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Detection of point mutation at C-terminal region of phagosomal coat protein (TACO) in patients with leprosy

Kim SK, Kang TJ, Kim BC, Chae GT

  • KMID: 1516979
  • Korean Lepr Bull.
  • 2003 Jul;36(1):11-26.
Mycobacteria, which are highly successful pathogen, resist delivary to lysosomes and instead survive within a specialized vacuole, the mycobacterial phagosome. The bacteria survive intracellularly because they are able to actively...
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The centrosomal localization of KM-HN-1 (MGC33607) depends on the leucine zipper motif and the C-terminal coiled-coil domain

Park HJ, Seo HJ, Kim HW, Kim JS, Hwang SY, Seong YS

  • KMID: 1091078
  • Exp Mol Med.
  • 2007 Dec;39(6):828-838.
KM-HN-1 is a C-terminal coiled-coil domain containing protein previously referred to as image clone MGC33607. This protein has been previously identified as a cancer/testis antigen and reported as nuclear and...
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SoxD Transcription Factors: Multifaceted Players of Neural Development

Ji EH, Kim J

SoxD transcription factor subfamily includes three members, Sox5, Sox6, and Sox13. Like other Sox genes, they contain the High-Mobility-Group (HMG) box as the DNA binding domain but in addition feature...
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Effect of MITF-M and MITF-A Overexpression on the Dendrtic Formation in Melanocytes

Jo IS, Sohn KC, Kim CD, Lee YH

The microphthalmia-associated transcription factor (MITF), has been described as the master regulator of the basic helix-loop-helix leucine zipper family, involves melanogenesis in melanocytes. MITF consists of at least six isoforms,...
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IKKγ Facilitates the Activation of NF-κB by Hepatitis C Virus Core Protein

Kang BY, Lee SY, Kim JI, Choi HJ, Joo WH, Kim DW

Hepatitis C virus (HCV) is a major cause of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. HCV core protein has been shown to modulate various cellular signaling pathways including the...
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Expression of a Functional zipFv Antibody Fragment and Its Fusions with Alkaline Phosphatase in the Cytoplasm of an Escherichia coli

Hur BU, Choi HJ, Yoon JB, Cha SH

BACKGROUND: Expression of recombinant antibodies and their derivatives fused with other functional molecules such as alkaline phosphatase in Escherichia coli is important in the development of molecular diagnostic reagents for...
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Bovine adenovirus type 3 virions cannot be rescued in vivo after full-length viral genome transfection in the absence of detectable polypeptide IX

Zhang P, Xue Q, Ma J, Ren J, Xia S, Zhang L, Wang W, Tikoo SK, Du E

Bovine adenovirus type 3 (BAdV3) is being used in the development of potential vehicles for gene therapy and vectored vaccine. To that end, a more comprehensive description of BAdV3 biology...
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Engagement of CD99 Reduces AP-1 Activity by Inducing BATF in the Human Multiple Myeloma Cell Line RPMI8226

Gil M, Pak HK, Park SJ, Lee AN, Park YS, Lee H, Lee H, Kim KE, Lee KJ, Yoon DH, Chung YS, Park CS

CD99 signaling is crucial to a diverse range of biological functions including survival and proliferation. CD99 engagement is reported to augment activator protein-1 (AP-1) activity through mitogen-activated protein (MAP) kinase...
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Association Study of FOS-Like Antigen-2 Promoter Polymorphisms With Papillary Thyroid Cancer in Korean Population

Kim SW, Kim CD, Chung JH, Kwon KH

  • KMID: 2278403
  • Clin Exp Otorhinolaryngol.
  • 2014 Mar;7(1):42-46.
OBJECTIVES: FOS-like antigen-2 (FOSL-2), a member of the FOS gene family, encode leucine zipper proteins that can heterodimerize with proteins of Jun family. Thus, activating protein (AP)-1 transcription factor is...
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Evaluation of the role of TAX, HBZ, and HTLV-1 proviral load on the survival of ATLL patients

Akbarin MM, Shirdel A, Bari A, Mohaddes S, Rafatpanah H, Karimani E, Etminani K, Golabpour , Torshizi R

BACKGROUND: Adult T-cell leukemia/lymphoma (ATLL) is an aggressive malignancy with very poor prognosis and short survival, caused by the human T-lymphotropic virus type-1 (HTLV-1). The HTLV-1 biomarkers trans-activator x (TAX)...
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