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Spontaneous Total Resolution of Severe Lumbar Disc Herniation

Kaliya-Perumal AK, Oh JY

No abstract available.
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Evaluation of Anti-inflammatory and Regenerative Efficiency of Naringin and Naringenin in Degenerated Human Nucleus Pulposus Cells: Biological and Molecular Modeling Studies

Devraj VM, Vemuri SK, Banala RR, Gunda SK, AV GR, GPV S

STUDY DESIGN: Development of an in vitro model for assessing the anti-inflammatory efficacies of naringin (Nar) and naringenin (NG). PURPOSE: To evaluate the efficacy of natural flavonoids as therapeutic drugs against...
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Comparison of Transforming Growth Factor-Beta1 and Lovastatin on Differentiating Mesenchymal Stem Cells toward Nucleus Pulposus-like Phenotype: An In Vitro Cell Culture Study

Yang SH, Yang KC, Chen CW, Huang TC, Sun YH, Hu MH

STUDY DESIGN: In Vitro cell culture study. PURPOSE: This study aims to investigate the impact of transforming growth factor-beta1 (TGF-β1) and lovastatin on differentiating human mesenchymal stem cells (MSCs) toward nucleus...
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Is Adjacent Segment Disease More Frequent in Proximal Levels in Comparison with Distal Levels? Based on Radiological Data of at Least 2 Years Follow Up with More than 2 Level Thoracolumbar Fusions

Kim JH, Ryu DS, Yoon SH

OBJECTIVE: The purpose of this retrospective study was to determine which of the proximal adjacent segment disease (ASD) and distal ASD was more prevalent and what parameters is more related...
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Risk Factors of Secondary Lumbar Discectomy of a Herniated Lumbar Disc after Lumbar Discectomy

Beack JY, Chun HJ, Bak KH, Choi KS, Bae IS, Kim KD

OBJECTIVE: To study risk factors of secondary lumbar discectomy (LD) for recurrent herniated lumbar disc (HLD) and identify methods to lower the rate of recurrence. METHODS: Data from 160 patients who...
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Multifidus Muscles Lipid Content Is Associated with Intervertebral Disc Degeneration: A Quantitative Magnetic Resonance Imaging Study

Ogon I, Takebayashi T, Takashima , Morita T, Oshigiri T, Terashima , Yoshimoto , Yamashita

STUDY DESIGN: Cross-sectional study. PURPOSE: To determine the association between fatty degeneration of the multifidus muscle (Mm) and intervertebral disc degeneration (IVDD) using quantitative magnetic resonance imaging (MRI). OVERVIEW OF LITERATURE: Few...
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Quantitative Predictive Imaging Biomarkers of Lumbar Intervertebral Disc Degeneration

Vadapalli , Mulukutla , Vadapalli , Vedula RR

STUDY DESIGN: Observational comparative study. PURPOSE: To compare fractional anisotropy (FA) maps with T2 values of the nucleus pulposus (NP) and annulus fibrosus (AF) of intervertebral discs in healthy volunteers and...
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Correlation of Cervical Disc Degeneration with Sagittal Alignments of Cervical Spine

Jeon DG, Park J, Park JH, Yun WH

OBJECTIVE: To determine the relationship between cervical sagittal parameters and the degree of the cervical disc degeneration at each cervical level by using cervical plain radiographs and disc degeneration grading. METHOD:...
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The Concept for A Standalone Lordotic Endoscopic Wedge Lumbar Interbody Fusion: The LEW-LIF

Lewandrowski KU, Ransom NA, Ramírez León JF, Yeung A

OBJECTIVE: To review concepts of a standalone endoscopically assisted lumbar interbody fusion as a simplified method to treat spinal instability. METHODS: MacNab outcomes and complications were analyzed in a series of...
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Dual-Layer Spectral Detector CT Discography of the Lumbar Spine: A Preliminary Study

Chae HD, Hong SH, Choi JY, Yoo HJ, Moon SJ, Chang MY

PURPOSE: To assess the feasibility of spectral detector CT (SDCT) with axial maximum-intensity projection (MIP) reconstruction for the evaluation of lumbar CT discography. MATERIALS AND METHODS: We retrospectively evaluated 44 disc...
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Biomechanical Analysis of Biodegradable Cervical Plates Developed for Anterior Cervical Discectomy and Fusion

