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Adipose Tissue-Derived Stem Cells from Type 2 Diabetics Reveal Conservative Alterations in Multidimensional Characteristics

Wang L, Zhang L, Liang X, Zou J, Liu N, Liu T, Wang G, Ding X, Liu Y, Zhang B, Liang R, Wang S

Background and Objectives: Adipose tissue-derived mesenchymal stem cells (ASCs) are recognized as an advantaged source for the prevention and treatment of diverse diseases including type 2 diabetes mellitus (T2DM). However,...
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Patchy echogenicity of the liver in patients with chronic hepatitis B does not indicate poorer elasticity

Wu S, Tu R, Liang X

PURPOSE: This study was conducted to investigate whether the presence of patchy echogenicity in the liver of patients with chronic hepatitis B (CHB) is predictive of liver stiffness. METHODS: A total...
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Impact of variations in fatty liver on sonographic detection of focal hepatic lesions originally identified by CT

Wu S, Tu R, Nan R, Liu G, Cui X, Liang X

PURPOSE: The aim of this study was to investigate the influence of variations in fatty liver on the ultrasonographic detection of focal liver lesions. METHODS: A total of 229 patients with...
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Erector spinae plane block for spinal surgery: a systematic review and meta-analysis

Liang X, Zhou W, Fan Y

Background: Although the erector spinae plane block has been used in various truncal surgical procedures, its clinical benefits in patients undergoing spinal surgery remain controversial. The aim of this meta-analysis...
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Measurement of elasticity of normal placenta using the Virtual Touch quantification technique

Wu S, Nan R, Li Y, Cui X, Liang X, Zhao Y

PURPOSE: The aim of this study was to measure the elasticity of normal placentas using the Virtual Touch quantification (VTQ) technique. METHODS: This study was approved by the Institutional Ethics Committee....
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Transcriptome Sequencing Reveals the Potential Mechanisms of Modified Electroconvulsive Therapy in Schizophrenia

Peng W, Tan Q, Yu M, Wang P, Wang T, Yuan J, Liu D, Chen D, Huang C, Tan Y, Liu K, Xiang B, Liang X

Objective Schizophrenia (SCZ) is one of the most common and severe mental disorders. Modified electroconvulsive therapy (MECT) is the most effective therapy for all kinds of SCZ, and the underlying...
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Silencing the PIK3CA Gene Enhances the Sensitivity of Childhood Leukemia Cells to Chemotherapy Drugs by Suppressing the Phosphorylation of Akt

Liang X, Xin X, Qi D, Fu C, Ding M

PURPOSE: This study aimed to investigate the effects of PIK3CA on the sensitivity of acute B lymphocytic leukemia cells (Nalm-6 cells) to chemotherapy drugs. MATERIALS AND METHODS: Children's normal B lymphocytes...
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Therapeutic inhibition of SGK1 suppresses colorectal cancer

Liang X, Lan C, Jiao G, Fu W, Long X, An Y, Wang K, Zhou J, Chen T, Li Y, Xu J, Huang Q, Xu B, Xiao J

Colorectal cancer (CRC) is one of the leading causes of death worldwide. Thus, the development of new therapeutic targets for CRC treatment is urgently needed. SGK1 is involved in various...
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Propylthiouracil, Perchlorate, and Thyroid-Stimulating Hormone Modulate High Concentrations of Iodide Instigated Mitochondrial Superoxide Production in the Thyroids of Metallothionein I/II Knockout Mice

Duan Q, Wang T, Zhang N, Perera V, Liang X, Abeysekera IR, Yao X

BACKGROUND: Increased oxidative stress has been suggested as one of the underlying mechanisms in iodide excess-induced thyroid disease. Metallothioneins (MTs) are regarded as scavengers of reactive oxygen species (ROS) in...
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In vitro differentiation of spermatogonial stem cells using testicular cells from Guangxi Bama mini-pig

Zhao H, Nie J, Zhu X, Lu Y, Liang X, Xu H, Yang X, Zhang Y, Lu K, Lu S

In this study, we attempted to establish a culture system for in vitro spermatogenesis from spermatogonial stem cells (SSCs) of Bama mini-pig. Dissociated testicular cells from 1-month-old pigs were co-cultured...
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Antiviral effects of Bovine antimicrobial peptide against TGEV in vivo and in vitro

Liang X, Zhang X, Lian K, Tian X, Zhang M, Wang S, Chen C, Nie C, Pan Y, Han F, Wei Z, Zhang W

Background: In suckling piglets, transmissible gastroenteritis virus (TGEV) causes lethal diarrhea accompanied by high infection and mortality rates, leading to considerable economic losses. This study explored methods of preventing or...
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