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Comparison of Macrophage Activation and Tumor - cytotoxicity in Mouse and hamster Peritoneal Macrophages by Cold Stress

Jung NP, Choi IH, Oh YK, Shin HC, Jeon HK, Gwag BJ

  • KMID: 1548375
  • Korean J Immunol.
  • 1997 Dec;19(4):505-512.
No abstract available.
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Macrophage Activation Syndrome as the Extreme Form of Kawasaki Disease

Park HJ, Cho YJ, Bae EY, Choi UY, Lee SY, Jeong DC, Lee KY, Kang JH

  • KMID: 2072435
  • Korean J Pediatr Infect Dis.
  • 2010 Dec;17(2):177-181.
Few cases of macrophage activation syndrome (MAS) or reactive hemophagocytic lymphohistiocytosis (HLH) during the acute febrile phase of Kawasaki disease (KD) have been reported. We report on a case of...
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A Case of Macrophage Activation Syndrome Developed in Female Adolescent with Systemic Lupus Erythematosus

Keum SW, Kim MJ, Bae EY, Han SB, Chung NG, Jeong DC, Kang JH

Macrophage activation syndrome (MAS) is a severe complication in patients with autoimmune disease. We should consider MAS in patients with autoimmune disease, who present with newly developed fever, and MAS...
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Select Macrophage Noncoding RNAs of Interest in Cardiovascular Disease

Enchill Z, Lantz C, Thorp EB

Cardiovascular disease remains a leading cause of morbidity and mortality worldwide. Aspects of disease severity that are associated with heightened inflammation, such as during atherosclerosis or after myocardial infarction, are...
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DICAM Inhibits Activation of Macrophage by Lipopolysaccharide

Jung YK, Park HR, Lee EJ, Jeong DH, Kim GW, Choi JY, Han SW

OBJECTIVE: DICAM, a dual Ig domain containing adhesion molecule, is involved in cell-cell adhesion through direct interaction with alphavbeta3 integrin. In our previous study showing the inhibitory role of DICAM...
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Tocilizumab-induced Transaminitis in a Seropositive Rheumatoid Arthritis Patient with Macrophage Activation Syndrome

Yoo BW, Park CK, Yun HR, Kim D, Lee SK, Lee SW

As a new humanized monoclonal antibody against the interleukin-6 receptor, tocilizumab is currently used for the treatment of rheumatoid arthritis (RA) patients. Tocilizumab was reported to provoke drug-related liver toxicity,...
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Effect of Fibronectin to Macrophage for Destruction of MBT-2 Cell

Seo IY, Rim JS, Chung HT

  • KMID: 1913780
  • Korean J Urol.
  • 1996 Jan;37(1):1-7.
Fibronectin(Fn) is a large, multidomain glycoprotein, which exists in a soluble form in plasma and an insoluble fibrillar form in extracellular matrices. Fn affects many aspects of cellular responses. However,...
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Immunohistochemical Study on the Effect of Dexamethasone on the Luteolysis of Corpus Luteum of the Rat

Park SH, Ko YB, Rhee YE, Noh HT, Kim WS

  • KMID: 1483349
  • Korean J Reprod Med.
  • 2008 Mar;35(1):61-67.
OBJECTIVE: This study was attempted to look at the effect of dexamethasone on the luteolysis of corpus luteum in rats by immunohistochemical study. METHODS: Counting with an optical microscope was conducted...
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Refractory Macrophage Activation Syndrome in a Patient with Systemic Lupus Erythematosus Treated with Tocilizumab

Oh JS, Park J, Lee NK, Bae SH, Kim YG, Lee CK, Yoo B

Macrophage activation syndrome (MAS) is a secondary hemophagocytic lymphohistiocytosis caused by autoimmune diseases, such as systemic lupus erythematosus (SLE). It is characterized by fever, cytopenia, coagulopathy, hepatosplenomegaly, elevated liver enzyme,...
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Macrophage Activation Syndrome in Juvenile Rheumatoid Arthritis Successfully Treated with Cyclosporine A: A Case Report

You CR, Kim HR, Yoon CH, Lee SH, Park SH, Kim HY

Macrophage activation syndrome (MAS) is one of the serious complications of juvenile rheumatoid arthritis (JRA) and recently, cyclosporine A has been found to be effective in patients with corticosteroid-resistant MAS....
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A Case of Macropharge Activation Syndrome Successfully Treated with Combination Therapy Including Etanercept

