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Therapeutic Hypothermia for Hypoxic-Ischemic Encephalopathy in Newborn Infants

Sung IK

Neonatal hypoxic-ischemic encephalopathy (HIE) is an ongoing process, which may persist for weeks to years after an acute asphyxial insult, causing delayed programmed cell death. The typical clinical signs and...
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Myoclonic status epilepticus in hypoxic ischemic encephalopathy which recurred after somatosensory evoked potential testing

Kim S, Kim Y, Kim S, Lee SY

A 77-year-old male with amyotrophic lateral sclerosis had a hypoxic event. After resuscitation, generalized myoclonus appeared and resolved after two days. Five days after the hypoxic event, myoclonic seizures re-emerged...
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Neurodevelopmental Outcomes According to Brain Injury Patterns in Neonates with Postasphyxial Hypoxic Ischemic Encephalopathy

Jeong SY, Choi SY, Chang YP, Lee YS

PURPOSE: To investigate the relationship between brain injury patterns on magnetic resonance imaging (MRI) and neurodevelopmental outcomes in neonates with postasphyxial hypoxic ischemic encephalopathy (HIE). METHODS: Clinical characteristics and brain MRI...
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Human Umbilical Cord Blood CD34-Positive Cells as Predictors of the Incidence and Short-Term Outcome of Neonatal Hypoxic-Ischemic Encephalopathy: A Pilot Study

Hassanein , Nasr Eldin MH, Amer HA, Abdelhamid AE, El Houssinie M, Ibrahim A

BACKGROUND AND PURPOSE: Neonatal hypoxic-ischemic encephalopathy (HIE) is one of the leading causes of neurological handicap in developing countries. Human umbilical cord blood (hUCB) CD34-positive (CD34⁺) stem cells exhibit the...
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Prediction of Neurodevelopmental Outcome in Hypoxic Ischemic Encephalopathy at 12 Months: Correlation of Brain MRI and EEG

Jo HC, Kim EJ, Lee JH, Jung DE, Park MS, Kim SH

PURPOSE: The aims of this study were to estimate the neurodevelopmental outcome of hypoxic-ischemic encephalopathy (HIE) at 12 months, and determine the usefulness of brain magnetic resonance imaging (MRI) and...
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NeuroRehabilitation after Hypoxic-ischemic Encephalopathy

Leigh JH, Oh BM

The number of survivors after hypoxic-ischemic encephalopathy has been increasing due to recent progress in medical system and care. Impairment after injury ranges from mild memory deficit to vegetative state...
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Common Complications after Hypoxic-ischemic Encephalopathy

Lim SH

Hypoxic-ischemic encephalopathy (HIE) is one of the major disease for neuro-rehabilitation, as well as one of the important impairment. HIE typically shows global deterioration of brain function with relative preservation...
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Prediction of Neurological Recovery in Patients with Hypoxic-ischemic Encephalopathy

Yoon SY, Kim JK, Kim YW

The incidence of hypoxic-ischemic encephalopathy (HIE) is not well known, however, the common causes of hypoxic-ischemic encephalopathy are sudden cardiac arrest, acute respiratory failure and carbon monoxide poisoning. Due to...
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The Chracteristics of Hypoxic Ischemic Encephalopathy with Seizures in Children

Jung SY, Hwang SH, Kim DH, Jun YH, Son BK, Kwon YS

  • KMID: 1961823
  • J Korean Child Neurol Soc.
  • 2013 Sep;21(3):92-99.
PURPOSE: This study was aimed to evaluate the clinical features of hypoxic ischemic encephalopathy(HIE) in children with and without seizures. METHODS: Fifty five children who had been diagnosed as HIE at...
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eNOS Gene Polymorphisms in Perinatal Hypoxic-Ischemic Encephalopathy

Cho M, Hyun KS, Chung DC, Choi IY, Kim MJ, Chang YP

  • KMID: 2459588
  • Korean J Pathol.
  • 2009 Aug;43(4):306-311.
BACKGROUND: In perinatal hypoxic-ischemic encephalopathy (HIE), cerebral blood flow is impaired and the activity of nitric oxide systhase (NOS) is markedly increased. For the association with the development of a...
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The Correlation between the Severity of Hypoxic Ischemic Encephalopathy and the Development of Acute Renal Failure in Asphyxiated Neonates

Park SS, Chung SH, Song JH, Kim SK, Kim SD, Cho BS

  • KMID: 1898234
  • J Korean Soc Pediatr Nephrol.
  • 2007 Apr;11(1):32-40.
PURPOSE: We performed this study to determine the incidence of acute renal failure(ARF) in birth asphyxia and to correlate the severity of asphyxia and hypoxic-ischemic encephalopathy (HIE) and ARF in...
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Predicting Factors for Neurologic Outcome in Full-term Neonates with Hypoxic-Ischemic Encephalopathy

