J Rheum Dis.  2014 Apr;21(2):96-100. 10.4078/jrd.2014.21.2.96.

A Case of Macrophage Activation Syndrome Developed in Female Adolescent with Systemic Lupus Erythematosus

• Keum SW
• Kim MJ
• Bae EY
• Han SB
• Chung NG
• Jeong DC
• Kang JH

• KMID: 2094665
• DOI: http://doi.org/10.4078/jrd.2014.21.2.96

Abstract

Macrophage activation syndrome (MAS) is a severe complication in patients with autoimmune disease. We should consider MAS in patients with autoimmune disease, who present with newly developed fever, and MAS needs proper management due to grave outcome. We report a case of MAS in a 15-year-old adolescent girl, who was newly diagnosed with systemic lupus erythematosus 1 month before the diagnosis of MAS. Her MAS was improved by intensive treatment, including etoposide.

Keyword

Macrophage activation syndrome; Systemic lupus erythematosus; Adolescent

MeSH Terms

Adolescent*
Autoimmune Diseases
Diagnosis
Etoposide
Female
Fever
Humans
Lupus Erythematosus, Systemic*
Macrophage Activation Syndrome*
Etoposide

Figure

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  Figure 1. Clinical course of an adolescent girl diagnosed with macrophage activation syndrome developed in systemic lupus erythematosus.

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