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Potential Role of the Sigma-1 Receptor Chaperone in the Beneficial Effects of Donepezil in Dementia with Lewy Bodies

Hashimoto

  • KMID: 2171197
  • Clin Psychopharmacol Neurosci.
  • 2013 Apr;11(1):43-44.
No abstract available.
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Spinal Subdural Hemorrhage as a Cause of Post-Traumatic Delirium

Se YB, Chun HJ, Yi HJ

A 64-year-old man with TBI was admitted to our institute. In following days, he showed unusual behavior of agitation, restlessness, emotional instability and inattention. Post-traumatic delirium was tentatively diagnosed, and...
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Pharmacological Treatment in Alcohol-induced Cognitive Disorder

Kim DJ, Joe KH

  • KMID: 2340903
  • J Korean Med Assoc.
  • 2008 Jan;51(1):84-89.
Alcohol-induced cognitive disorder is a very severe problem in problem alcohol drinker and alcohol itself seems to be one of the main causalities in the development of senile dementia. However,...
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Why Do We Need Multifunctional Neuroprotective and Neurorestorative Drugs for Parkinson's and Alzheimer's Diseases as Disease Modifying Agents

Youdim MB

Parkinson's disease (PD) and Alzheimer's Disease (AD) are severe neurodegenerative disorders, with no drugs that are currently approved to prevent the neuronal cell loss characteristic in brains of patients suffering...
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Pharmacological Treatment for Delirium in Cancer Patients

Lee PJ, Hahm BJ

  • KMID: 2341610
  • J Korean Neuropsychiatr Assoc.
  • 2010 Jan;49(1):20-25.
OBJECTIVES: Despite the fact that delirium is a frequent neuropsychiatric disorder in cancer patients, there are, in Korea, no guidelines for the pharmacological treatment of such delirium. This systematic review...
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Bilateral Thalamic Ischemic Injury : A case report

Kim SH, Seok H, Lee JB, Suh JW

  • KMID: 2325333
  • J Korean Acad Rehabil Med.
  • 2009 Apr;33(2):242-245.
Thalamic infarction is frequently bilateral due to the nature of the vascular supply to the thalamic region, and is usually caused by cardiogenic embolism or emboli originating from the proximal...
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Nonpharmacological Interventions for Alzheimer's Disease

Lee SB, Kim KW

Although acetylcholinesterase inhibitors (e.g., tacrine, donepezil, rivastigmine, and galantamine) and NMDA receptor antagonists (e.g., memantin) have demonstrated efficacy in the temporal symptomatic control of cognitive decline and daily function in...
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Drug Induced Parkinsonism Caused by the Concurrent Use of Donepezil and Risperidone in a Patient With Traumatic Brain Injuries

Kang SH, Kim DK

A 69-year-old male patient with previous history of traumatic brain injury 5 months ago was admitted to the Department of Neuropsychiatry because of aggressive behavior and delusional features. After starting...
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Whether Alzheimer's Disease is Responsive to a Single Oral Dose of Donepezil and this Response is Predictive Factor in Alzheimer's Disease

Kwak YT, Yang Y, Noh YW

  • KMID: 1502561
  • Korean J Biol Psychiatry.
  • 2011 Feb;18(1):36-45.
OBJECTIVES: Though a proportion of Alzheimer's disease(AD) patients treated with donepezil have shown positive response on cognition, but the responders' characteristics are still uncertain. This study attempts to identify whether...
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MAO-inhibitors in Parkinson's Disease

Riederer P, Laux G

Monoamine oxidase inhibitors (MAO-I) belong to the earliest drugs tried in Parkinson's disease (PD). They have been used with or without levodopa (L-DOPA). Non-selective MAO-I due to their side-effect/adverse reaction...
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Alcohol and Cognitive Disorder

Joe KH, Chun YM, Chai SH, Kim DJ

  • KMID: 2287404
  • Korean J Psychopharmacol.
  • 2009 Jan;20(1):5-14.
Despite epidemiological studies reporting no negative effects of mild to moderate alcohol drinking on cognitive functioning, a recent well-controlled study showed that chronic mild drinking diminished the volume of the...
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Effects of Single Treatment of Anti-Dementia Drugs on Sleep-Wake Patterns in Rats

Jung JY, Roh M, Ko KK, Jang HS, Lee SR, Ha JH, Jang IS, Lee HW, Lee MG

We studied the effects of acetylcholinesterase inhibitors, donepezil and galantamine, and an N-methyl-D-aspartate (NMDA) receptor blocker, memantine, on sleep-wake architecture in rats. Screw electrodes were chronically implanted into the frontal...
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Comparative Assessment of Clinical Efficacy after 12-Month Clinical Trial of Donepezil between the Patients with Pure Alzheimer's Disease and Mixed Dementia

Kang HS, Ahn IS, Yun JH, Moon YJ, Hwang TY, Lee YM, Kim H, Chung JW, Kim DK

  • KMID: 1462769
  • J Korean Geriatr Psychiatry.
  • 2010 Jun;14(1):58-64.
OBJECTIVES: The purpose of this study was to compare the efficacy of donepezil treatment between patients with pure Alzheimer's disease (AD) and Mixed dementia (MD) during a 12-month trial. METHODS: A...
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Effect of Indacaterol on Cough and Phlegm in Chronic Obstructive Pulmonary Disease Patients: A Meta-Analysis of Five Randomized Controlled Trials

Park J, Lee JS, Rhee C, Oh YM

We investigated the effects of indacaterol on cough and phlegm in patients with stable chronic obstructive pulmonary disease (COPD). We performed a meta-analysis with five randomized controlled trials (RCTs) of...
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Multi Target Neuroprotective and Neurorestorative Anti-Parkinson and Anti-Alzheimer Drugs Ladostigil and M30 Derived from Rasagiline

Youdim MB

Present anti-PD and -AD drugs have limited symptomatic activity and devoid of neuroprotective and neurorestorative property that is needed for disease modifying action. The complex pathology of PD and AD...
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