- Determination of serum isocitrate dehydrogenase activities in thedifferentation of contrilobular from periportal hepatic necrosis in rats
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Chung YH, Yang SK, Min YI, Lee IC
- KMID: 1685471
- Korean J Gastroenterol.
- 1992 Oct;24(5):1023-1030.
No abstract available. -
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- In-Vivo Proton Magnetic Resonance Spectroscopy of 2-Hydroxyglutarate in Isocitrate Dehydrogenase-Mutated Gliomas: A Technical Review for Neuroradiologists
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Kim H, Kim S, Lee HH, Heo H
- KMID: 2458053
- Korean J Radiol.
- 2016 Oct;17(5):620-632.
- doi: 10.3348/kjr.2016.17.5.620
The diagnostic and prognostic potential of an onco-metabolite, 2-hydroxyglutarate (2HG) as a proton magnetic resonance spectroscopy (1H-MRS) detectable biomarker of the isocitrate dehydrogenase (IDH)-mutated (IDH-MT) gliomas has drawn attention of... -
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- IDH Mutation Analysis in Ewing Sarcoma Family Tumors
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Na KY, Noh BJ, Sung JY, Kim YW, Santini Araujo E, Park YK
- KMID: 2381385
- J Pathol Transl Med.
- 2015 May;49(3):257-261.
- doi: 10.4132/jptm.2015.04.14
BACKGROUND: Isocitrate dehydrogenase (IDH) catalyzes the oxidative decarboxylation of isocitrate to yield alpha-ketoglutarate (alpha-KG) with production of reduced nicotinamide adenine dinucleotide (NADH). Dysfunctional IDH leads to reduced production of alpha-KG... -
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- Clinical usefulness of serum isocitrate dehydrognase as a marker of centrilobular hepatic necrosis in patients with hyperthyroidism
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Choi WB, Chung YH, Jung SA, Song BC, Kim JA, Kim JW, Song IH, Chang WY, Shong YK, Lee YS, Suh DJ
- KMID: 2306235
- Korean J Med.
- 2000 Feb;58(2):189-196.
BACKGROUND: The zonal differentiation of hepatic necrosis is important in the aspect of treatment, follow-up and prognosis of patients. The purpose of this study was evaluating the clinical usefulness of serum isocitrate... -
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- A Survey of the Neuro-Oncology Landscape
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Lukas RV, Wu J, Dey M, Buerki RA, Byrne RW, Dohrmann G
- KMID: 2399593
- J Clin Neurol.
- 2018 Jan;14(1):8-15.
- doi: 10.3988/jcn.2018.14.1.8
The field of neuro-oncology is evolving rapidly. Many important advances have recently been reported, and other promising investigations have the potential to soon make substantial impacts in the field, especially... -
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- Reclassification of Mongolian Diffuse Gliomas According to the Revised 2016 World Health Organization Central Nervous System Tumor Classification
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Ochirjav E, Enkhbat B, Baldandorj T, Choe G
- KMID: 2459578
- J Pathol Transl Med.
- 2019 Sep;53(5):298-307.
- doi: 10.4132/jptm.2019.07.15
BACKGROUND: The 2016 World Health Organization (WHO) classification of central nervous system (CNS) tumors has been modified to incorporate the IDH mutation and 1p/19q co-deletion in the diagnosis of diffuse... -
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- Application of Volumetric Analysis to Glioblastomas: a Correlation Study on the Status of the Isocitrate Dehydrogenase Mutation
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Bae SY, Park CK, Kim TM, Park SH, Kim IH, Choi SH
- KMID: 2151768
- Investig Magn Reson Imaging.
- 2015 Dec;19(4):218-223.
- doi: 10.13104/imri.2015.19.4.218
PURPOSE: To investigate whether volumetric analysis based on T2WI and contrast-enhanced (CE) T1WI can distinguish between isocitrate dehydrogenase-1 mutation-positive (IDH1(P)) and -negative (IDH1(N)) glioblastomas (GBMs). MATERIALS AND METHODS: We retrospectively enrolled... -
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- Immunohistochemical Analysis of ATRX, IDH1 and p53 in Glioblastoma and Their Correlations with Patient Survival
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Chaurasia , Park SH, Seo JW, Park CK
- KMID: 2373747
- J Korean Med Sci.
- 2016 Aug;31(8):1208-1214.
- doi: 10.3346/jkms.2016.31.8.1208
Glioblastoma (GBM) can be classified into molecular subgroups, on the basis of biomarker expression. Here, we classified our cohort of 163 adult GBMs into molecular subgroups according to the expression... -
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- Malignant Glioma with Neuronal Marker Expression : A Clinicopathological Study of 18 Cases
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Kim HR, Lee JJ, Lee JI, Nam DH, Suh YL, Seol HJ
- KMID: 2152917
- J Korean Neurosurg Soc.
- 2016 Jan;59(1):44-51.
