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Metformin Ameliorates Lipotoxic β-Cell Dysfunction through a Concentration-Dependent Dual Mechanism of Action

Kim HI, Lee JS, Kwak BK, Hwang WM, Kim MJ, Kim YB, Chung SS, Park KS

BACKGROUND: Chronic exposure to elevated levels of free fatty acids contributes to pancreatic β-cell dysfunction. Although it is well known that metformin induces cellular energy depletion and a concomitant activation...
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TERT Promoter Mutations and Tumor Persistence/Recurrence in Papillary Thyroid Cancer

Myung JK, Kwak BK, Lim JA, Lee MC, Kim MJ

PURPOSE: A telomerase reverse transcriptase (TERT) promoter mutation was identified in thyroid cancer. This TERT promoter mutation is thought to be a prognostic molecular marker, because its association with tumor...
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Evaluation of Engraftment of Superparamagnetic Iron Oxide-Labeled Mesenchymal Stem Cells Using Three-Dimensional Reconstruction of Magnetic Resonance Imaging in Photothrombotic Cerebral Infarction Models of Rats

Shim J, Kwak BK, Jung J, Park S

OBJECTIVE: To evaluate engraftment by visualizing the location of human bone marrow-derived mesenchymal stem cells (hBM-MSCs) three-dimensionally in photothrombotic cerebral infarction (PTCI) models of rats. MATERIALS AND METHODS: Magnetic resonance imaging...
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Engraftment of Human Mesenchymal Stem Cells in a Rat Photothrombotic Cerebral Infarction Model : Comparison of Intra-Arterial and Intravenous Infusion Using MRI and Histological Analysis

Byun JS, Kwak BK, Kim JK, Jung J, Ha BC, Park S

OBJECTIVE: This study aimed to evaluate the hypotheses that administration routes [intra-arterial (IA) vs. intravenous (IV)] affect the early stage migration of transplanted human bone marrow-derived mesenchymal stem cells (hBM-MSCs)...
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A Case of Carcinosarcoma of the Parotid Gland

Park DU, Kwak BK, Woo JH, Kim DY

Carcinosarcoma is an extremely rare tumor, composed of a mixture of both carcinomatous and sarcomatous elements. The two-thirds are derived from the parotid gland. Because carcinosarcoma is highly aggressive malignant...
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Modeling Human Exposure Levels to Airborne Volatile Organic Compounds by the Hebei Spirit Oil Spill

Kim JH, Kwak BK, Ha M, Cheong HK, Yi J

  • KMID: 2380175
  • Environ Health Toxicol.
  • 2012 ;27(1):e2012008.
OBJECTIVES: The goal was to model and quantify the atmospheric concentrations of volatile organic compounds (VOCs) as the result of the Hebei Spirit oil spill, and to predict whether the...
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Pulmonary Lipiodol Accumulation after Transarterial Chemoembolization: CT Findings and Its Radiologic Outcomes

Youn I, Chong S, Kwak BK, Shim HJ, Seo GY, Seo JS, Kim JK

PURPOSE: To evaluate CT findings and radiologic outcomes of pulmonary lipiodol accumulation (PLA) after transarterial chemoembolization (TACE). MATERIALS AND METHODS: This retrospective study involved 488 TACEs for hepatocellular carcinoma (HCC) (n...
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Transcatheter Arterial Embolization in Patients with Kidney Diseases: an Overview of the Technical Aspects and Clinical Indications

Loffroy R, Rao P, Kwak BK, Ota S, Lin MD, Liapi E, Geschwind

Therapeutic embolization is defined as the voluntary occlusion of one or several vessels, and this is achieved by inserting material into the lumen to obtain transient or permanent thrombosis in...
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In vivo Tracking of Mesenchymal Stem Cells Labeled with a Novel Chitosan-coated Superparamagnetic Iron Oxide Nanoparticles using 3.0T MRI

Reddy AM, Kwak BK, Shim HJ, Ahn C, Lee HS, Suh YJ, Park ES

This study aimed to characterize and MRI track the mesenchymal stem cells labeled with chitosan-coated superparamagnetic iron oxide (Chitosan-SPIO). Chitosan-SPIO was synthesized from a mixture of FeCl2 and FeCl3. The...
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Contrast Extravasation into an Acute Spontaneous Intracerebral Hematoma: Multidetector CT Angiographic Findings and Clinical Implications

Kim SE, Yu H, Baik HW, Lee HY, Kwak BK, Lee JB, Kim YS, Lee YC

PURPOSE: The purpose of this study was to evaluate multidetector row CT (MDCT) angiographic findings and their clinical significance for contrast extravasation into a spontaneous intracerebral hematoma (ICH). MATERIALS AND...
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Immunohistological Study of the Effects of Intranasal ZnSO4 Instillation on the Mouse Olfactory Epithelium and Olfactory Bulb

