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The role of roxadustat in chronic kidney disease patients complicated with anemia

Liu J, Yang F, Waheed Y, Li S, Liu K, Zhou X

The incidence of chronic kidney disease (CKD) is increasing worldwide and the current prevalence rate is 13.4%. There are > 120 million CKD patients in China and this number is...
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Dipeptidyl peptidase-4 inhibitors are associated with improved survival of patients with diabetes mellitus and hepatocellular carcinoma receiving immunotherapy: Letter to the editor on “Statin and aspirin for chemoprevention of hepatocellular carcinoma: Time to use or wait further?”

Yiu DCY, Lin H, Wong VWS, Wong GLH, Liu K, Yip TCF

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Transcriptome Sequencing Reveals the Potential Mechanisms of Modified Electroconvulsive Therapy in Schizophrenia

Peng W, Tan Q, Yu M, Wang P, Wang T, Yuan J, Liu D, Chen D, Huang C, Tan Y, Liu K, Xiang B, Liang X

Objective Schizophrenia (SCZ) is one of the most common and severe mental disorders. Modified electroconvulsive therapy (MECT) is the most effective therapy for all kinds of SCZ, and the underlying...
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A retrospective study on the efficacy of Roxadustat in peritoneal dialysis patients with erythropoietin hyporesponsiveness

Liu J, Li S, Yang F, Li T, Li R, Waheed Y, Meng C, Li S, Liu K, Tong Y, Xu H, Tian C, Zhou X

Background/Aims: Roxadustat, an oral medication for treating renal anemia, is a hypoxia-inducible factor prolyl hydroxylase inhibitor used for regulating iron metabolism and promoting erythropoiesis. To investigate the efficacy and safety...
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Phosphodiesterase Type 5 Inhibitors and Risk of Skin Cancers in Men: A Meta-Analysis and Trial Sequential Analysis Involving 7,479,852 Subjects

Lu YP, Fan S, Liang Z, Song Y, Liu K, Zhou K, Wang X, Kang J, Yang Y, Liu X

Purpose: We conducted a systematic review and meta-analysis to quantify the association between phosphodiesterase type 5 inhibitors (PDE5Is) use and skin cancers and we also examined whether down-expression of the...
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Relaxin-2 Prevents Erectile Dysfunction by Cavernous Nerve, Endothelial and Histopathological Protection Effects in Rats with Bilateral Cavernous Nerve Injury

Liu K, Sun T, Xu W, Song J, Chen Y, Ruan Y, Li H, Cui K, Zhang Y, Feng Y, Pan J, Liang E, Xin Z, Wang T, Wang S, Liu J, Luan Y

Purpose Cavernous nerve injury induced erectile dysfunction (ED) is a refractory complication with high incidence in person under radical prostatectomy. Studies have shown that relaxin-2 (RLX-2) plays a vital role of...
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Reduction of Lower Cervical Facet Dislocation: A Review of All Techniques

Liu K, Zhang Z

Objective: The surgical treatment of lower cervical facet dislocation is controversial. Great advancements on reduction techniques for lower cervical facet dislocation have been made in the past decades. However, there...
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The Role of Gut Microbiota and Genetic Susceptibility in the Pathogenesis of Pancreatitis

Xu F, Yang C, Tang M, Wang M, Cheng Z, Chen D, Chen X, Liu K

Pancreatitis is one of the most common inflammatory diseases of the pancreas caused by autodigestion induced by excessive premature protease activation. However, recognition of novel pathophysiological mechanisms remains a still...
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Post-anesthesia care unit delirium in children with moyamoya disease undergoing indirect revascularization: incidence and risk factors

Liu K, He L

Background: Delirium in the post-anesthesia care unit (PACU) may be associated with worse outcomes in children with moyamoya disease (MMD). This retrospective study aimed to describe the prevalence of PACU...
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Ex vivo cholangioscopy in liver grafts: a novel technique to assess the biliary tree during organ preservation and machine perfusion: a experimental non-clinical study

Ly M, Lau NS, Huang J, Ly H, Ewenson K, Mestrovic N, Yousif P, Liu K, Majumdar A, McCaughan G, Crawford M, Pulitano C

Background/Aims: Biliary complications are a leading cause of morbidity after liver transplantation, but can be reduced using real-time assessment of the biliary tree. This study described a novel technique for...
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Operation start time and long-term outcome of hepatocellular carcinoma after curative hepatic resection

