- House dust mite allergy: environment evaluation and disease prevention
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Yu SJ, Liao EC, Tsai JJ
- KMID: 2397105
- Asia Pac Allergy.
- 2014 Oct;4(4):241-252.
- doi: 10.5415/apallergy.2014.4.4.241
There are two groups of dust mites, house dust mites (HDMs) and storage mites (SMs), that have been identified in the household environment. Both could induce airway inflammation through activation... -
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- Enhanced Allergic Inflammation of Der p 2 Affected by Polymorphisms of MD-2 Promoter
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Liao EC, Hsieh CW, Chang CY, Yu SJ, Sheu ML, Wu SM, Tsai JJ
- KMID: 2147959
- Allergy Asthma Immunol Res.
- 2015 Sep;7(5):497-506.
- doi: 10.4168/aair.2015.7.5.497
PURPOSE: Myeloid differentiation-2 (MD-2) has been associated with endotoxin and inflammatory disorders because it can recognize lipopolysaccharide (LPS) binding and attenuate Toll-like receptor 4 (TLR4)-mediated signaling. However, its role in... -
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- Association of Single Nucleotide Polymorphisms in the MD-2 Gene Promoter Region With Der p 2 Allergy
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Liao EC, Chang CY, Wu CC, Wang GJ, Tsai JJ
- KMID: 2260462
- Allergy Asthma Immunol Res.
- 2015 May;7(3):249-255.
- doi: 10.4168/aair.2015.7.3.249
PURPOSE: Sensitization to house dust mite (Dermatophagoides pteronyssinus) is a considerable risk factor for the progression of allergic disease. The group 2 allergen from Dermatophagoides pteronyssinus, Der p 2, is... -
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- Der p2 Internalization by Epithelium Synergistically Augments Toll-like Receptor-Mediated Proinflammatory Signaling
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Yin SC, Liao EC, Chiu CL, Chang CY, Tsai JJ
- KMID: 2166687
- Allergy Asthma Immunol Res.
- 2015 Jul;7(4):393-403.
- doi: 10.4168/aair.2015.7.4.393
PURPOSE: House-dust-mite (HDM) major allergen Der p2 shares homology and function with Toll-like receptor (TLR) signaling protein myeloid differentiation-2 (MD2) and may lead to airway inflammation. Should Der p2 be... -
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