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Diagnosis and treatment of interstitial lung disease: focusing on idiopathic pulmonary fibrosis

Kang HR, Choi SM

Interstitial lung disease (ILD) is a rare condition characterized by extensive inflammation and fibrosis mainly involving the pulmonary interstitium or alveoli. Usually, patients with ILD clinically present with chronic cough...
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Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases: Part 5. Connective Tissue Disease Associated Interstitial Lung Disease

Koo SM, Kim SY, Choi SM, Lee HK, on behalf of Korean Interstitial Lung Diseases Study Group

Connective tissue disease (CTD) is a collection of disorders characterized by various signs and symptoms such as circulation of autoantibodies in the entire system causing damage to internal organs. Interstitial...
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Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases: Part 3. Idiopathic Nonspecific Interstitial Pneumonia

Lee J, Kim YH, Kang JY, Jegal Y, Park SY, on behalf of Korean Interstitial Lung Diseases Study Group

Idiopathic nonspecific interstitial pneumonia (NSIP) is one of the varieties of idiopathic interstitial pneumonias. Diagnosis of idiopathic NSIP can be done via multidisciplinary approach in which the clinical, radiologic, and...
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Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases: Part 1. Introduction

Park SW, Baek AR, Lee HL, Jeong SW, Yang SH, Kim YH, Chung MP, on behalf of the Korean Interstitial Lung Diseases Study Group

Idiopathic interstitial pneumonia (IIP) is a histologically identifiable pulmonary disease without a known cause that usually infiltrates the lung interstitium. IIP is largely classified into idiopathic pulmonary fibrosis, idiopathic non-specific...
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Clinical Outcomes of Lung Transplantation: Experience at Asan Medical Center

Jeong YH, Choi S, Park SI, Kim DK, Asan Medical Center Lung Transplantation Team

BACKGROUND: Lung transplantation is a life-saving procedure in patients with end-stage lung disease, and is increasingly performed in Korea. METHODS: We retrospectively evaluated the outcomes of patients who received a lung...
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A Case of Desquamative Interstitial Pneumonia with an Increased Number of Eosinophils in Bronchoalveolar Lavage Fluid

Choi Y, Kim TH, Kang LH, Kim HJ, Jang JH, Shin DH, Jeon D

Here, we present a case of desquamative interstitial pneumonia (DIP) that was initially misdiagnosed as chronic eosinophilic pneumonia due to an increased number of eosinophils in the bronchoalveolar lavage fluid...
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Different Responses to Clarithromycin in Patients with Cryptogenic Organizing Pneumonia

Oh JH, Oh DJ, Koo SM, Kim YK, Kim KU, Kim HJ, Kim DW, Uh ST

Cryptogenic organizing pneumonia (COP) is an idiopathic interstitial pneumonia characterized by a subacute course and favorable prognosis with corticosteroids. However, some patients show resistance to steroids. Macrolides have been used...
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Interstitial Lung Disease in Connective Tissue Disease

Song JW

Interstitial lung disease (ILD) is one of the most serious pulmonary complications of connective tissue diseases (CTDs), resulting in significant morbidity and mortality. ILD is frequently seen in CTDs, particularly...
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Idiopathic Pleuroparenchymal Fibroelastosis Presenting in Recurrent Pneumothorax: A Case Report

Noh HJ, Seo Y, Huo SM, Kim TJ, Kim HL, Song JS

Idiopathic pleuroparenchymal fibroelastosis (PPFE) is a rare, recently classified entity that consists of pleural and subjacent parenchymal fibrosis predominantly in the upper lungs. In an official American Thoracic Society/European Respiratory...
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Clinical Significance of Serum Autoantibodies in Idiopathic Interstitial Pneumonia

Kang BH, Park JK, Roh JH, Song JW, Lee CK, Kim M, Jang SJ, Colby TV, Kim DS

Although autoantibodies are routinely screened in patients with idiopathic interstitial pneumonia, there are no reliable data on their clinical usefulness. The aim of this study was to investigate the prognostic...
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Radiologic Approach to the Idiopathic Interstitial Pneumonias