Lu Q, Li QS, Zhang W, Liu K, Li T, Yu JW, Lv Y, Zhang XF

Purpose: The objective of the current study was to examine the potential effects of surgery start times (morning vs. afternoon) on the long-term prognosis of patients after hepatic resection (HR)...
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Modifiable Risk Factors for Cardiovascular Disease in Korea and Japan

Arafa A, Lee HH, Eshak ES, Shirai K, Liu K, Li J, Anni NS, Shim SY, Kim HC, Iso H

Cardiovascular disease (CVD) is the leading cause of death and a major contributor to disability worldwide. Since the majority of cardiovascular events are preventable, identification of modifiable CVD risk factors...
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Association Between Skeletal Muscle Mass Indices and Cognitive Function Among Inpatients With Stable Schizophrenia

Shuai D, Wang B, Cai D, Guo Y, Lei X, Liu K, Wang Y

Objective To investigate the correlation between appendicular skeletal muscle mass (ASM)/height (ASMIht), ASM/body mass index (ASMIBMI), ASM/weight (ASMIwt), and ASM/waist circumference (ASMIwc) and cognitive function among inpatients with stable schizophrenia. Methods...
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Predicting Postoperative Progression of Ossification of the Posterior Longitudinal Ligament in the Cervical Spine Using Interpretable Radiomics Models

Qin S, Qu R, Liu K, Yan R, Zhao W, Xu J, Zhang E, Zhou F, Lang N

Objective: This study investigates the potential of radiomics to predict postoperative progression of ossification of the posterior longitudinal ligament (OPLL) after posterior cervical spine surgery. Methods: This retrospective study included 473...
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Changes in Cerebral Blood Flow in Patients Who Receive Different Durations of Hemodialysis: An Arterial Spin Labeling MRI Study

Xue Y, Wu Z, Li B, Sun G, Jia F, Liu K

Background and Purpose This study aimed to determine the changes in cerebral blood flow (CBF) in patients who received different durations of hemodialysis (HD) using arterial spin labeling magnetic resonance...
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Different Characteristics of Psychological and Sleep Symptoms Across Social Media Addiction and Internet Gaming Disorder in Chinese Adolescents- A Network Analysis

Zhang W, Jiang L, Yu M, Ma R, Wang T, Liang X, He R, Xu C, Hu S, Tan Y, Liu K, Xiang B

Objective Previous research has explored a variety of mental disorders associated with Internet Gaming Disoder (IGD) and Social Media Addiction (SMA). To date, few studies focused on the network characteristics...
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Downregulation of TET2 Contributes to Nasal Polypogenesis Through Hypoxia-Inducible Factor 1α-Mediated Epithelial-to-Mesenchymal Transition

Liu K, Xu Y

Objectives. Hypoxia-inducible factor 1α (HIF1α) and Tet methylcytosine dioxygenase 2 (TET2) have been reported to mediate nasal polypogenesis through the epithelial-to-mesenchymal transition (EMT). Additionally, HIF1α can regulate the expression and...
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The Association Between Causality Orientation and Internet Gaming Disorder, and the Role of Sensation Seeking, Anxiety, and Depression

Peng Y, Wang Y, Peng Z, Liao X, Gong K, Qin C, Tian M, Cheng X, Zhou X, Deng J, Chen Y, Feng S, Zhang M, Liu K, Xiang B, Lei W, Chen J

Objective Self-determination theory (SDT) deems that people have three causality orientations: autonomy orientation, control orientation, and impersonal orientation. Previous studies suggested that lower autonomy orientation or higher control and impersonal...
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Television Viewing Time and Breast Cancer Incidence for Japanese Premenopausal and Postmenopausal Women: The JACC Study

Cao J, Eshak ES, Liu K, Muraki I, Cui R, Iso H, Tamakoshi , JACC Study Group

PURPOSE: The evidence on effects of TV viewing time among premenopausal and postmenopausal women for breast cancer risk remains controversial and limited. MATERIALS AND METHODS: A prospective study encompassing 33,276 (17,568...
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Genetic Correlation and Mendelian Randomization Analysis Revealed an Unidirectional Causal Relationship Between Left Caudal Middle Frontal Surface Area and Cigarette Consumption

Xie H, Wang A, Yu M, Wang T, Liang X, He R, Huang C, Lei W, Chen J, Tan Y, Liu K, Xiang B

Objective Previous studies have discovered a correlation between cigarette smoking and cortical thickness and surface area, but the causal relationship remains unclear. The objective of this investigation is to scrutinize...
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