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Glucagon-Like Peptide-1 Receptor Agonist Differentially Affects Brain Activation in Response to Visual Food Cues in Lean and Obese Individuals with Type 2 Diabetes Mellitus

Bae JH, Choi HJ, Cho KIK, Kim LK, Kwon JS, Cho YM

Background: To investigate the effects of a glucagon-like peptide-1 receptor agonist on functional brain activation in lean and obese individuals with type 2 diabetes mellitus (T2DM) in response to visual...
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Genetic Profiles Associated with Chemoresistance in Patient-Derived Xenograft Models of Ovarian Cancer

Li LY, Kim HJ, Park SA, Lee SH, Kim LK, Lee JY, Kim S, Kim YT, Kim SW, Nam EJ

PURPOSE: Recurrence and chemoresistance (CR) are the leading causes of death in patients with high-grade serous carcinoma (HGSC) of the ovary. The aim of this study was to identify genetic...
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Components of Metabolic Syndrome in Korean Adults: A Hospital-Based Cohort at Seoul National University Bundang Hospital

Lim S, Min SH, Lee JH, Kim LK, Lee DH, Lee JE, Kim KM, Lee S, Park KC, Lee YJ

BACKGROUND: The prevalence of metabolic syndrome is increasing in Korea, particularly among young adults. This trend will increase the incidence of cardiovascular and metabolic diseases in the future. Therefore, it...
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COPD as a Disease of Immunosenescence

Cho WK, Lee CG, Kim LK

Although chronic obstructive pulmonary disease (COPD) is regarded as a chronic inflammatory lung disease, the disease mechanism is still not known. Intriguingly, aging lungs are quite similar to COPD-affected lungs...
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Integrin CD11b negatively regulates Mincle-induced signaling via the Lyn–SIRPα–SHP1 complex

Zhang Q, Lee WB, Kang JS, Kim LK, Kim YJ

During mycobacteria infection, anti-inflammatory responses allow the host to avoid tissue damage caused by overactivation of the immune system; however, little is known about the negative modulators that specifically control...
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Beyond the Role of CD55 as a Complement Component

Dho SH, Lim JC, Kim LK

The complement is a part of the immune system that plays several roles in removing pathogens. Despite the importance of the complement system, the exact role of each component has...
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Long Non-coding RNA HOXA11 Antisense Promotes Cell Proliferation and Invasion and Predicts Patient Prognosis in Serous Ovarian Cancer

Yim GW, Kim HJ, Kim LK, Kim SW, Kim S, Nam EJ, Kim YT

PURPOSE: The biological function of long non-coding RNAs (lncRNAs) is only partially understood; therefore, in this study, we investigated the expression of the novel HOXA11 antisense (HOXA11as) lncRNA and its...
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Erratum: Correction of Figure: Clinical Implications of Various Criteria for the Biochemical Diagnosis of Insulinoma

Ahn CH, Kim LK, Lee JE, Jung CH, Min SH, Park KS, Kim SY, Cho YM

In the original article, the legend of Fig. 1 was incorrect. The solid line was noninsulinoma, and the dotted line was insulinoma.
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Effect of different adhesive systems and post surface treatments on the push-out bond strengths of fiber-reinforced post

Kim MW, Ahn JH, Kim LK, Shim HW

PURPOSE: The purpose of this study was to evaluate the push-out bond strength of glass-fiber post cemented with different adhesive systems and surface treatments. MATERIALS AND METHODS: 160 tooth samples made...
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Improving Effect of the Acute Administration of Dietary Fiber-Enriched Cereals on Blood Glucose Levels and Gut Hormone Secretion

Kim EK, Oh TJ, Kim LK, Cho YM

Dietary fiber improves hyperglycemia in patients with type 2 diabetes through its physicochemical properties and possible modulation of gut hormone secretion, such as glucagon-like peptide 1 (GLP-1). We assessed the...
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A Case of MELAS Syndrome Presenting with Type 1 Diabetes Mellitus