Oh YW

  • KMID: 2082452
  • Korean J Med.
  • 2013 Apr;84(4):489-497.
Idiopathic interstitial pneumonias (IIP), a heterogeneous group of diffuse parenchymal lung diseases, include seven clinicopathologic entities: idiopathic pulmonary fibrosis (IPF), nonspecific interstitial pneumonia (NSIP), cryptogenic organizing pneumonia (COP), acute interstitial...
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A Case of Bronchiolitis Interstitial Pneumonitis

Kim MJ, Kim YS, Kim DH, Jun TY, Lee SJ, Kim YJ

  • KMID: 2267916
  • Korean J Med.
  • 2013 Jan;84(1):105-110.
Interstitial lung diseases are diagnosed based on clinical, radiological, and histopathological findings. There are various kinds of interstitial lung diseases involving both the interstitium and bronchioles. Bronchiolitis interstitial pneumonitis (BIP)...
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Intralobar Pulmonary Sequestration Showing Increased Serum CA19-9

Ahn YH, Song MJ, Park SH

  • KMID: 2319852
  • Tuberc Respir Dis.
  • 2012 Jun;72(6):507-510.
Carbohydrate antigen 19-9 (CA19-9) is a specific tumor marker of the biliary, pancreatic and gastrointestinal tracts. CA19-9 is occasionally elevated in serum in patiens with benign pulmonary diseases such as...
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Treatment Response and Long Term Follow-up Results of Nonspecific Interstitial Pneumonia

Lee JY, Jin SM, Lee BJ, Chung DH, Jang BG, Park HS, Lee SM, Yim JJ, Yang SC, Yoo CG, Han SK, Shim YS, Kim YW

The purpose of this study was to investigate the long-term clinical course of non-specific interstitial pneumonia (NSIP) and to determine which factors are associated with a response to steroid therapy...
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A Case of Asymptomatic, Localized, and Idiopathic Diffuse Alveolar Damage

Jeon YD, Hong HC, Joh JS, Jung JY, Min JW, Park SY, Lee GR

  • KMID: 2319812
  • Tuberc Respir Dis.
  • 2012 Apr;72(4):386-389.
Diffuse alveolar damage (DAD) is a histological change in lung tissue, and is generally caused by an acute lung injury, which is characterized by bilateral and widespread damages. Localized DAD...
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Impact of Rheumatologic Consultations on Detecting Interstitial Lung Disease Associated with Connective Tissue Disease

Song ME, Lee J, Roh SH

OBJECTIVE: In patients with interstitial lung disease (ILD) associated with connective tissue disease (CTD), chronic ILD related symptoms may often dominate the clinical picture or precede systemic findings and thus...
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Interleukin-13 and Its Receptors in Idiopathic Interstitial Pneumonia: Clinical Implications for Lung Function

Park SW, Ahn MH, Jang HK, Jang AS, Kim DJ, Koh ES, Park JS, Uh ST, Kim YH, Park JS, Paik SH, Shin HK, Youm W, Park CS

Idiopathic interstitial pneumonia (IIP) is characterized by varying degrees of interstitial fibrosis. IL-13 and IL-4 are strong inducers of tissue fibrosis, whereas IFN-gamma has antifibrotic potential. However, the roles of...
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A Case Report of Usual Interstitial Pneumonia after Treatment of Bronchopneumonia

Lee JU, Shin SR, Kim HJ, Park JH

Usual interstitial pneumonia (UIP) is one type of idiopathic interstitial pneumonia, characterized by its poor prognosis and gradual deterioration of clinical course. So it is important to distinguish UIP from...
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A Case of Idiopathic Bronchiolocentric Interstitial Pneumonia

Kang JY, Jung JI, Lee KY, Kim TJ, Lee JW, Lee WH, Chung HS, Yoon HK, Song JS

Idiopathic bronchiolocentric interstitial pneumonia is one of idiopathic interstitial pneumonia, which has a relatively aggressive course and poor prognosis. It is characterized by diffuse centrilobular nodules radiologically with mainly bronchiolocentric...
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2008 National Survey of Idiopathic Interstitial Pneumonia in Korea

Scientific Committee of the Korean Academy of Tuberculosis and Respiratory Diseases

  • KMID: 2319162
  • Tuberc Respir Dis.
  • 2009 Feb;66(2):141-151.
BACKGROUND: There is limited data on the epidemiology and relative frequency of idiopathic interstitial pneumonia (IIP) worldwide. This survey was performed to assess the epidemiology and relative frequency of IIP...
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