- Potential Roles of Innate Immune Chemokine and Cytokine Network on Lipopolysaccharide-Based Therapeutic Approach in Ovarian Cancer
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Ignacio RM, Lee ES, Son DS
- KMID: 2450207
- Immune Netw.
- 2019 Jun;19(3):e22.
- doi: 10.4110/in.2019.19.e22
Ovarian cancer (OC), the deadliest gynecological cancer, results in poor overall survival, urgently requiring a novel therapeutic approach. As cumulative exposures to endotoxins decreased OC risk epidemiologically, we evaluated if... -
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- Chemokine Network and Overall Survival in TP53 Wild-Type and Mutant Ovarian Cancer
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Ignacio RM, Lee ES, Wilson AJ, Beeghly-Fadiel A, Whalen MM, Son DS
- KMID: 2419774
- Immune Netw.
- 2018 Aug;18(4):e29.
- doi: 10.4110/in.2018.18.e29
Ovarian cancer (OC) has the highest mortality rate among gynecological malignancies. Because chemokine network is involved in OC progression, we evaluated associations between chemokine expression and survival in tumor suppressor... -
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- Differential Chemokine Signature between Human Preadipocytes and Adipocytes
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Ignacio RM, Gibbs CR, Lee ES, Son DS
- KMID: 2299793
- Immune Netw.
- 2016 Jun;16(3):189-194.
- doi: 10.4110/in.2016.16.3.189
Obesity is characterized as an accumulation of adipose tissue mass represented by chronic, low-grade inflammation. Obesity-derived inflammation involves chemokines as important regulators contributing to the pathophysiology of obesity-related diseases such... -
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- Obesity-Induced Peritoneal Dissemination of Ovarian Cancer and Dominant Recruitment of Macrophages in Ascites
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Ignacio RM, Lee ES, Wilson AJ, Beeghly-Fadiel A, Whalen MM, Son DS
- KMID: 2429839
- Immune Netw.
- 2018 Dec;18(6):e47.
- doi: 10.4110/in.2018.18.e47
One-fifth of cancer deaths are associated with obesity. Because the molecular mechanisms by which obesity affects the progression of ovarian cancer (OC) are poorly understood, we investigated if obesity could... -
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- Augmented Serum Amyloid A1/2 Mediated by TNF-induced NF-κB in Human Serous Ovarian Epithelial Tumors
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Choi H, Ignacio RM, Lee ES, Wilson AJ, Khabele D, Son DS
- KMID: 2376870
- Immune Netw.
- 2017 Apr;17(2):121-127.
- doi: 10.4110/in.2017.17.2.121
Tumor necrosis factor-α (TNF) is well known to be involved in the immune system and ovarian inflammation. Ovarian cancer is an inflammation-related malignancy that lacks early screening strategies, resulting in... -
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- Localization of Serum Amyloid A3 in the Mouse Ovary
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Choi H, Ignacio RM, Lee ES, Roby KF, Terranova , Son DS
- KMID: 2388080
- Immune Netw.
- 2017 Aug;17(4):261-268.
- doi: 10.4110/in.2017.17.4.261
Tumor necrosis factor-α (TNF-α) induces serum amyloid A (SAA) 3 among acute-phase proteins in mouse granulosa cells by activating NF-κB signaling via p55 TNF-α receptor type 1. However, the localization... -
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