- A Histological Study on the Bone Tissues Surrounding Coated and Non-Coated Titanium Implants in Beagle Dogs
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Leem SH, Son SH
- KMID: 1959417
- J Korean Acad Periodontol.
- 1997 Mar;27(1):91-109.
- doi: 10.5051/jkape.1997.27.1.91
No abstract available. -
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- An improved method for quantitative sugar analysis of glycoproteins
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Kim S, Kim SH, Kim SI, Ha KS, Leem SH
- KMID: 755078
- Exp Mol Med.
- 2000 Sep;32(3):141-145.
Although there are numerous methods available to hydrolyze glycans utilizing strong acids, it all requires lengthy steps to obtain quantitative yield. We have developed a new simple one-step method for... -
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- Medullary Sponge Kidney Detected in the Pediatric Age
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Chung WY, Cho MH, Gu YR, Leem SH, Cheong HI
- KMID: 2322034
- J Korean Soc Pediatr Nephrol.
- 2012 Oct;16(2):109-114.
PURPOSE: Medullary sponge kidney (MSK) is a rare congenital disease characterized by diffuse ectasia or dilatation of precalyceal collecting tubules. MSK incidence and prevalence in the general population is uncertain... -
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- Gecko Proteins Exert Anti-Tumor Effect against Cervical Cancer Cells Via PI3-Kinase/Akt Pathway
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Jeong AJ, Chung CN, Kim HJ, Bae KS, Choi S, Jun WJ, Shim SI, Kang TH, Leem SH, Chung JW
- KMID: 1493971
- Korean J Physiol Pharmacol.
- 2012 Oct;16(5):361-365.
- doi: 10.4196/kjpp.2012.16.5.361
Anti-tumor activity of the proteins from Gecko (GP) on cervical cancer cells, and its signaling mechanisms were assessed by viable cell counting, propidium iodide (PI) staining, and Western blot analysis.... -
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- Auranofin Enhances Sulforaphane-Mediated Apoptosis in Hepatocellular Carcinoma Hep3B Cells through Inactivation of the PI3K/Akt Signaling Pathway
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Hwangbo H, Kim SY, Lee H, Park SH, Hong SH, Park C, Kim GY, Leem SH, Hyun JW, Cheong J, Choi YH
- KMID: 2505690
- Biomol Ther.
- 2020 Sep;28(5):443-455.
- doi: 10.4062/biomolther.2020.122
The thioredoxin (Trx) system plays critical roles in regulating intracellular redox levels and defending organisms against oxidative stress. Recent studies indicated that Trx reductase (TrxR) was overexpressed in various types... -
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- Genomic biomarkers to predict response to atezolizumab plus bevacizumab immunotherapy in hepatocellular carcinoma: Insights from the IMbrave150 trial
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Yim SY, Lee SH, Baek SW, Sohn B, Jeong YS, Kang SH, Park K, Park H, Lee SS, Kaseb AO, Park YN, Leem SH, Curran MA, Kim JH, Lee JS
- KMID: 2560087
- Clin Mol Hepatol.
- 2024 Oct;30(4):807-823.
- doi: 10.3350/cmh.2024.0333
Background/Aims: Combination immunotherapy, exemplified by atezolizumab plus bevacizumab, has become the standard of care for inoperable hepatocellular carcinoma (HCC). However, the lack of predictive biomarkers and limited understanding of response... -
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- Pro-oncogenic potential of NM23-H2 in hepatocellular carcinoma
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Lee MJ, Xu DY, Li H, Yu GR, Leem SH, Chu IS, Kim IH, Kim DG
- KMID: 1245264
- Exp Mol Med.
- 2012 Mar;44(3):214-224.
- doi: 10.3858/emm.2012.44.3.016
NM23 is a family of structurally and functionally conserved proteins known as nucleoside diphosphate kinases (NDPK). There is abundant mRNA expression of NM23-H1, NM23-H2, or a read through transcript (NM23-LV)... -
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- Association between job-related stress and experience of presenteeism among Korean workers stratified on the presence of depression
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Kim J, Kim YK, Leem SH, Won JU
- KMID: 2466070
- Ann Occup Environ Med.
- 2019 ;31(1):e26.
- doi: 10.35371/aoem.2019.31.e26
BACKGROUND: Presenteeism refers to the phenomenon of working while sick. Its development can be attributed to not only somatic symptoms but also underlying social agreements and workplace atmosphere. In this... -
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- A polymorphic minisatellite region of BORIS regulates gene expression and its rare variants correlate with lung cancer susceptibility
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Yoon SL, Roh YG, Chu IS, Heo J, Kim SI, Chang H, Kang TH, Chung JW, Koh SS, Larionov V, Leem SH
- KMID: 2361533
- Exp Mol Med.
- 2016 Jul;48(7):e246.
- doi: 10.1038/emm.2016.50
Aberrant expression of BORIS/CTCFL (Brother of the Regulator of Imprinted Sites/CTCF-like protein) is reported in different malignancies. In this study, we characterized the entire promoter region of BORIS/CTCFL, including the... -
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- Genes Associated with Recurrence of Hepatocellular Carcinoma: Integrated Analysis by Gene Expression and Methylation Profiling
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Yang JD, Seol SY, Leem SH, Kim YH, Sun Z, Lee JS, Thorgeirsson SS, Chu IS, Roberts LR, Kang KJ
- KMID: 1123442
- J Korean Med Sci.
- 2011 Nov;26(11):1428-1438.
- doi: 10.3346/jkms.2011.26.11.1428
Gene expression is suppressed by DNA methylation. The goal of this study was to identify genes whose CpG site methylation and mRNA expression are associated with recurrence after surgical resection... -
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