Cho PG, Ji GY, Park SH, Shin DA

STUDY DESIGN: In-vitro biomechanical investigation. PURPOSE: To evaluate the biomechanical effects of the degeneration of the biodegradable cervical plates developed for anterior cervical discectomy and fusion (ACDF) on fusion and adjacent...
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Evaluation of the Degenerative Changes of the Distal Intervertebral Discs after Internal Fixation Surgery in Adolescent Idiopathic Scoliosis

Dehnokhalaji M, Golbakhsh , Siavashi B, Talebian P, Javidmehr , Bozorgmanesh M

STUDY DESIGN: Retrospective study. PURPOSE: Lumbar intervertebral disc degeneration is an important cause of low back pain. OVERVIEW OF LITERATURE: Spinal fusion is often reported to have a good course for adolescent...
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Trends and Costs of External Electrical Bone Stimulators and Grafting Materials in Anterior Lumbar Interbody Fusion

D'Oro A, Buser Z, Brodke DS, Park JB, Yoon ST, Youssef JA, Meisel HJ, Radcliff K, Hsieh P, Wang JC

STUDY DESIGN: Retrospective review. PURPOSE: To identify the trends in stimulator use, pair those trends with various grafting materials, and determine the influence of stimulators on the risk of revision surgery. OVERVIEW...
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Lumbar Extensor Muscle Size and Isometric Muscle Strength in Women with Symptomatic Lumbar Degenerative Diseases

Seo YG, Park WH, Lee CS, Kang KC

STUDY DESIGN: A cross-sectional design. PURPOSE: To determine the characteristics of lumbar extensor muscle (LEM) size and isometric muscle strength and examine their correlations in women with lumbar degenerative diseases (LDDs). OVERVIEW...
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In Vitro Biomechanical and Fluoroscopic Study of a Continuously Expandable Interbody Spacer Concerning Its Role in Insertion Force and Segmental Kinematics

Torretti J, Harris JA, Bucklen BS, Moldavsky , Khalil SE

STUDY DESIGN: In vitro cadaveric study. PURPOSE: To compare biomechanical performance, trial and implant insertion, and disc distraction during implant placement, when two interbody devices, an in situ continuously expandable spacer...
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Factors Associated with the Symptoms of Young Adults with L5 Spondylolysis

Kim MW, Lee KY, Lee S

STUDY DESIGN: A retrospective cohort study. PURPOSE: To investigate the factors affecting symptoms in young adults with L5 spondylolysis. OVERVIEW OF LITERATURE: L5 spondylolysis is a common disease. However, not all patients...
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Lumbosacral Transitional Vertebra-Related Low Back Pain: Resolving the Controversy

Gopalan B, Yerramshetty JS

STUDY DESIGN: Case control study. PURPOSE: The association of lumbosacral transitional vertebra (LSTV) with low back pain (LBP) is controversial, as is the role of occupational physical activity and radiological spinal...
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The Effect of Cervical Lordosis on Cervical Disc Degeneration in Patients with a High T1 Slope

Hong SH, Lee SH, Park BM, Song KS, Lim ST

STUDY DESIGN: Retrospective evaluation. OBJECTIVES: To analyze the effect of cervical lordosis on cervical disc degeneration in patients with a high T1 slope. SUMMARY OF LITERATURE REVIEW: The T1 slope is known...
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Relationship between Lumbar Disc Degeneration and Back Muscle Degeneration

Song KS, Lee SH, Park BM, Lee SK, Lee M, Yeom JU, Lee CY, Lee HM

STUDY DESIGN: Retrospective evaluation. OBJECTIVES: To determine the relationship between lumbar disc degeneration and back muscle degeneration. SUMMARY OF LITERATURE REVIEW: In the degenerative cascade of the spine described by Kirkaldy-Willis, degeneration...
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Clinical Relationship of Degenerative Changes between the Cervical and Lumbar Spine

Morishita , Buser Z, D'Oro A, Shiba K, Wang JC

STUDY DESIGN: Retrospective, observational, case series. PURPOSE: To elucidate the prevalence of degenerative changes in the cervical and lumbar spine and estimate the degenerative changes in the cervical spine based on...
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