Sim YS, Kim HS, Kim KN

Macrophage activation syndrome (MAS) is a severe, potentially life-threatening complication of childhood systemic inflammatory disorder, primarily systemic onset juvenile rheumatoid arthritis (SoJRA). It is characterized by pancytopenia, liver insufficiency, coagulopathy,...
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Phosphatidylinositol-3-kinase Inhibitor Enhances Nitric Oxide Synthesis and Apoptosis in LPS-Stimulated Macrophages

Park YC

  • KMID: 1610767
  • Korean J Anat.
  • 2003 Aug;36(4):323-329.
Phosphatidylinositol-3-kinase (PI3-kinase) is critical player in cell proliferation and death. The mechanism by which bacterial lipopolysaccharide (LPS) induces synthesis of nitric oxide (NO) in murine macrophages is incompletely understood. In...
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Effect of Caffeic Acid Phenethyl Ester on Lipopolysaccharide-induced Murine Macrophage Activation

Lee SH, Li M, Lee DW, Lim DY, Jeong CW, Kwak SH

BACKGROUND: Caffeic acid phenethyl ester (CAPE) is an active component of propolis and is known to have anti-inflammatory properties. This study was performed to evaluate the effects of CAPE on...
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Macrophage Activation Syndrome Triggered by Herpes Viral Infection as the Presenting Manifestation of Juvenile Systemic Lupus Erythematosus

Noh JH, Jeong DY, Jeon IS, Kim HM

Macrophage activation syndrome (MAS) is a rare complication in systemic lupus erythematosus (SLE) that can be triggered by infections. Due to the fact that MAS may mimic clinical features of...
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Cell Motility Is Decreased in Macrophages Activated by Cancer Cell-Conditioned Medium

Go A, Ryu YK, Lee JW, Moon EY

  • KMID: 2170667
  • Biomol Ther.
  • 2013 Nov;21(6):481-486.
Macrophages play a role in innate immune responses to various foreign antigens. Many products from primary tumors influence the activation and transmigration of macrophages. Here, we investigated a migration of...
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Selective M1 macrophage polarization in granuloma-positive and granuloma-negative Crohn's disease, in comparison to intestinal tuberculosis

Das P, Rampal R, Udinia S, Kumar T, Pilli S, Wari N, Ahmed IK, Kedia S, Gupta SD, Kumar D, Ahuja V

BACKGROUND/AIMS: Classical M1 macrophage activation exhibits an inflammatory phenotype while alternative M2 macrophage activation exhibits an anti-inflammatory phenotype. We aimed to determine whether there are discriminant patterns of macrophage polarization...
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Characterization and Immunopotentiating Effects of the Glycoprotein Isolated from Dioscorea Batatas

Huong PT, Lee CH, Li MH, Lee MY, Kim JK, Lee SM, Seon JH, Lee DC, Jeon YJ

We demonstrate that glycoprotein isolated from Dioscorea batatas (GDB) has immunostimulatory effects including macrophage activation. Analysis of infiltration of inflammatory cells into peritoneal cavity showed GDB treatment significantly increased the...
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Activation of Macrophage by Polysaccharide Isolated from Salicornia herbacea L.

Im JS, Lee SK, Chang IY, Ha HC, Lim Y, Kim HY, Park KH, Yoon SP

  • KMID: 1512979
  • Korean J Phys Anthropol.
  • 2006 Jun;19(2):117-124.
Salicornia herbacea L. is one of the halophytes that can grow in salt marshes, or salt fields along the seashores in Korea. The objective of this study is to investigate...
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Macrophage Activation Syndrome in a Child with Systemic Juvenile Rheumatoid Arthritis

Hur M, Kim YC, Lee KM, Kim KN

Macrophage activation syndrome (MAS) is a rare and potentially fatal complication of rheumatic disorders in children. We describe a 13-month-old boy in whom MAS developed as a complication of systemic...
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Effect of Nitric Oxide on ADP-ribose Pyrophosphatase Activity

Kim JH

BACKGROUND: ADP-ribosyl pyrophosphatases (ADPRase) has been known to catalyze the hydrolysis of ADP-ribose to ribose-5-phosphate and AMP. The role of ADPRase has been suggested to sanitize the cell by removing...
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