Yonsei Med J.  2007 Aug;48(4):586-594. 10.3349/ymj.2007.48.4.586.

Avian Influenza: Should China Be Alarmed?

  • 1Department of Microbiology and Immunology, Institute of Clinical Laboratory Medicine, Jiangsu University, Zhenjiang, China. xuhx@ujs.edu.cn, szl30@yeah.net


Avian influenza has emerged as one of the primary public health concern of the 21st century. Influenza strain H5N1 is capable of incidentally infecting humans and other mammals. Since their reemergence in 2003, highly pathogenic avian influenza A (H5N1) viruses have been transmitted from poultry to humans (by direct or indirect contact with infected birds) in several provinces of Mainland China, which has resulted in 22 cases of human infection and has created repercussions for the Chinese economy. People have been concerned whether a new pandemic will occur in the future. The eradication of pathogenic avian influenza viruses appears to be the most effective way to prevent an influenza pandemic. This paper will examine the features of H5N1, including incidence, infection, immunity, clinical management, prevention and control, and therapy in Mainland China.


Avian influenza; H5N1; innate immune; adaptive immune; prevention; control
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