- doi: 10.3340/jkns.2016.59.1.44
OBJECTIVE: Malignant gliomas with neuronal marker expression (MGwNM) are rare and poorly characterized. Increasingly diverse types of MGwNM have been described and these reported cases underscore the dilemmas in the... -
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- Immunohistochemical Classification of Primary and Secondary Glioblastomas
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Lee KS, Choe G, Nam KH, Seo AN, Yun S, Kim KJ, Cho HJ, Park SH
- KMID: 2012155
- Korean J Pathol.
- 2013 Dec;47(6):541-548.
BACKGROUND: Glioblastomas may develop de novo (primary glioblastomas, P-GBLs) or through progression from lower-grade astrocytomas (secondary glioblastomas, S-GBLs). The aim of this study was to compare the immunohistochemical classification of... -
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- Identification of proteins differentially expressed by glutamate treatment in cerebral cortex of neonatal rats
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Kang JB, Park DJ, Koh PO
- KMID: 2470014
- Lab Anim Res.
- 2019 Dec;35(4):172-179.
- doi: 10.1186/s42826-019-0026-9
Glutamate leads to neuronal cell damage by generating neurotoxicity during brain development. The objective of this study is to identify proteins that differently expressed by glutamate treatment in neonatal cerebral... -
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- Membrane Proteome Analysis of Cerulein-Stimulated Pancreatic Acinar Cells: Implication for Early Event of Acute Pancreatitis
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Lee J, Seo JH, Lim JW, Kim H
- KMID: 2167210
- Gut Liver.
- 2010 Mar;4(1):84-93.
BACKGROUND/AIMS: Cerulein pancreatitis is similar to human edematous pancreatitis with dysregulation of the production and secretion of digestive enzymes, edema formation, cytoplasmic vacuolization and the death of acinar cells. We... -
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- Protein Phosphatase Magnesium-Dependent 1δ (PPM1D) Expression as a Prognostic Marker in Adult Supratentorial Diffuse Astrocytic and Oligodendroglial Tumors
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Jeong HJ, Woo CG, Lee B, Khang SK, Nam SJ, Choi J
- KMID: 2408506
- J Pathol Transl Med.
- 2018 Mar;52(2):71-78.
- doi: 10.4132/jptm.2017.10.21
BACKGROUND: Protein phosphatase magnesium-dependent 1δ (PPM1D) is a p53-induced serine/threonine phosphatase, which is overexpressed in various human cancers. A recent study reported that a mutation in the PPM1D gene is... -
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- Comparison of Gene Expression Profile in Eutopic Endometria with or without Endometriosis: A Microarray Study
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Chung MJ, Chung EJ, Lee SJ, Kim MK, Chun SS, Lee TH
- KMID: 2235778
- Korean J Fertil Steril.
- 2007 Mar;34(1):19-31.
OBJECTIVE: Pathogenesis of the endometriosis is very complex and the etiology is still unclear. Our hypothesis is that there may be some difference in gene expression patterns between eutopic endometriums... -
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- The Korean Society for Neuro-Oncology (KSNO) Guideline for WHO Grade III Cerebral Gliomas in Adults: Version 2019.01
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Kim YZ, Kim CY, Lim J, Sung KS, Lee J, Oh HJ, Kang SG, Kang SH, Kong DS, Kim SH, Kim SH, Kim SH, Kim YJ, Kim EH, Kim IA, Kim HS, Roh TH, Park JS, Park HJ, Song SW, Yang SH, Yoon WS, Yoon HI, Lee ST, Lee SW, Lee YS, Wee CW, Chang JH, Jung TY, Jung HL, Cho JH, Choi SH, Choi HS, Hong JB, Lim DH, Chung DS, KSNO Guideline Working Group
- KMID: 2461178
- Brain Tumor Res Treat.
- 2019 Oct;7(2):63-73.
- doi: 10.14791/btrt.2019.7.e42
BACKGROUND: There was no practical guideline for the management of patients with central nervous system tumor in Korea in the past. Thus, the Korean Society for Neuro-Oncology (KSNO), a multidisciplinary... -
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- The Korean Society for Neuro-Oncology (KSNO) Guideline for WHO Grade II Cerebral Gliomas in Adults: Version 2019.01
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Kim YZ, Kim CY, Wee CW, Roh TH, Hong JB, Oh HJ, Kang SG, Kang SH, Kong DS, Kim SH, Kim SH, Kim SH, Kim YJ, Kim EH, Kim IA, Kim HS, Park JS, Park HJ, Song SW, Sung KS, Yang SH, Yoon WS, Yoon HI, Lee J, Lee ST, Lee SW, Lee YS, Lim J, Chang JH, Jung TY, Jung HL, Cho JH, Choi SH, Choi HS, Lim DH, Chung DS, KSNO Guideline Working Group
- KMID: 2461179
- Brain Tumor Res Treat.
- 2019 Oct;7(2):74-84.
- doi: 10.14791/btrt.2019.7.e43
BACKGROUND: There was no practical guideline for the management of patients with central nervous system tumor in Korea for many years. Thus, the Korean Society for Neuro-Oncology (KSNO), a multidisciplinary... -
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