Kim MW, Moon YW, Kim BG, Kwak BK, Park YJ

  • KMID: 2276620
  • Korean J Otolaryngol-Head Neck Surg.
  • 2006 Apr;49(4):395-401.
BACKGROUND AND OBJECTIVES: The purpose of this study was to evaluate the time course of functional and anatomical recovery of the olfactory epithelium (OE) and olfactory bulb (OB) following intranasal...
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Comparison of the CT and Pathologic Findings of Pulmonary Fat Embolism Induced by Triolein and Oleic Acid in Rabbits

Baik HW, Yoo SM, Lee HY, Song IS, Yu H, Lee JB, Kim YS, Kwak BK, Shim HJ, Kim KS, Lee YC, Lee TJ, Sung DW

PURPOSE: The aim of this study was to evaluate the CT findings of pulmonary fat embolism syndrome that was induced by triolein and oleic acid, along with its pathologic...
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Magnetic Resonance Imaging in Facial Nerve Palsy: Comparison between Bell's Palsy and Herpes Zoster Oticus

Park SN, Kim HS, Jung SL, Park KH, Kim BS, Kwak BK, Park JO, Lee SE, Yeo SW

  • KMID: 2276435
  • Korean J Otolaryngol-Head Neck Surg.
  • 2005 Jul;48(7):854-858.
BACKGROUND AND OBJECTIVES: Magnetic resonance imaging (MRI) is a valuable and important tool for use in diagnosing and investigating diseases affecting the facial nerve. However, there are few reports investigating...
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Ultrasound-Guided Radiofrequency Ablation of Thyroid Gland: A Preliminary Study in Dogs

Choi JW, Kwak SH, Yoo SM, Song IS, Lee HY, Lee JB, Shim HJ, Kwak BK, Kim YS, Lee YC, Kim KS, Lee TJ

PURPOSE: The purpose of this study was to evaluate the possibility of using radiofrequency ablation as the treatment modality for the benign or malignant thyroid nodules in humans. Therefore, we...
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Fixation Methods for Implantable Port Chamber: Comparative Study Using Glue, Self-stabilizing Leg and Suture Fixations in Rabbits

Na HI, Shim HJ, Kwak BK, Kim HJ, Lee YC

OBJECTIVE: To evaluate the fixation strength and tissue reaction of the glue fixation and self-stabilizing leg fixation methods and to compare the results with those of the conventional tagging suture...
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Micro-pleural Metastasis Without Effusion: CT and US Findings

Na HI, Yoo SM, Kim YS, Lee HY, Song IS, Shim HJ, Kwak BK, Shin JW

  • KMID: 2001005
  • J Korean Soc Med Ultrasound.
  • 2004 Sep;23(3):169-172.
Pleural metastasis from malignancy is commonly combined with effusion. We report the ultra-sonographic and CT findings in a rare case of micro-pleural metastasis without effusion.A 34-year-old male patient with lung...
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Hepatic CT Enhancement: Comparison between Dimeric and Monomeric Nonionic Contrast Agents in Rabbits

Kim GH, Kwak BK, Shim HJ, Kim KN, Liu WC, Ryu SH, Kim YS, Lee JB, Kim KS

PURPOSE: To determine the hepatic and vascular enhancement profiles with nonionic dimeric, iodixanol, contrast agent in the rabbit and to compare them with nonionic monomeric, ioversol, contrast agent. MATERIALS AND METHODS:...
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A Comparative Study of Intra-arterial and Intramuscular Administration of phVEGF165 in a Chronic Ischemic Model of Rabbit Hindlimb

Kwak BK, Shim HJ, Kim KS, Lee JB, Song IS, Moon YH, Kim DH, Kim SW, Kim JS, Chung JW, Park JH

PURPOSE: To obtain phVEGF165 for angiogenesis and to compare the effects of its intra-arterial and intramuscular administration in a chronic ischemic rabbit hindimb model. MATERIALS AND METHODS: Chronic ischemic models...
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Radial Artery Approach for Transcatheter Arterial Chemoembolization in Patients with Hepatocellular Carcinoma

Ryu SH, Shim HJ, Kwak BK, Kim GH, Lee HY, Song IS, Kim YS

PURPOSE: To evaluate the feasibility and usefulness of the transradial approach for intra-arterial chemoembolization therapy in patients with hepatocellular carcinomas. MATERIALS AND METHODS: Twenty-nine patients with hepatocellular carcinoma who underwent intra-arterial...
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An experimental model of ischemia in rabbit hindlimb

Hong JH, Bahk YW, Suh JS, Kwak BK, Shim HJ, Kim JS, Kim HS, Moon YH, Kim SJ, Chung JW, Park JH

This study was performed to establish an experimental model of ischemia for the investigation of new treatment modality of limb-threatening ischemia. We produced ischemia in the hindlimbs of 8 New...
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