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Avian Influenza: Should China Be Alarmed?

Su Z, Xu H, Chen J

Avian influenza has emerged as one of the primary public health concern of the 21st century. Influenza strain H5N1 is capable of incidentally infecting humans and other mammals. Since their...
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Control of Avian Influenza: Calls for International Collaboration

Seong BL, Jung EJ

  • KMID: 2303879
  • Korean J Epidemiol.
  • 2006 Jun;28(1):36-40.
The 1918 "Spanish Flu", cause of the largest causality rate ever recorded in human history with 50 million deaths, is genetically related to the current H5N1 virus, suggesting the potential...
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Overview of Pandemic Influenza

Kim WJ

  • KMID: 792365
  • J Prev Med Public Health.
  • 2005 Nov;38(4):373-378.
Influenza virus has a unique characteristics of annual epidemics of acute respiratory disease with attack rate of 10%-30% of the population. It is also the classical emerging infectious disease causing...
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Pandemic Threat Posed by Avian Influenza A Viruses

Lee WK

  • KMID: 1892722
  • Korean J Clin Microbiol.
  • 2004 Sep;7(2):95-104.
Phylogenetic studies of influenza A viruses have revealed species-specific lineages of viral genes, and that aquatic birds are the source of all influenza viruses in other animal species including humans,...
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Experimental infection of chickens, ducks and quails with the highly pathogenic H5N1 avian influenza virus

Jeong OM, Kim MC, Kim MJ, Kang HM, Kim HR, Kim YJ, Joh SJ, Kwon JH, Lee YJ

Highly pathogenic avian influenza viruses (HPAIV) of the H5N1 subtype have spread since 2003 in poultry and wild birds in Asia, Europe and Africa. In Korea, the highly pathogenic H5N1...
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Experimental infection and pathology of clade 2.2 H5N1 virus in gulls

Gulyaeva M, Sharshov K, Zaykovskaia AV, Shestopalova LV, Shestopalov AM

During 2006, H5N1 HPAI caused an epizootic in wild birds, resulting in a die-off of Laridae in the Novosibirsk region at Chany Lake. In the present study, we infected common...
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Reverse genetic platform for inactivated and live-attenuated influenza vaccine

Jung EJ, Lee KH, Seong BL

Influenza vaccine strains have been traditionally developed by annual reassortment between vaccine donor strain and the epidemic virulent strains. The classical method requires screening and genotyping of the vaccine strain...
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The Current Trend of Avian Influenza Viruses in Bioinformatics Research

Ahn I, Son HS

OBJECTIVES: Since the first human infection from avian influenza was reported in Hong Kong in 1997, many Asian countries have confirmed outbreaks of highly pathogenic H5N1 avian influenza viruses....
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Tissue distribution of sialic acid-linked influenza virus receptors in beagle dogs

Ning ZY, Wu XT, Cheng YF, Qi WB, An YF, Wang H, Zhang GH, Li SJ

Reports of influenza A virus infections in dogs has received considerable attention from veterinarians, virologists, and epidemiologists. Interaction between influenza viral hemagglutinin and cell oligosaccharides containing sialic acid residues results...
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Production and immunogenicity of chimeric virus-like particles containing the spike glycoprotein of infectious bronchitis virus

Lv L, Li X, Liu G, Li R, Liu Q, Shen H, Wang W, Xue C, Cao Y

Infectious bronchitis virus (IBV) poses a severe threat to the poultry industry and causes heavy economic losses worldwide. Vaccination is the most effective method of preventing infection and controlling the...
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Optimized clade 2.3.2.1c H5N1 recombinant-vaccine strains against highly pathogenic avian influenza

Jang JW, Lee CY, Kim IH, Choi JG, Lee YJ, Yuk SS, Lee JH, Song CS, Kim JH, Kwon HJ

A/Puerto Rico/8/34 (PR8)-derived recombinant viruses have been used for seasonal flu vaccines; however, they are insufficient for vaccines against some human-fatal H5N1 highly pathogenic avian influenza (HPAI) viruses (HPAIV) due...
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