Korean J Blood Transfus.  2008 Dec;19(3):245-249.

A Case of RhD with Anti-D

Affiliations
  • 1Department of Laboratory Medicine, College of Medicine, Korea University, Seoul, Korea. malarim@korea.ac.kr
  • 2Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea.

Abstract

We report here on a case of a RhD blood group phenotype with anti-D. The RhD phenotype for partial D phenotyping with using six monoclonal anti-sera typed as normal RhD for this case. DNA sequencing analysis of the RhD gene covering intron 8 to exon 10 showed two AAATAAGATA insertion sites in intron 8 and a single nucleotide change in the exon 10 area as compared with the normal RhD gene. However, the functional role of the RhD antigen is unclear.

Keyword

RhD; Genotype; Partial D

MeSH Terms

Exons
Genotype
Introns
Isoantibodies
Phenotype
Sequence Analysis, DNA
Isoantibodies
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