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Extended Red Blood Cell Phenotype Matching Is Dependent on Ethnicity and Specificity of RBC Alloantibodies

Kim HY, Chung YN, Cho D

No abstract available.
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Anti-PP₁P(k) (Tj(a)) Antibody in a Korean Female Patient with p Phenotype Confirmed by Genotyping

Kim B, Choi SJ, Cho D, Kim S, Kim HO

In this study, we report a case of anti-PP₁P(k) (Tj(a)) alloantibody with p phenotype detected and confirmed in a 20-year-old Korean woman diagnosed with anemia during long-term rehabilitation treatment due...
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The prevalence and risk factors of inhibitor development of FVIII in previously treated patients with hemophilia A

Kim JY, You CW

BACKGROUND: Risk factors for the development of inhibitors in previously untreated patients (PUPs) have been reported; this is not the case in previously treated patients (PTPs) owing to fewer studies....
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Alloantibodies to High-Incidence Antigen: Review of Cases and Transfusion Experiences in Korea

Choi SJ, Chung YN, Cho D, Kim S

Antibodies to high-incidence red blood cell antigens should be considered if panagglutination reactions are noted in all panel cells, and negative reactions to autologous red blood cells are detected on...
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Incidence of Red Blood Cell Alloantibody Formation after Platelet Concentrate Transfusions

Park HS, Shin KS, Son BR

BACKGROUND: In platelets transfusion, alloimmunization against the HLA and HPA antigen present in the white blood cells/platelets of the donor blood occurred. In addition, unexpected red blood cell alloantibodies might...
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Prevalence of Unexpected Antibodies in Pregnant Korean Women and Neonatal Outcomes

Yang EJ, Shin KH, Song D, Lee SM, Kim IS, Kim HH, Lee HJ

BACKGROUND: In pregnant women, the frequency of irregular antibodies that cause hemolytic disease of the fetus and newborn (HDFN) vary between study populations. The clinical manifestations of HDFN differ according...
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A Case of Packed red Cell Transfusion-Associated Anti-K Antibody

Kim B

Anti-K alloantibody is a type of red blood cell (RBC) antibody which is generated through immunization. It is well noted that the anti-K antibody causes hemolytic transfusion reactions. Although Koreans...
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Case of Acute Hemolytic Transfusion Reaction due to Anti-Fy(a) Alloantibody in a Patient with Autoimmune Hemolytic Anemia

Choi SJ, Nah H, Kim Y, Kim S, Kim HO

A 72-year-old man with general weakness visited the outpatient clinic of the hematology department. The patient had been treated under the diagnosis of autoimmune hemolytic anemia for 2 years. His...
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Revisiting the Pre-transfusion Test: A Case of Acute Hemolytic Transfusion Reaction due to Multiple Alloantibodies of Anti-E, Anti-c, Anti-Jk(b)

An GD, Kim KH, Jeong IH, Lim HH, Woo KS, Han JY, Kim JM, Jeong JH, Son YK

We report a case of acute hemolytic transfusion reaction due to multiple alloantibodies. A 41-year-old male with multiple histories of transfusion was admitted for jaundice and oliguria after receiving two...
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A Case of Anti-JMH Antibody with High-Titer, Low-Avidity Characteristics: The First Case in Korea

Kim TY, Hong YJ, Kim H, Park KU, Han KS

Anti-John Milton Hagen (JMH) is a high-titer, low-avidity (HTLA) antibody against the high frequency red blood cell (RBC) antigen JMH. It occurs very rarely and has not yet been reported...
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What Is Antibody-Mediated Rejection in Histologic Diagnosis in Liver Recipients?

Lee KB

Antibody-mediated rejection (AMR) is a rare event in liver transplantation compared to other solid organs such as the kidney and heart because of the different immunologic reactions in the liver...
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The Clinical Significance of Implementing Concurrent Direct Antiglobulin Test and Antibody Elution Test in Diagnosing Hemolytic Disease of the Fetus and Newborn

Nah H, Lee E, Song J, Cheong JW, Kim HO

BACKGROUND: Hemolytic disease of the fetus and newborn (HDFN) is a condition in which immune hemolytic anemia occurs in fetuses or newborns as a result of maternal alloimunized antibodies transfer....
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Production of Transfusable Red Blood Cells from Stem Cells

Kim HO

Blood transfusion is a well-established cell therapy. However, blood available for transfusion is a limited resource and is available only through donations by healthy volunteers. Moreover, the perpetual and widespread...
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Human Neutrophil Alloantigen-3a Alloimmunization among Pregnant Korean Women

Han TH, Han KS

BACKGROUND: Alloantibodies against human neutrophil alloantigen (HNA)-3a are associated with severe and fatal transfusion related acute lung injury (TRALI). HNA-3 genotyping and HNA-3a antibody (Ab) identification are essential to diagnosis...
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Red Blood Cell Transfusion in Patients With Autoantibodies: Is It Effective and Safe Without Increasing Hemolysis Risk?

Park SH, Choe WH, Kwon SW

BACKGROUND: The therapeutic efficacy of red blood cell (RBC) transfusions in patients with autoimmune hemolytic anemia (AIHA) is highly debated because of speculations on the increased risk of transfusion reactions;...
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Interlaboratory Comparison of the Results of Lifecodes LSA Class I and Class II Single Antigen Kits for Human Leukocyte Antigen Antibody Detection

Oh EJ, Park H, Park KU, Kang ES, Kim HS, Song EY

BACKGROUND: Although single antigen bead assays (SAB) are approved qualitative tests, the median fluorescence intensity (MFI) values obtained from SAB are frequently used in combination with quantitative significances for diagnostic...
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Performance Evaluation of Unexpected Antibody Screening Test Including Di(a) Cell Using 3% Surgiscreen Sub-Code D in Korean Multi-Transfused Patients

Lee JM, Kim NH, Shin KH, Lee HJ, Chang CL, Lee EY, Kim HH

BACKGROUND: The Dia antigen has been found to have a relatively higher incidence among Korean populations. However, the current popular antibody screening panels contain no Dia positive cells. To prevent...
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Duffy Blood Group Genotyping in Thai Blood Donors

Nathalang , Intharanut K, Siriphanthong K, Nathalang , Kupatawintu P

BACKGROUND: Duffy (FY) blood group genotyping is important in transfusion medicine because Duffy alloantibodies are associated with delayed hemolytic transfusion reactions and hemolytic disease of the fetus and newborn. In...
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The Effect of Bortezomib on Antibody-Mediated Rejection after Kidney Transplantation

Lee J, Kim BS, Park Y, Lee JG, Lim BJ, Jeong HJ, Kim YS, Huh KH

PURPOSE: Recently, bortezomib has been used to treat antibody-mediated rejection (AMR) refractory to conventional treatment such as plasmapheresis, intravenous immunoglobulin, and rituximab. The authors aimed to describe their experiences when...
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False-Positive Reactions Against HLA Class II Molecules Detected in Luminex Single-Antigen Bead Assays

In JW, Rho EY, Shin S, Park KU, Song EY

No abstract available.
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