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Absence of esophageal eosinophilia in a toddler with severe eosinophilic esophagitis

Loh W, Wright KM, Chiou FK

Eosinophilic esophagitis (EoE) is a clinicopathologic disease characterised by esophageal dysfunction and eosinophil-predominant inflammation. Diagnosing EoE in children is particularly challenging as they tend to present with nonspecific symptoms and...
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Tolerance to etoricoxib in children with nonsteroidal anti-inflammatory drug hypersensitivity

Loh W, Lim HH, Rao R, Goh A, Ong LX, Chiang WC

BACKGROUND: Cyclooxygenase-2 (COX-2) inhibitors have been found to be safe alternatives in adults with cross-intolerant hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs). However they are usually not prescribed in children and...
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Goat's milk anaphylaxis in a cow's milk tolerant child

Goh SH, Chong KW, Loh W, Goh AE

Goat's milk (GM) allergy commonly occurs together with cow's milk (CM) allergy due to cross-reactivity between highly homologous proteins. We present an unusual case of GM anaphylaxis in a CM...
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Pilot study of the use of Yin Qiao San in children with conventional antipyretic hypersensitivity

Liew WK, Loh W, Chiang WC, Goh A, Chay OM, Iancovici Kidon M

BACKGROUND: Children with a diagnosis of cross-reactive hypersensitivity to both paracetamol and nonsteroidal anti-inflammatory drugs are limited in their choice of antipyretics. OBJECTIVE: The aim of this pilot study is to...
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Cashew nut allergy in Singaporean children

Chitta S, Lian BX, Rao R, Loh W, Goh A, Chong KW

BACKGROUND: There has been an increasing trend of nut allergies in Singapore. OBJECTIVE: The aim of this study was to review the clinical characteristics of children with cashew nut allergy. METHODS: A...
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An unusual case of infant seizures with anaphylaxis to wheat

Chong KW, Ling S, Loh W

Wheat allergy is one of the commonest food allergies in childhood and it typically presents with IgE mediated reactions, including anaphylaxis. Seizures are not typically reported to be a direct...
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A 5-year retrospective review of children with peanut allergy in the largest paediatric hospital in Singapore

Lee MP, Saffari SE, Loh W, Goh SH, Goh A, Chiang WC, Chong KW

BACKGROUND: The prevalence of peanut allergy (PA) among children has increased significantly over the past decade. Even though the prevalence of PA in Singapore is considered low, peanut is the...
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Predictive value of peanut skin prick test, specific IgE in peanut-sensitized children in Singapore

Chong KW, Saffari SE, Chan N, Seah R, Tan CH, Goh SH, Goh A, Loh W

BACKGROUND: The predictive decision points for both peanut skin prick test (SPT) wheal size and serum IgE concentrations, in peanut-sensitized children, have not been evaluated in Singapore. OBJECTIVE: We aim to...
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