Yeo CY, Kim DK, Kim SH, Song ES, Woo YJ, Choi YY

  • KMID: 2099108
  • J Korean Soc Neonatol.
  • 2006 Nov;13(2):226-232.
PURPOSE:Hypoxic injury during delivery and subsequent ischemic encephalopathy is still remained as one of the important cause of neonatal death and associated with neurologic complication. We investigated the predicting factors...
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Effects of NG-monomethyl-L-arginine and L-arginine on cerebral hemodynamics and energy metabolism during reoxygenation-reperfusion after cerebral hypoxia-ischemia in newborn piglets

Ko SY, Kang S, Chang YS, Park EA, Park WS

PURPOSE: This study was carried out to elucidate the effects of nitric oxide synthase(NOS) inhibitor, NG-monomethyl-L-arginine(L-NMMA) and nitric oxide precursor, L-arginine(L-Arg) on cerebral hemodynamics and energy metabolism during reoxygenation-reperfusion(RR) after...
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Effects of 7-Nitroindazole on Brain Cell Membrane Function and Energy Metabolism during Transient Global Cerebral Hypoxia-Ischemia and Reoxygenation-Reperfusion in Newborn Piglets

Choi CW, Hwang JH, Chang YS, Park WS

  • KMID: 2278889
  • Korean J Pediatr.
  • 2004 Feb;47(2):204-209.
PURPOSE: Our study was undertaken to discover whether a selective neuronal nitric oxide synthase inhibitor, 7-nitroindazole, influences brain cell membrane function and energy metabolism during and after transient global hypoxia-ischemia(HI)...
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Change in the Intrathecal Cytokine level in Hypoxic-ischemic Encephalopathy after Cardiac Arrest

Lee WJ, Park KN, Jeong SK, Youn CS, Kim SK

  • KMID: 1998720
  • J Korean Soc Emerg Med.
  • 2003 Dec;14(5):494-499.
PURPOSE: This study was performed to evaluate the changes in the IL-1beta and the IL-6 concentrations in cerebrospinal fluid (CSF) after initial successful cardiopulmonary resuscitation (CPR), to examine the difference...
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Management of Hypoxic-Ischemic Encephalopathy: Present and Future

Kim WT

  • KMID: 1838158
  • Korean J Perinatol.
  • 2003 Dec;14(4):393-399.
No abstract available.
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A Case of Neonatal Hypoxic Ischemic Encephalopathy caused by Amniotic Fluid Embolism

Yoon HK, Kim SH, Kook JH, Choi YY, Oh HS, Nam JH

  • KMID: 2280534
  • Korean J Perinatol.
  • 2003 Jun;14(2):190-195.
Amniotic fluid embolism, one of the leading causes of maternal death, is a rare event, however, it can cause maternal death and neonatal morbidity when it unrecognized and untreated effectively....
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The Incidence of Feeding Intolerance in the Full Term Neonates with Hypoxic-Ischemic Encephalopathy

Song YG, Choi SD, Hur JK, Oh CK, Chun CS

  • KMID: 2099041
  • J Korean Soc Neonatol.
  • 2002 Nov;9(2):192-197.
PURPOSE: We investigated incidence of feeding intolerance and time when normal enteral feeding can be established in full term neonates with hypoxic-ischemic encephalopathy (HIE). METHODS: We reviewed medical records of 61...
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Effect of Xanthine Oxidase Inhibitor on Cerebral Hypoxia-Ischemia in Neonatal Rats

Choi DH, Oh YK, Park ST

  • KMID: 1946172
  • J Korean Pediatr Soc.
  • 2002 Jun;45(6):732-742.
PURPOSE: In order to evaluate the hypoxia-ischemia(H-I) induced neurotoxicity and the protective effect of xanthine oxidase(XO) inhibitor(allopurinol), cell number, cell viability, lactate dehydrogenase(LDH), protein synthesis(PS) and protein kinase C(PKC) activity...
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Effect of Vitamin E on Cerebral Hypoxia-Ischemia in Neonatal Rats

Seok JE, Oh YK, Park ST

  • KMID: 1946204
  • J Korean Pediatr Soc.
  • 2001 Jul;44(7):764-772.
PURPOSE: In order to evaluate the hypoxia-ischemia induced neurotoxic effect and the protective effect of vitamin E as an antioxidant, cell number and cell viability were measured in cerebral neurons...
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