS, Kim HY, Lee H, Chung DH
- KMID: 2461196
- Immune Netw.
- 2019 Oct;19(5):e32.
- doi: 10.4110/in.2019.19.e32
Pellino-1 is a ubiquitin (Ub) E3 ligase that plays a role in M1, but not M2a polarization of macrophages. However, it is unknown whether Pellino-1 regulates IL-10-mediated M2c polarization of... -
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- PF-04620110, a Potent Antidiabetic Agent, Suppresses Fatty Acid-Induced NLRP3 Inflammasome Activation in Macrophages
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Jo SI, Bae JH, Kim SJ, Lee JM, Jeong JH, Moon JS
- KMID: 2460961
- Diabetes Metab J.
- 2019 Oct;43(5):683-699.
- doi: 10.4093/dmj.2019.0112
BACKGROUND: Chronic inflammation has been linked to insulin resistance and type 2 diabetes mellitus (T2DM). High-fat diet (HFD)-derived fatty acid is associated with the activation of chronic inflammation in T2DM.... -
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- Low-Frequency Intermittent Hypoxia Suppresses Subcutaneous Adipogenesis and Induces Macrophage Polarization in Lean Mice
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Wang Y, Lee MY, Mak JC, Ip MS
- KMID: 2460959
- Diabetes Metab J.
- 2019 Oct;43(5):659-674.
- doi: 10.4093/dmj.2018.0196
BACKGROUND: The relationship between obstructive sleep apnoea (OSA) and metabolic disorders is complex and highly associated. The impairment of adipogenic capacity in pre-adipocytes may promote adipocyte hypertrophy and increase the... -
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- Interaction between Brucella melitensis 16M and small ubiquitin-related modifier 1 and E2 conjugating enzyme 9 in mouse RAW264.7 macrophages
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Yi J, Wang Y, Li Q, Zhang H, Shao Z, Deng X, He J, Xiao C, Wang Z, Wang Y, Chen C
- KMID: 2464100
- J Vet Sci.
- 2019 Sep;20(5):e54.
- doi: 10.4142/jvs.2019.20.e54
Brucella is an intracellular pathogen that invades a host and settles in its immune cells; however, the mechanism of its intracellular survival is unclear. Modification of small ubiquitin-related modifier (SUMO)... -
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- Piperlongumine suppressed osteoclastogenesis in RAW264.7 macrophages
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Jin SM, Kang HM, Park DB, Yu SB, Kim IR, Park BS
- KMID: 2460804
- Int J Oral Biol.
- 2019 Sep;44(3):89-95.
- doi: 10.11620/IJOB.2019.44.3.89
Piperlongumine (PL) is a natural product found in long pepper (Piper longum). The pharmacological effects of PL are well known, and it has been used for pain, hepatoprotection, and asthma... -
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- Pro-Inflammatory Role of S1P₃ in Macrophages
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Heo JY, Im DS
- KMID: 2455092
- Biomol Ther.
- 2019 Jul;27(4):373-380.
- doi: 10.4062/biomolther.2018.215
Sphingosine kinase 1 and its product, sphingosine 1-phosphate (S1P), as well as their receptors, have been implicated in inflammatory responses. The functions of receptors S1Pâ‚ and S1Pâ‚‚ on cell motility... -
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- Inflammatory Effect of Light-Emitting Diodes Curing Light Irradiation on Raw264.7 Macrophage
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Jeong MJ, Kil KS, Lee MH, Lee SY, Lee HJ, Lim DS, Jeong SJ
- KMID: 2451791
- J Dent Hyg Sci.
- 2019 Jun;19(2):133-140.
- doi: 10.17135/jdhs.2019.19.2.133
BACKGROUND: The light-emitting diode (LED) curing light used is presumed to be safe. However, the scientific basis for this is unclear, and the safety of LED curing light is still... -
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- Short-chain Fatty Acids Inhibit Staphylococcal Lipoprotein-induced Nitric Oxide Production in Murine Macrophages
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Park JW, Kim HY, Kim MG, Jeong S, Yun CH, Han SH
- KMID: 2444157
- Immune Netw.
- 2019 Apr;19(2):e9.
- doi: 10.4110/in.2019.19.e9
Staphylococcus aureus, a Gram-positive pathogen, can cause severe inflammation in humans, leading to various life-threatening diseases. The lipoprotein is a major virulence factor in S. aureus-induced infectious diseases and is... -
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- Effector Pathways of Toll-like Receptor-inducible Innate Immune Responses in Macrophages
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Jo EK, Suh HW, Park JK
- KMID: 2442584
- J Bacteriol Virol.
- 2019 Mar;49(1):12-26.
- doi: 10.4167/jbv.2019.49.1.12
Toll-like receptors (TLR) are well-characterized pattern recognition receptors that can recognize and respond to diverse pathogen-associated or danger-associated molecular patterns during infection. TLR signaling in macrophages triggers in the intracellular... -
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- Tumor-Associated Macrophages as Potential Prognostic Biomarkers of Invasive Breast Cancer
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Jeong H, Hwang I, Kang SH, Shin HC, Kwon SY
- KMID: 2441850
- J Breast Cancer.
- 2019 Mar;22(1):38-51.
- doi: 10.4048/jbc.2019.22.e5
PURPOSE: Tumor-associated macrophages (TAMs) are activated macrophages associated with tumor progression in various cancers. TAMs can polarize M1 or M2 type. M1 has a pro-inflammatory function and kills pathogens. Conversely,... -
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- Plasma Macrophage Migration Inhibitory Factor and CCL3 as Potential Biomarkers for Distinguishing Patients with Nasopharyngeal Carcinoma from High-Risk Individuals Who Have Positive Epstein-Barr Virus Capsid Antigen-Specific IgA
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Xue N, Lin JH, Xing S, Liu D, Li SB, Lai YZ, Wang XP, Mao MJ, Zhong Q, Zeng MS, Liu WL
- KMID: 2437628
- Cancer Res Treat.
- 2019 Jan;51(1):378-390.
- doi: 10.4143/crt.2018.070
PURPOSE: The purpose of this study was to identify novel plasma biomarkers for distinguishing nasopharyngeal carcinoma (NPC) patients from healthy individuals who have positive Epstein-Barr virus (EBV) viral capsid antigen... -
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