Jung CH, Roh E, Ahn CH, Kim LK, Lim S, Jang HC, Choi SH

Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome presents with various clinical features, including seizures, stroke-like episodes, encephalopathy, myopathy, cardiac involvement, and diabetes. However, due to its clinical heterogeneity,...
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Protective effect of butylated hydroxylanisole against hydrogen peroxide-induced apoptosis in primary cultured mouse hepatocytes

Hwang GH, Jeon YJ, Han HJ, Park SH, Baek KM, Chang W, Kim JS, Kim LK, Lee YM, Lee S, Bae JS, Jee JG, Lee MY

Butylated hydroxyanisole (BHA) is a synthetic phenolic compound consisting of a mixture of two isomeric organic compounds: 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole. We examined the effect of BHA against hydrogen peroxide (H2O2)-induced...
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Case Report of Everolimus-Associated DKA in a Patient with Metastatic Renal Cell Carcinoma

Kim LK, Ahn CH, Lee JE, Jung CH, Koo BK, Moon MK

  • KMID: 2269343
  • Korean J Med.
  • 2014 Jun;86(6):761-765.
Everolimus, an inhibitor of the mammalian target of the rapamycin (mTOR) pathway, is widely used as an immunosuppressant for the prevention of organ rejection following transplant and to treat metastatic...
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Clinical Implications of Various Criteria for the Biochemical Diagnosis of Insulinoma

Ahn CH, Kim LK, Lee JE, Jung CH, Min SH, Park KS, Kim SY, Cho YM

BACKGROUND: Among the various diagnostic criteria for insulinoma, the ratio criteria have been controversial. However, the amended insulin-glucose ratio exhibited excellent diagnostic performance in a recent retrospective cohort study, although...
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A Case of Acute Liver Failure Associated with Methimazole in Patient with Underlying Liver Disease

Lee JE, Kim YA, Kim LK, Park YJ

We report a case of methimazole-induced acute hepatic failure, which occurred 4 days after initiation of drug in a 51-year-old man with hyperthyroidism. Liver function was evaluated before taking methimazole,...
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Osseointegration of zirconia implant in the tibia of pigs

Kim LK, Cho IH

PURPOSE: The purposes of this study were to investigate osseointegration around zirconia implants which had machined or alumina sandblasted surface, and to compare the results with titanium implants. MATERIALS AND METHODS:...
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A Novel Mutation in the Von Hippel-Lindau Tumor Suppressor Gene Identified in a Patient Presenting with Gestational Diabetes Mellitus

Ku YH, Ahn CH, Jung CH, Lee JE, Kim LK, Kwak SH, Jung HS, Park KS, Cho YM

BACKGROUND: Von Hippel-Lindau (VHL) disease is an autosomal dominantly inherited, multisystemic tumor syndrome caused by mutations in the VHL gene. To date, more than 1,000 germline and somatic mutations of...
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Analysis of Influencing Factors to Depth of Epidural Space for Lumbar Transforaminal Epidural Block in Korean

Kim LK, Kim JR, Shin SS, Kim IJ, Kim BN, Hwang GT

BACKGROUND: Transforaminal epidural steroid injection is one of the effective treatments in managing radicular pain. There have been some prospective studies on the depth to the epidural space with the...
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Hydrothorax due to extravasation of intravenous contrast through left subclavian catheter -A case report-

Choi JG, Choi JS, Park CH, Lee CS, Kim LK, Chung YR

Central venous catheterization is associated with a large number of complications, such as pneumothorax, hydrothorax, hemothorax, phlebothrombosis, pericardial tamponade, air embolism, aberrant placement and line sepsis. There are many case...
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Development of multifocal atrial tachycardia in a patient using aminophylline: A case report

Kim LK, Lee CS, Jeun JG

An 82-year-old female, with left femoral neck fracture was scheduled for left hip hemiarthroplasty, under spinal anaesthesia. She had been suffering from diabetes, hypertension, lung cancer and was previously treated...
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