Korean J Blood Transfus.  2009 Aug;20(2):138-143.

A Case of Simultaneously Detecting Anti-D as an Autoimmune Antibody and Anti-E as an Alloimmune Antibody

Affiliations
  • 1Department of Laboratory Medicine, Ajou University School of Medicine, Suwon, Korea. limyoung@ajou.ac.kr
  • 2Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea.
  • 3Department of Laboratory Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.

Abstract

We report here on a case of simultaneously detecting anti-D as an autoimmune antibody and anti-E as an alloimmune antibody without any evidence of autoimmune hemolytic anemia. A 66-year-old female with tuberculous spondylitis was admitted for removing a previously-placed surgical screw in her spine. She had received antituberculosis drugs and six units of AB, RhD positive packed red blood cells during the previous 6 months. The laboratory findings were as followings: the direct antiglobulin test was positive for IgG, the Rh phenotype of the erythrocytes was typed as group CcDe and RhD antigen was confirmed by the molecular method and the serological method to rule out partial-D.

Keyword

Anti-D; Anti-E; RhD; Autoimmune antibody; Alloimmue antibody

MeSH Terms

Aged
Anemia, Hemolytic, Autoimmune
Coombs Test
Erythrocytes
Female
Humans
Immunoglobulin G
Isoantibodies
Phenotype
Spine
Spondylitis
Immunoglobulin G
Isoantibodies
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